First look: Notre Dame at Virginia Tech odds and lines

Previewing the Notre Dame Fighting Irish at Virginia Tech Hokies Week 6 matchup, with college football odds, trends and head-to-head records.

The No. 13 Notre Dame Fighting Irish (4-1) meet the Virginia Tech Hokies (3-1) Saturday at Lane Stadium in Blacksburg, Va. Kickoff is scheduled for 7:30 p.m. ET. Below, we look at the Notre Dame vs. Virginia Tech odds and lines; check back for our college football picks and predictions.

The Irish are coming off their first loss of the season, a 24-13 setback at home against sixth-ranked Cincinnati. They failed to cover their only true road game at Florida State Sept. 5 while the Over cashed in that outing.

The Hokies had the week off after dispatching FCS Richmond 21-10 Sept. 25 when they didn’t come close to covering a 29-point number. They’re 1-1 SU/0-2 ATS across the past two, while the Under is 4-0 in all four of their outings.

Rankings according to the AFCA Coaches Poll powered by USA TODAY Sports.

Notre Dame at Virginia Tech odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 8:07 p.m. ET.

  • Money line: Notre Dame -110 (bet $110 to win $100) | Virginia Tech -110 (bet $110 to win $100)
  • Against the spread (ATS): Notre Dame +0.5 (-110) | Virginia Tech -0.5 (-110)
  • Over/Under (O/U): 47.5 (O: -103 | U: -117)

Also see: Betting 101

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2021 betting stats:

  • ML: Notre Dame 4-1 | Virginia Tech 3-1
  • ATS: Notre Dame 2-3 | Virginia Tech 2-2
  • O/U: Notre Dame 3-2 | Virginia Tech 0-4

Notre Dame at Virginia Tech head-to-head

Notre Dame has a 2-1 edge in this all-time series, which only dates back to 2016. The Irish edged the Hokies 21-20 in the most recent meeting Nov. 2, 2019. In the only previous meeting in Blacksburg, Notre Dame came away with a decisive 45-23 victory Oct. 6, 2018.

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