Updated Tennessee Titans at Denver Broncos odds, line, spread, picks and best bets

Previewing the Tennessee Titans at Denver Broncos Week 1 matchup, with updated betting odds and lines, with NFL betting picks, tips and best bets.

The Tennessee Titans and Denver Broncos begin their 2020 regular seasons at Empower Field at Mile High in Denver on Monday at 10:10 p.m. ET (on ESPN). Below, we preview the Titans-Broncos betting odds and lines and make our NFL picks and best bets.

Titans at Broncos betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 1 p.m.

  • Moneyline: Titans -176 (bet $176, win $100) | Broncos +150 (Bet $100, win $150)
  • Against the Spread/ATS: Titans -3.5 (-110) | Broncos +3.5 (-110)
  • Over/Under: 41.5 (O: -110, U: -110)

Special Colorado Week 1 Promotion: Place any $1 bet on the Denver Broncos, receive $100 credit for free bets into your account! Regardless of your bet outcome, you win! Place your legal, online wagers in Colorado at BetMGM. Terms and conditions apply. Bet now!

Titans at Broncos game notes

  • The Titans qualified for the playoffs in 2019, going 9-7 with a 7-5 record against AFC teams. They were 8-7-1 against the spread with 10 over results in 16 regular-season games.
  • The Broncos managed a 7-9 record with a 5-3 mark at home in 2019, while going 9-7 ATS with seven over results in their 16 regular-season battles.
  • The Titans turned the keys over to QB Ryan Tannehill after the first month of the 2019 season, and he threw for 2,742 yards, 22 touchdowns and just six interceptions in his 12 games (10 starts). He also rushed for 185 yards and four scores.
  • The Broncos have a new workhorse in the backfield, as RB Melvin Gordon comes over from the division-rival Chargers. He faced the Titans last season as a member of the Bolts, rushing for just 32 yards on 16 carries.
  • The Titans lost 16-0 to the Broncos on the road last season in Week 6. Tannehill took over for Marcus Mariota with 4:56 left in the third quarter and he never looked back.

Titans at Broncos key injuries

Titans

  • CB Adoree’ Jackson (knee) out
  • G Jamil Douglas (hand) out
  • WR Corey Davis (hamstring) questionable
  • LB Vic Beasley (knee) out
  • LB Derick Roberson (knee) out

Broncos

  • LB Mark Barron (hamstring) out
  • WR Courtland Sutton (shoulder) questionable
  • LB Von Miller (ankle) out

Titans at Broncos: Odds, betting lines, picks and prediction

Prediction

Titans 24, Broncos 16

Moneyline (?)

The TITANS (-176) aren’t a bad play on the moneyline if you don’t want to risk laying the points on the road. My personal rule of thumb is betting moneylines -180 or lower. Anything higher than that is just too much risk.

Against the Spread (?)

The TITANS (-3.5, -110) are favored by a field goal and a half on the road, as they look for revenge after last season’s embarrassing shutout loss in the Mile High City last season. That game changed the course of the season for the Titans, as head coach Mike Vrabel changed his signal caller and it proved to be the move of the season. The Titans are just healthier than the Broncos in this one. Not having Miller is bad news for the Broncos, as they try to corral RB Derrick Henry. With Hamler and Sutton also nursing hamstring injuries, QB Drew Lock might have fewer speedy targets to choose from.

Over/Under (?)

O/U (41.5) is the total, and it’s too close for comfort. I expect a total of 40 points in this one. The over has cashed in four straight Monday appearances for the Titans, and the over is 6-1 in their past seven as a favorite. The over is 8-2 in Denver’s past 10 season openers, but the under is 5-2 in their past seven appearances on Monday, and 15-6-1 in the past 22 as an underdog. AVOID.

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NFL Week 1 Betting Guide: Betting promotions, latest odds, lines, picks and best bets

Breaking down the NFL Week 1 betting slate, with odds, lines, spreads and betting promotions

The 2020 NFL Season is in full-swing today, with a full slate of exciting Week 1 matchups.

And with a full slate, we have a ton of NFL betting opportunities at our disposal today. Moneylines, spreads, over/unders, prop bets and more! With legal, online sports betting activating around the country, it has never been easier.

If you are in Colorado, Indiana, New Jersey or West Virginia, place your online, legal sports wagers at BetMGM Sportsbook. They have a number of special promotions across today’s games, too.

Week 1 NFL Betting Odds, Lines, Spreads, Picks

New York Jets (+255) @ Buffalo Bills (-278)

  • The Bills are 6.5-point favorites over the Jets.
  • Over/Under: 39.5 points
  • BetMGM Promotion: Special New Jersey Week 1 Promotion! Place any $1 bet on the New York Jets, receive $100 in free bets! Regardless of your bet outcome, you win! Place your legal, online wagers in New Jersey at BetMGM. Terms and conditions apply. Bet now!
  • Betting preview: New York Jets at Buffalo Bills odds, picks and best bets

Philadelphia Eagles (-239) @ Washington Football Team (+195)

Seattle Seahawks (-118) @ Atlanta Falcons (100)

Miami Dolphins (+275) @ New England Patriots (-345)

Week 1 Special Promotion! Bet $1 on any Week 1 moneyline, WIN $100 (in free bets) if ANY team scores a touchdown. Easy win. Place your legal, online bets in CO, IN, NJ and WV at BetMGM. Terms and conditions apply. Bet now!

Green Bay Packers (+120) @ Minnesota Vikings (-139)

Indianapolis Colts (-385) at Jacksonville Jaguars (+310)

Chicago Bears (+115) @ Detroit Lions (-139)

Cleveland Browns (+270) @ Baltimore Ravens (-345)

Las Vegas Raiders (-154) @ Carolina Panthers (+130)

Los Angeles Chargers (-150) @ Cincinnati Bengals (+125)

Tampa Bay Buccaneers (+155) @ New Orleans Saints (-182)

Arizona Cardinals (+250) @ San Francisco 49ers (-313)

Dallas Cowboys (-139) @ Los Angeles Rams (+155)

Pittsburgh Steelers (-250) @ New York Giants (+210)

  • The Steelers are 6-point favorites over the Giants.
  • Over/Under: 45.5 points
  • Special Indiana, New Jersey and West Virginia Week 1 Promotion! Bet $1, WIN $100 (in free bets) if either the New York Giants or Pittsburgh Steelers score a touchdown in their Week 1 game. Place your legal, online sports bets in IN, NJ and WV at BetMGM. Terms and conditions apply. Bet now!
  • Betting preview: Pittsburgh Steelers at New York Giants odds, picks and best bets

Tennessee Titans (-162) @ Denver Broncos (+135)

  • The Titans are 3-point favorites over the Broncos.
  • Over/Under: 41.5 points
  • Special Colorado Week 1 Promotion! Place any $1 bet on the Denver Broncos, receive $100 in free bets! Regardless of your bet outcome, you win! Place your legal, online wagers in Colorado at BetMGM. Terms and conditions apply. Bet now!
  • Betting preview: Tennessee Titans at Denver Broncos odds, picks and best bets

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New York Jets at Buffalo Bills odds, picks and best bets

Previewing the Week 1 matchup between the New York Jets at Buffalo Bills betting odds and lines, with NFL betting picks, tips and best bets.

The New York Jets and Buffalo Bills open their 2020 regular seasons at New Era Field on Sunday at 1:00 p.m. ET (on CBS).

Here we analyze the Week 1 matchup, including the Jets-Bills odds, spread and betting lines and look at the best betting options.

New York Jets at Buffalo Bills betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:30 p.m. ET

  • Moneyline: Bills -278 (bet $278, win $100) | Jets +225 (Bet $100, win $225)
  • Against the Spread/ATS: Bills -6.5 (-112) | Jets +6.5 (-106)
  • Over/Under: 39.5 (O: -110, U: -110)

Special New Jersey Week 1 Promotion! Place any $1 bet on the New York Jets, receive $100 in free bets! Regardless of your bet outcome, you win! Place your legal, online wagers in New Jersey at BetMGM. Terms and conditions apply. Bet now!

New York Jets at Buffalo Bills game notes

  • The Jets made some nice improvements along their offensive line, including spending their first-round pick on OT Mekhi Becton out of Louisville. But they traded S Jamal Adams to Seattle, and LB C.J. Mosley opted out due to COVID-19, so the defense is going to struggle.
  • The Bills haven’t won the AFC East division title since 1995, but many talking heads like what they see. A lot of excitement was generated by adding WR Stefon Diggs on offense, as well as DE Mario Addison to strengthen an already impressive defensive unit.
  • The Jets were 7-9 with a 2-4 record inside the AFC East in 2019, including a split with the Bills. Their 13-6 win in Week 7 came in Buffalo, with the home side resting key players with their playoff seeding already locked in.
  • New York also finished 7-9 ATS and hit the over seven times with nine under results.
  • The Bills went 10-6, but were just 4-4 at home and 3-3 inside the division. They ended up 9-5-2 ATS, and they tied with the Pittsburgh Steelers to have the most under results (12).

New York Jets at Buffalo Bills key injuries

Jets

  • S Marcus Maye (calf, ankle) questionable
  • G Alex Lewis (shoulder) questionable
  • LB Avery Williamson (hamstring) Out
  • QB Joe Flacco (neck) Out

Bills

  • DT Vernon Butler (hamstring) questionable
  • CB Josh Norman (hamstring) Out

New York Jets at Buffalo Bills: Odds, betting lines, picks and prediction

Prediction

Bills 24, Jets 13

Moneyline (?)

Bills (-278) are the play in the regular season opener, but you cannot risk nearly three times your potential return. The Jets (+225), however, will have plenty of problems defensively, and you cannot trust them, either. AVOID.

Against the Spread (?)

The new-look BILLS (-6.5, -112) will get off to a good start, and get in on this before it goes up to a flat seven, or worse, seven and a hook. If Johnny Public jumps in on this and drives this line up, it makes it a bit more perilous. Get on the right side, although I still think Buffalo comes through by double digits.

Over/Under (?)

UNDER 39.5 (-110) is a risky play in this one, as this is the lowest total on the board. But Buffalo’s defense is sick, and they’ll allow very little in the way of points to Gang Green. The Bills are still gelling on offense, and eventually this could be quite the well-oiled machine. But they’re still a work in progress.

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Bills Wire: Josh Allen, Stefon Diggs temper expectations ahead of Week 1

Jets Wire: Tight end group headlines 4 of Jets’ biggest strengths entering 2020

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Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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Dallas Cowboys at Los Angeles Rams odds, picks and best bets

Previewing the Dallas Cowboys at Los Angeles Rams Week 1 betting odds and lines, with NFL betting picks, tips and best bets.

The Dallas Cowboys will not only open the 2020 NFL season against the Los Angeles Rams Sunday night, but they’ll be the first road team to take the field at SoFi Stadium in Inglewood, Calif. Kickoff between these two Super Bowl hopefuls in the NFC is at 8:20 p.m. ET.

Cowboys at Rams betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 3:45 p.m. ET.

  • Moneyline: Cowboys -150 (bet $150, win $100) | Rams +125 (bet $100, win $125)
  • Against the Spread/ATS: Cowboys -2.5 (-110) | Rams +2.5 (-110)
  • Over/Under: 51.5 (O: -110, U: -110)

Get some action on this NFL game or others by placing a legal sports bet in CO, IN, NJ and WV at BetMGM. Bet now!

Cowboys at Rams game notes

  • The last time these teams met, the Cowboys blew out the Rams 44-21 at home. The Rams won the previous two meetings, including a 30-22 victory in the playoffs two seasons ago.
  • The Rams are undefeated in Week 1 under head coach Sean McVay the last three seasons.
  • Dallas has an entirely new coaching staff on its sideline, led by head coach Mike McCarthy and defensive coordinator Mike Nolan.
  • The total has gone Over the projected number in six of the Cowboys’ last seven games against NFC opponents.
  • In their last 16 games against the NFC, the Rams are 12-3-1 against the spread.

Cowboys at Rams key injuries

Cowboys

  • CB Jourdan Lewis (ankle) out

Cowboys at Rams: Odds, betting lines, picks and prediction

Prediction

Cowboys 30, Rams 27

Moneyline (?)

The Rams won’t have home-field advantage this weekend with no fans allowed in SoFi Stadium, making it easier to see why Dallas is favored in this game. On paper, the Cowboys look like the better team, especially after a great offseason.

The Rams lost a ton of talent this spring and have a first-year coordinator leading the defense, which could spell trouble. Take the COWBOYS (-150) to win outright.

Against the Spread (?)

The Cowboys come in as 2.5-point favorites, which is where the line has remained for weeks. Dallas blew out the Rams at home last season behind a dominant offensive showing, and while the score isn’t likely to be as lopsided again, I do like the Cowboys in this one.

Take the COWBOYS -2.5 (-110) to win by a field goal and cover the spread Sunday night in what will be a back-and-forth contest.

Over/Under (?)

The Over/Under of 51.5 is the highest of any game left this week, and by a comfortable margin. Each team boasts stars on both sides of the ball, but there could be some coverage mix-ups and missed tackles on defense after the cancelation of the preseason.

I’m inclined to take the OVER 51.5 (-110) in this game, which could turn into a shootout between QBs Jared Goff and Dak Prescott.

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Pittsburgh Steelers at New York Giants odds, picks and best bets

Previewing Monday’s Pittsburgh Steelers at New York Giants NFL matchup, with NFL betting odds, picks and best bets

The Pittsburgh Steelers and New York Giants begin their 2020 regular seasons at MetLife Stadium in East Rutherford, N.J., Monday at 7:15 p.m. ET (on ESPN). Below, we preview the Steelers-Giants betting odds and lines and make our NFL picks and best bets.

Steelers at Giants betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 3 p.m.

  • Moneyline: Steelers -250 (bet $250, win $100) | Giants +210 (Bet $100, win $210)
  • Against the Spread/ATS: Steelers -6 (-110) | Giants +6 (-110)
  • Over/Under: 45.5 (O: -110, U: -110)

Special Week 1 Promotion! Bet $1, WIN $100 (in free bets) if either the New York Giants or Pittsburgh Steelers score a touchdown in their Week 1 game. Place your legal, online sports bets in IN, NJ and WV at BetMGM. Terms and conditions apply. Bet now!

Steelers at Giants game notes

  • The Steelers had an injury-marred 2019, ending up 8-8 while going 3-5 on the road. They were also 9-7 ATS, while tying for the league lead with 12 under results in their 16 regular-season games.
  • The Giants struggled with a 4-12 record, going 2-6 at home and 1-3 vs. AFC teams last season. They were 7-9 ATS, with 10 over results in their 16 regular-season contests.
  • Giants QB Daniel Jones begins his first full season as the starter, taking over for the retired QB Eli Manning. Jones completed 61.9 percent of his passes for 3,027 yards, 24 touchdowns and 12 interceptions while running for 279 yards and two scores.
  • Giants RB Saquon Barkley rushed for 1,003 yards with six touchdowns and added 52 receptions for 438 yards and two scores. He’ll have a tough time against a Steelers defense which ranked fifth in total yards allowed (304.1) and points allowed (18.9) per game in 2019.
  • Steelers QB Ben Roethlisberger appeared in just one full game and part of another, suffering a season-ending elbow injury in Week 2. With no preseason, this will be his first game action in nearly a full calendar year.

Steelers at Giants key injuries

Steelers

  • G David DeCastro (knee) questionable
  • WR Diontae Johnson (foot) questionable

Giants

  • WR Golden Tate (hamstring) questionable
  • TE Levine Toilolo (hamstring) questionable

Steelers at Giants: Odds, betting lines, picks and prediction

Prediction

Steelers 27, Giants 20

Moneyline (?)

The Steelers (-250) will cost you two and a half times your potential return. In a home game I wouldn’t recommend this play, but especially on the road. AVOID.

New to sports betting? You will need to wager $25 to win $10 if you bet the Steelers to win straight up. If you wager $10 on Pittsburgh, a Steelers win would return $4.

Against the Spread (?)

The STEELERS (-6, -110) have their field general back, as Big Ben returns behind center for the first time since Week 2 of the 2019 season. However, it’s fair to expect some rust, especially with COVID-19 limiting the offseason program and eliminating preseason games. Still, Pittsburgh has a solid running attack to ease him back into the fold, and the Steelers should be able to sneak by with a road cover.

Over/Under (?)

OVER 45.5 (-110) is worth a small-unit play, as I think the over will only clear by a couple of points. The over was just 17-31-1 in primetime games in the 2019 season, or 35.4 percent. Perhaps 2020 will be different, as we already have an over — albeit a narrow one — in the books after Thursday’s game.

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Tennessee Titans at Denver Broncos odds, picks and best bets

Previewing the Tennessee Titans at Denver Broncos Week 1 betting odds and lines, with NFL betting picks, tips and best bets.

The Tennessee Titans and Denver Broncos begin their 2020 regular seasons at Empower Field at Mile High in Denver on Monday at 10:10 p.m. ET (on ESPN). Below, we preview the Titans-Broncos betting odds and lines and make our NFL picks and best bets.

Titans at Broncos betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 1:40 p.m.

  • Moneyline: Titans -154 (bet $154, win $100) | Broncos +130 (Bet $100, win $130)
  • Against the Spread/ATS: Titans -3 (-110) | Broncos +3 (-110)
  • Over/Under: 40.5 (O: -110, U: -110)

Special Colorado Week 1 Promotion: Place any $1 bet on the Denver Broncos, receive $100 credit for free bets into your account! Regardless of your bet outcome, you win! Place your legal, online wagers in Colorado at BetMGM. Terms and conditions apply. Bet now!

Titans at Broncos game notes

  • The Titans qualified for the playoffs in 2019, going 9-7 with a 7-5 record against AFC teams. They were 8-7-1 against the spread with 10 over results in 16 regular-season games.
  • The Broncos managed a 7-9 record with a 5-3 mark at home in 2019, while going 9-7 ATS with seven over results in their 16 regular-season battles.
  • The Titans turned the keys over to QB Ryan Tannehill after the first month of the 2019 season, and he threw for 2,742 yards, 22 touchdowns and just six interceptions in his 12 games (10 starts). He also rushed for 185 yards and four scores.
  • The Broncos have a new workhorse in the backfield, as RB Melvin Gordon comes over from the division-rival Chargers. He faced the Titans last season as a member of the Bolts, rushing for just 32 yards on 16 carries.
  • The Titans lost 16-0 to the Broncos on the road last season in Week 6. Tannehill took over for Marcus Mariota with 4:56 left in the third quarter and he never looked back.

Titans at Broncos key injuries

Titans

  • RB Darrynton Evans (hamstring) questionable
  • CB Adoree’ Jackson (knee) questionable

Broncos

  • WR KJ Hamler (hamstring) questionable
  • LB Von Miller (ankle) out
  • WR Courtland Sutton (shoulder) questionable

Titans at Broncos: Odds, betting lines, picks and prediction

Prediction

Titans 24, Broncos 16

Moneyline (?)

The TITANS (-154) aren’t a bad play on the moneyline if you don’t want to risk laying the points on the road. My personal rule of thumb is betting moneylines -180 or lower. Anything higher than that is just too much risk.

Against the Spread (?)

The TITANS (-3, -110) are favored by a field goal on the road, as they look for revenge after last season’s embarrassing shutout loss in the Mile High City last season. That game changed the course of the season for the Titans, as head coach Mike Vrabel changed his signal caller and it proved to be the move of the season. The Titans are just healthier than the Broncos in this one. Not having Miller is bad news for the Broncos, as they try to corral RB Derrick Henry. With Hamler and Sutton also nursing hamstring injuries, QB Drew Lock might have fewer speedy targets to choose from.

Over/Under (?)

O/U (40.5) is the total, and it’s too close for comfort. I expect a total of 40 points in this one. The over has cashed in four straight Monday appearances for the Titans, and the over is 6-1 in their past seven as a favorite. The over is 8-2 in Denver’s past 10 season openers, but the under is 5-2 in their past seven appearances on Monday, and 15-6-1 in the past 22 as an underdog. AVOID.

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Miami Dolphins at New England Patriots odds, picks and best bets

Previewing the Week 1 matchup between the New England Patriots and Miami Dolphins betting odds and lines, with NFL betting picks, tips and best bets.

The new-look New England Patriots take the field Sunday at 1 p.m. ET as they play host to the Miami Dolphins in the season opener for both teams. QB Tom Brady is no longer in the picture and QB Cam Newton, a mid-summer addition, takes over as QB1 for head coach Bill Belichick and company. Let’s analyze the Patriots-Dolphins odds, lines and spread as we make our Week 1 NFL wagers and best bets around this AFC East matchup.

Dolphins at Patriots betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 1 p.m. ET.

  • Moneyline: Dolphins +270 (bet $100, win $270) | Patriots -334 (bet $334, win $100)
  • Against the Spread/ATS: Dolphins +7 (-110) | Patriots -7 (-110)
  • Over/Under: 41.5 (O: -110, U: -110)

Week 1 Special Promotion! Bet $1 on any Week 1 moneyline, WIN $100 (in free bets) if ANY team scores a touchdown. Easy win. Place your legal, online bets in CO, IN, NJ and WV at BetMGM. Terms and conditions apply. Bet now!

Dolphins at Patriots game notes

  • The Patriots have had their struggles vs. the Dolphins, splitting the series each of the past three seasons.
  • When the Patriots have won, they’ve won big — averaging 38.7 points to the Dolphins’ eight in those wins.
  • When they’ve lost, they have often been close games, including their 27-24 loss to Miami last December. In Miami’s three wins, they’ve averaged 29.3 points to the Patriots’ 25.7.
  • Is Newton back to 100% health? Newton hasn’t played a game since 9/12/2019; he had two shoulder surgeries in two years at that point and then needed surgery to repair a Lisfranc (foot) injury.
  • Dolphins QB Ryan Fitzpatrick opens the season under center; but he’s keeping the spot warm for rookie Tua Tagovailoa.
  • How good will the New England D be? The unit lost a number of key players during the offseason to free agency, while others opted out of the year due to COVID-19. 2019 NFL Defensive Player of the Year Stephon Gilmore is still manning one of the cornerback spots for the Pats, however.

Dolphins at Patriots key injuries

Miami Dolphins

  • S Clayton Fejedelem (pectoral) doubtful

New England Patriots

  • WR N’Keal Harry (shoulder) questionable
  • DE Chase Winovich (shoulder) questionable

Dolphins at Patriots: Odds, betting lines, picks and prediction

Prediction

Patriots 30, Dolphins 13

Moneyline (?)

If I was confident enough in Miami, the +270 (bet $100, win $270) on the moneyline is very attractive. In the last 11 matchups, the Patriots are 10-1 at home vs. Miami. The Patriots at -334 (bet $334, win $100) just isn’t worth a wager here, as the risk is too high for too little return profit. PASS on the moneyline.

Against the Spread (?)

When I first saw this line, I was leaning Miami (+7) to cover.

But in examining things further, even with the changes New England has dealt with, Belichick and Josh McDaniels will have this offense ready. Miami, on the other hand, is still in full rebuild. As noted earlier, when the Patriots have won lately vs. Miami, it’s usually by a wide margin. An offseason of being told the dynasty is dead and they are no longer the cream of the crop in the AFC East is just the motivation the Patriots need to set tone. PATRIOTS -7 (-110) is the play here. For every $10 wagered on the Patriots to cover, you profit $9.09 should they win by at least eight points.

Over/Under (?)

A 41.5-point line here is worth a small-unit play. It’s one of the lower ones for the week’s slate, and these two teams have hit the Over in their last eight matchups. Take the OVER (-110).

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Indianapolis Colts at Jacksonville Jaguars odds, picks and best bets

Previewing the Week 1 matchup between the Indianapolis Colts and Jacksonville Jaguars with betting odds and lines, with NFL betting picks, tips and best bets.

The first NFL Sunday begins at 1 p.m. ET, and the Indianapolis Colts kick off their season on the road against the Jacksonville Jaguars at TIAA Bank Field in of the day’s early games.

Colts at Jaguars betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 1 p.m. ET.

  • Moneyline: Jaguars +350 (bet $100, win $350) | Colts -455 (Bet $455, win $100)
  • Against the Spread/ATS: Jaguars +8.5 (-110) | Colts -8.5 (-110)
  • Over/Under: 44.5 (O: -110, U: -110)

Special Indiana Week 1 Promotion! Bet $1 on the Colts moneyline, WIN $100 (in free bets) if the Colts score a touchdown vs. Jacksonville. Regardless of the game outcome, you win! Place your legal, online bets in Indiana at BetMGM. Terms and conditions apply. Bet now!

Colts at Jaguars game notes

    • This will be QB Philip Rivers‘ debut with the Colts after playing his entire career with the Chargers.
    • The Jaguars shed payroll on defense, most notably parting ways with DE Calais Campbell and DE Yannick Ngakoue.
    • The Colts have lost six straight season openers.
    • Rivers is 7-2 in his career against the Jaguars.
    • Jacksonville is 4-2 against the Colts since the start of the 2017 season.

Colts at Jaguars key injuries

Colts

  • Julian Blackmon (knee) out
  • LB Matthew Adams (ankle) questionable

Jaguars

  • TE Tyler Davis (knee) out

Colts at Jaguars: Odds, betting lines, picks and prediction

Prediction

Colts 27, Jaguars 16

Moneyline (?)

The Colts are such large favorites that you are going to have to bet more than four times what you want to win. The Jaguars have shed talent on both sides of the ball and appear to be trying to rebuild, while the Colts should be competing with the addition of Rivers. If you feel like you have to bet the money line, take the Colts, but the best bet here is to AVOID because there is just no value.

Against the Spread (?)

Neither team was a particularly good bet last year. The Colts went 7-9 overall and were 7-7-2 ATS, while the 6-10 Jags were 7-9 ATS. Despite the Colts’ addition of Rivers and the Jaguars’ loss of most of their best defensive players, this game won’t be a huge blowout — but it should be by a large enough margin for the Colts to cover. Take the COLTS -8.5 (-110).

Stay up to speed:

Over/Under (?)

Both teams were not heavy on one side or the other in 2019. It will come down to how many points the Jaguars can score without Leonard Fournette (also let go) against a talented Colts defense. If Jacksonville can’t get to 20 points (I don’t think they can), the under should hit. Take the UNDER 44.5 POINTS (-110).

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Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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Tampa Bay Buccaneers at New Orleans Saints odds, picks and best bets

Previewing the Tampa Bay Buccaneers and New Orleans Saints Week 1 betting odds and lines, with NFL betting picks, tips and best bets.

QB Tom Brady and the new-look Tampa Bay Buccaneers will begin their 2020 campaign Sunday afternoon against the New Orleans Saints Sunday of Week 1. Kickoff is set for 4:25 p.m. ET. Below, we preview the Buccaneers-Saints betting odds and lines and make our NFL picks and best bets.

Buccaneers at Saints betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 2:15 p.m. ET.

  • Moneyline: Buccaneers +155 (bet $100, win $155) | Saints -182 (Bet $182, win $100)
  • Against the Spread/ATS: Buccaneers +3.5 (-110) | Saints -3.5 (-110)
  • Over/Under: 47.5 (O: -110, U: -110)

Get some action on this NFL game or others by placing a legal sports bet in CO, IN, NJ and WV at BetMGM Sportsbook. Bet now!

Buccaneers at Saints game notes

  • The Saints have beaten the Buccaneers in each of their last three meetings and in five of their last seven. Going all the way back to 2011, the Saints are 13-5 against the Bucs.
  • This will be Brady and TE Rob Gronkowski‘s first game in a uniform besides those of the New England Patriots after the two wound up in Tampa Bay this offseason via free agency and trade, respectively.
  • The Saints have better odds to win the Super Bowl, but only slightly ahead of the Buccaneers. New Orleans is +1200 (third-best), while the Buccaneers are +1400 (T-4).
  • The Buccaneers are 8-11 in Week 1 games since 2000, including a 2-4 stretch in their last six.
  • The Saints are 9-11 in their last 20 Week 1 games but have gone just 1-5 since 2014.

Buccaneers at Saints key injuries

Buccaneers

  • WR Mike Evans (hamstring) questionable

Saints

  • DE Marcus Davenport (elbow) questionable
  • OL Cesar Ruiz (ankle) questionable

Buccaneers at Saints: Odds, betting lines, picks and prediction

Prediction

Saints 24, Buccaneers 21

Moneyline (?)

The Bucs-Saints rivalry got a lot more interesting when Brady and Gronk came aboard, but it could take a little time for this team to mesh on the field – especially after a condensed offseason with no preseason games. The Saints look similar to last year’s team, which will afford them the benefit of cohesion and continuity.

The Saints are favored for a reason, even if the Superdome won’t be as loud as usual. Take the SAINTS (-182) to win outright at home over the new Brady Bunch.

Against the Spread (?)

The Saints come in as 3.5-point favorites, the third year in a row they’ve been favored in a Week 1 matchup. This isn’t the usual Bucs team they’ve faced and beaten twice in season openers before, though.

Brady will keep the score close and the Bucs defense will do enough to slow down Brees, RB Alvin Kamara and WR Michael Thomas, covering the spread down to the wire.

Take the BUCS +3.5 (-110) and stay within 3 points in a loss or win outright.

Over/Under (?)

The Over/Under is set at 47.5 points, which is about where you’d expect it to be. There will be some first-game jitters on both sides, especially after the preseason was canceled, but they’ll knock off the rust at some point during the game.

They still won’t push the total over 47.5 points, though. Both defenses are good enough to slow down the opposing offense, particularly New Orleans’. Take the UNDER 47.5 (-110).

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Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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Arizona Cardinals at San Francisco 49ers odds, picks and best bets

Previewing the Week 1 matchup between the Cardinals and 49ers, including betting odds and lines, with NFL betting picks, tips and best bets.

The San Francisco 49ers (0-0) begin their NFC West and NFC conference titles in 2020, opening the season against the Arizona Cardinals (0-0). Kickoff is at 4:25 p.m. ET at Levi’s Stadium on Sunday in front of an empty stadium.

Cardinals at 49ers betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 1:45 p.m. ET.

  • Moneyline: Cardinals +240 (bet $100, win $240) | 49ers -295 (Bet $295, win $100)
  • Against the Spread/ATS: Cardinals +6.5 (-110) | 49ers -6.5 (-110)
  • Over/Under: 48.5 (O: -110, U: -110)

Get some action on this NFL game or others by placing a legal sports bet in CO, IN, NJ and WV at BetMGM Sportsbook. Bet now!

Cardinals at 49ers game notes

  • The 49ers swept the season series in 2019.
  • Cardinals QB Kyler Murray is coming off an Offensive Rookie of the Year season in 2019.
  • The 49ers lost WR Emmanuel Sanders in free agency and traded away RB Matt Breida and DL DeForest Buckner in the offseason.
  • The Cardinals acquired WR DeAndre Hopkins via trade, re-signed RB Kenyan Drake and added DL Jordan Phillips, LB Devon Kennard, LB De’Vondre Campbell, LB Isaiah Simmons and CB Dre Kirkpatrick in the offseason.

Cardinals at 49ers key injuries

Cardinals

  • TE Maxx Williams (ankle)

49ers

  • WR Deebo Samuel (foot) doubtful
  • WR Brandon Aiyuk (hamstring) questionable
  • CB Jason Verrett (hamstring) doubtful
  • OL Ben Garland (ankle) questionable

Cardinals at 49ers: Odds, betting lines, picks and prediction

Prediction

49ers 28, Cardinals 27

Moneyline (?)

Despite playing two close games against one another in 2019 and the Cardinals making big improvements in the offseason, the 49ers remain heavy favorites in the season opener. This feels like a game that the Cardinals are in position to sneak a victory, although I am not confident enough to say put your money on them for the big payout on the money line. As for betting the Niners, the -295 is just too rich. This game could go either way so AVOID the money line.

49ers Wire: 49ers injury report: Brandon Aiyuk returns to practice

Against the Spread (?)

The Cardinals, despite being 5-10-1 straight up in 2019, were a very solid 9-5-2 ATS. The 49ers did not cover the spread in either game against Arizona last season, and the Cardinals appear to be much improved. This is bound to be one that goes down to the wire. The result will be closer than a touchdown. Take the Cardinals +6.5 (-110). 

Cardinals Wire: Cardinals to make DeAndre Hopkins highest-paid WR with extension

Over/Under (?)

These two teams blew by 50 points in their first meeting and combined for 62 points in their second contest. The Cardinals defense is better, but it is not known how much better, while their offense should put up points. This pick is easy. Pound the OVER 48.5 POINTS.

Want action on this NFL game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Follow @senorjessroot on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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