Indianapolis Colts at Jacksonville Jaguars odds, picks and best bets

Previewing the Week 1 matchup between the Indianapolis Colts and Jacksonville Jaguars with betting odds and lines, with NFL betting picks, tips and best bets.

The first NFL Sunday begins at 1 p.m. ET, and the Indianapolis Colts kick off their season on the road against the Jacksonville Jaguars at TIAA Bank Field in of the day’s early games.

Colts at Jaguars betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 1 p.m. ET.

  • Moneyline: Jaguars +350 (bet $100, win $350) | Colts -455 (Bet $455, win $100)
  • Against the Spread/ATS: Jaguars +8.5 (-110) | Colts -8.5 (-110)
  • Over/Under: 44.5 (O: -110, U: -110)

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Colts at Jaguars game notes

    • This will be QB Philip Rivers‘ debut with the Colts after playing his entire career with the Chargers.
    • The Jaguars shed payroll on defense, most notably parting ways with DE Calais Campbell and DE Yannick Ngakoue.
    • The Colts have lost six straight season openers.
    • Rivers is 7-2 in his career against the Jaguars.
    • Jacksonville is 4-2 against the Colts since the start of the 2017 season.

Colts at Jaguars key injuries

Colts

  • Julian Blackmon (knee) out
  • LB Matthew Adams (ankle) questionable

Jaguars

  • TE Tyler Davis (knee) out

Colts at Jaguars: Odds, betting lines, picks and prediction

Prediction

Colts 27, Jaguars 16

Moneyline (?)

The Colts are such large favorites that you are going to have to bet more than four times what you want to win. The Jaguars have shed talent on both sides of the ball and appear to be trying to rebuild, while the Colts should be competing with the addition of Rivers. If you feel like you have to bet the money line, take the Colts, but the best bet here is to AVOID because there is just no value.

Against the Spread (?)

Neither team was a particularly good bet last year. The Colts went 7-9 overall and were 7-7-2 ATS, while the 6-10 Jags were 7-9 ATS. Despite the Colts’ addition of Rivers and the Jaguars’ loss of most of their best defensive players, this game won’t be a huge blowout — but it should be by a large enough margin for the Colts to cover. Take the COLTS -8.5 (-110).

Stay up to speed:

Over/Under (?)

Both teams were not heavy on one side or the other in 2019. It will come down to how many points the Jaguars can score without Leonard Fournette (also let go) against a talented Colts defense. If Jacksonville can’t get to 20 points (I don’t think they can), the under should hit. Take the UNDER 44.5 POINTS (-110).

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