March Madness: Best NCAA Tournament Sweet 16 upset picks and predictions

Analyzing NCAA Tournament betting odds for the Sweet 16, with predictions and picks for the 3 best underdog bets.

The best weekend of the year is over, and now we enter the upcoming weekend with the Sweet 16 and Elite 8. Below, we break down Tipico Sportsbook’s NCAA Tournament odds and lines and list the best Sweet 16 upset bets to cash in on among SportbookWire’s expert college basketball picks and predictions.

There are 4 teams that sit outside of the top-6 seeds, No. 9 FAU, No. 15 Princeton, No. 7 Michigan State, and No. 8 Arkansas.

With No. 1 seeds like Kansas and Purdue having already fallen, fans will have all eyes on Houston and Alabama to make sure they don’t go down as well. As with every week of March Madness, expect chaos to ensue.

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NCAA Tournament Sweet 16 upset picks

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 11:08 a.m. ET. All game times ET.

FAU (+200) vs. Tennessee – Friday, 9 p.m.

Florida Atlanta ranks No. 22 in Kenpom because of its elite offense which sits 30th in adjusted rating. Its defense is also top 35. Tennessee doesn’t have a top-tier offense, but does have the No. 1-rated defense. The Owls have won 9 straight games and have scored 75 or more in 3 of their last 5.

Florida Atlanta has the offense to make noise. It ranks 50th in the nation in 3-point field-goal percentage (36.7%). It should be able to space the court and knock down shots.

With the Vols still without G Zakai Zeigler, they should start to regress defensively. At this value, back FAU (+200).

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ARKANSAS (+150) vs. UConn – Thursday, 7:15 p.m.

It seems like everyone is already counting Arkansas out. The Razorbacks have a gritty team though, having taken down No. 9 Illinois 73-63 and No. 1 Kansas 72-71. They also have wins over Kentucky and San Diego State this season. The guard play with G Ricky Council IV stepping up, especially against Kansas with 21 points, will matter against G Ryan Nembhard.

UConn is an impressive side, but the Razorbacks play at a pace, ranking 50th in adjusted tempo, that could throw the Huskies off as well. Arkansas has the 51st-best offense and 15th-best defense. It is good enough on both sides of the court to upset the No. 4 seed.

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XAVIER (+160) vs. Texas – Friday, 9:45 p.m.

The Musketeers have what it takes to pull off the upset. Xavier’s 6-foot-11 C Jack Nunge is shooting over 40% from deep for the 1st time in his career this season and can space the floor, forcing C Timmy Allen outside of the paint. Xavier has the 7th-best offense while Texas ranks 15th in offense.

Xavier ranks 5th in 3-point FG percentage (38.9%). It has the ability to run and gun. Scoring against Texas isn’t easy, but the Musketeers offense is a proven side. With wins over UConn, Creighton, Marquette, Providence and many other top-tier programs, it should be able to pull off the upset. Back XAVIER (+160).

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March Madness: Best NCAA Tournament Sweet 16 upset picks and predictions

Assessing college basketball betting odds and lines for the NCAA Tournament’s Sweet 16, with predictions and picks for the 3 best underdog bets.

With the first weekend of March Madness behind us, it’s time to prepare for the Sweet 16 and Elite Eight tipping off Thursday through Sunday.

After looking at NCAA Tournament odds and lines, here are the best Sweet 16 upset picks among our expert college basketball picks, predictions and bets.

Thursday and Friday could be a couple of the season’s most exciting days as the Sweet 16 takes place. With all eyes set on who will make the trip to New Orleans for the Final Four, fans and bettors should be laser focused on which underdogs could continue their NCAA Championship dreams.

For the Sweet 16, there are three No. 1 seeds still remaining in Gonzaga, Arizona and Kansas, which rank 1-3 in the Ferris Mowers Coaches Poll powered by USA TODAY Sports, respectively.

Defending champion Baylor is the lone No. 1 seed that didn’t make it to the Sweet 16. Plus, two No. 2 seeds – Auburn and Kentucky – went down in the second and first round, respectively.

With that in mind, fans should prepare for some more chaos as the Sweet 16 tips off Thursday at 7:09 p.m. ET.

NCAA Tournament Sweet 16 upset picks

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 8:26 p.m. ET.

Duke +1.5 (-122) vs. Texas Tech – Thursday, 9:39 p.m. ET

Duke might be the higher seed as a No. 2, but it is still underdogs in its Sweet 16 battle with third-seeded Texas Tech.

Tech’s dominant defense ranks No. 1 in adjusted-defensive efficiency per KenPom. If there’s any team able to best the Red Raiders, it’s the well-coached Blue Devils who sit fourth in adjusted-offensive efficiency.

Duke ranks 42nd in opponents’ effective field-goal rate and 10th in eFG%. It is also playing its best basketball, taking down head coach Tom Izzo and the Michigan State Spartans in the second round.

It’s understandable to favor the defensive-minded Red Raiders, but scoring can win games as well, and the Blue Devils will have the most versatile player on the court in F Paolo Banchero.

Couple that with the fact that Duke went to Notre Dame, a team Texas Tech struggled with in its second-round matchup, and beat the Fighting Irish by 14 earlier in the season, and I think the Blue Devils come out on top in this one.

I could see playing the Blue Devils’ -105 money line instead of taking the 1.5 points to avoid the extra juice.

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Houston +1.5 (-107) vs. Arizona – Thursday, 9:59 p.m. ET

The Houston Cougars, one of the most underrated teams coming into the tourney, match up very well against Arizona’s weaknesses.

In its second-round battle with TCU, Arizona gave up 20 offensive rebounds. Houston is the No. 1 team in the nation in offensive rebounding rate. It’s going to abuse Arizona on the boards in this one.

Also, Houston is among the mere two programs in the nation that rank top 10 in both offensive and defensive efficiency, per KenPom.

Much like Baylor from a year ago, the Cougars are a defense-first bunch. Houston will make life very difficult for Arizona star G Bennedict Mathurin, who averaged 24.0 points per game through the first two rounds.

Providence +7.5 (-112) vs. Kansas – Friday, 7:29 p.m. ET

The Providence Friars rank No. 1 in KenPom’s luck factor, probably a good a reason why they weren’t heavily bet on in their opening two games. This time around, let’s look at that in a different light.

The Friars are 4-0 ATS when 5-point or greater underdogs. They might be lucky, but they keep games close.

They’re also a complete team with both playmaking guards and a high-efficiency big man in C Nate Watson. They’re actually 3-1 straight up when giving that type of spread.

The Jayhawks are 5-4 ATS over their last nine outings, failing to cover recently against Creighton as 13.5-point favorites in a 79-72 second-round victory. Against a well-balanced Providence team, I expect an even closer game.

Also, the Friars are playing at a high level, crushing Richmond (79-51) – which took down Iowa in the first round – and beating South Dakota State by 9 in their opener.

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