First look: Missouri at Kentucky odds and lines, Wildcats favored in SEC opener

Previewing the college football Week 1 matchup between the Missouri Tigers and Kentucky Wildcats with odds, trends and head-to-head records.

The Missouri Tigers (1-0) and Kentucky Wildcats (1-0) meet Saturday at Kroger Field in Lexington, Ky. Kickoff is scheduled for 7:30 p.m. ET. Below, we look at the Missouri vs. Kentucky odds and lines; check back for our college football picks and predictions.

Mizzou fell behind 14-7 midway through the second quarter against Central Michigan, but the Tigers scored 10 points to take a 17-14 lead at half. The Tigers ended up posting 211 rushing yards and 257 passing yards.

The Wildcats actually trailed 7-0 early in the first quarter against UL Monroe, but Kentucky scored the next 38 points, and ended up with a 45-10 rout. Kentucky passed for 419 yards and ran for 145 yards. It wasn’t all perfect as they were actually minus-3 in the turnover department.

Missouri at Kentucky odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 1:20 p.m. ET.

  • Money line: Missouri +170 (bet $100 to win $170) | Kentucky -210 (bet $210 to win $100)
  • Against the spread/ATS: Missouri +4.5, -110 (bet $110 to win $100) | Kentucky -4.5, -110 (bet $110 to win $100)
  • Total (Over/Under): Over 52.5, -110 (bet $110 to win $100) | Under 52.5, -110 (bet $110 to win $100)

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2020 betting stats (regular season):

  • ML: Missouri 5-5 | Kentucky 4-6
  • ATS: Missouri 5-5-0 | Kentucky 4-5-1
  • O/U: Missouri 5-5-0 | Kentucky 4-6-0

Missouri at Kentucky head-to-head

These two SEC East teams face each other every season. Kentucky leads the series 7-4. However, the Tigers won 20-10 last season in Columbia, Mo., snapping a five-game win streak in the series by Big Blue.

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