Best NFL underdog picks and predictions for Week 7

Analyzing NFL Week 7 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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In Week 6, there were some big underdog wins. However, overall, it wasn’t that great a week. Only 5 underdogs covered the spread and only 4 picked out outright wins. The 2 big underdog wins were the Cleveland Browns beating the San Francisco 49ers and New York Jets taking down the Philadelphia Eagles, knocking off the last 2 undefeated teams.

Below, we analyze BetMGM Sportsbook NFL odds and lines, and tab the best NFL Week 7 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

Last week, my underdog picks went 2-1, as the Washington Commanders beat the Atlanta Falcons 24-16, the Houston Texans knocked off the New Orleans Saints 20-13, but the Chicago Bears lost 19-13 to the Minnesota Vikings. 

Through 6 weeks, I am 11-7 with my selections.

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NFL underdog predictions: Week 7

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:45 a.m. ET. All games Sunday and ET unless noted.

JAGUARS (+110) at Saints – Thursday, 8:15 p.m. (Amazon Prime)

Jaguars QB Trevor Lawrence should be good to go despite being questionable with a knee injury. Jacksonville has won 3 games in a row, while the Saints have dropped 3 of 4. The Saints are hurting on the offensive line, missing both starting tackles, and the Jaguars lead the NFL in takeaways.

The Jags are 1-1 this season as the underdog, losing only to the world-champion Kansas City Chiefs.

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CHARGERS +5.5 (-110) at Chiefs – 4:25 p.m. (CBS)

The Chiefs are 4-2 ATS on the season and 4 of their 5 wins have been by at least a TD. However, the Chargers have not lost a game by more than 3 points this season.

The Chiefs won both matchups last season but the Chargers covered the spread, losing by 3 in both games. The Chargers are 5-1 ATS against the Chiefs in their last 6 meetings.

49ers at VIKINGS +6.5 (-105) – Monday, 8:15 p.m. (ABC/ESPN)

The 49ers are coming off their 1st loss of the season and could be without LT Trent Williams, WR Deebo Samuel and RB Christian McCaffrey. 

Three of the Vikings’ 4 losses have been by 6 or fewer points. The one other loss was only by 7. The Vikings are winless at home this season, so this could be a sneaky pick to win outright, but San Francisco has been too good to predict a loss.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Vikings vs. 49ers: Everything we know

The Vikings fail to make it three in a row.

The Vikings defense faced adversity on Sunday.

The unit dealt with the losses of every starter on the defensive line. LB Anthony Barr’s hamstring injury during the game made the defense’s job even harder.

The missing pieces were easy to see. San Francisco punished the Minnesota defensive front with 208 rushing yards on the day.

The Vikings defense couldn’t stop the 49ers on offense for most of Week 12, but the team got a lucky break when San Francisco K Robbie Gould missed a 42-yard field goal to keep the Vikings within eight points late in the fourth quarter. In the end, the Vikings offense failed to convert on fourth down during its final offensive drive.

Like all of Minnesota’s losses this year, the game was close, but all the more disappointing because of it. The Vikings moved to 5-6 and their two-game win streak snapped.

Behind Enemy Lines: Previewing the Vikings’ game vs. the 49ers

Vikings fans, it’s game day. We previewed the matchup with Niners Wire:

The Vikings and 49ers are on similar trajectories.

Minnesota got back to .500 after two consecutive upset victories. San Francisco did the same thing to get to 5-5.

Barring a tie, one of these teams will continue its winning streak and add more flame to the playoff conversation fire.

We previewed the matchup with Kyle Madson of Niners Wire: