Best NFL underdog picks and predictions for Week 7

Analyzing NFL Week 7 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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In Week 6, there were some big underdog wins. However, overall, it wasn’t that great a week. Only 5 underdogs covered the spread and only 4 picked out outright wins. The 2 big underdog wins were the Cleveland Browns beating the San Francisco 49ers and New York Jets taking down the Philadelphia Eagles, knocking off the last 2 undefeated teams.

Below, we analyze BetMGM Sportsbook NFL odds and lines, and tab the best NFL Week 7 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

Last week, my underdog picks went 2-1, as the Washington Commanders beat the Atlanta Falcons 24-16, the Houston Texans knocked off the New Orleans Saints 20-13, but the Chicago Bears lost 19-13 to the Minnesota Vikings. 

Through 6 weeks, I am 11-7 with my selections.

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NFL underdog predictions: Week 7

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:45 a.m. ET. All games Sunday and ET unless noted.

JAGUARS (+110) at Saints – Thursday, 8:15 p.m. (Amazon Prime)

Jaguars QB Trevor Lawrence should be good to go despite being questionable with a knee injury. Jacksonville has won 3 games in a row, while the Saints have dropped 3 of 4. The Saints are hurting on the offensive line, missing both starting tackles, and the Jaguars lead the NFL in takeaways.

The Jags are 1-1 this season as the underdog, losing only to the world-champion Kansas City Chiefs.

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CHARGERS +5.5 (-110) at Chiefs – 4:25 p.m. (CBS)

The Chiefs are 4-2 ATS on the season and 4 of their 5 wins have been by at least a TD. However, the Chargers have not lost a game by more than 3 points this season.

The Chiefs won both matchups last season but the Chargers covered the spread, losing by 3 in both games. The Chargers are 5-1 ATS against the Chiefs in their last 6 meetings.

49ers at VIKINGS +6.5 (-105) – Monday, 8:15 p.m. (ABC/ESPN)

The 49ers are coming off their 1st loss of the season and could be without LT Trent Williams, WR Deebo Samuel and RB Christian McCaffrey. 

Three of the Vikings’ 4 losses have been by 6 or fewer points. The one other loss was only by 7. The Vikings are winless at home this season, so this could be a sneaky pick to win outright, but San Francisco has been too good to predict a loss.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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