LSU at South Carolina odds, picks and predictions

Analyzing Saturday’s LSU at South Carolina odds and lines, with college football expert picks, predictions and best bets.

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The LSU Tigers (1-1, 0-0 SEC) visit the South Carolina Gamecocks (2-0, 1-0) Saturday. Kickoff from Williams-Brice Stadium is scheduled for noon ET (ABC / ESPN+). Let’s analyze BetMGM Sportsbook’s college football odds around LSU vs. South Carolina odds, and make our expert college football picks and predictions.

LSU is No. 17 in the US LBM Coaches Poll. The Tigers fell to current-No. 11 USC in a Week 1 neutral-site test and then downed FCS Nicholls State in Week 2. Louisiana State has gotten two 300-yard passing games from QB Garrett Nussmeier.

South Carolina needed a late, short-field touchdown to edge Old Dominion in Week 1. The Gamecocks rebounded with a resounding 31-6 triumph over Kentucky Sept. 7.

US LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

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LSU at South Carolina odds

Provided by BetMGM Sportsbook ; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 1:05 p.m. ET.

  • Moneyline: LSU -275 (bet $275 to win $100) | South Carolina +220 (bet $100 to win $220)
  • Against the spread (ATS): LSU -7 (+100) | South Carolina +7 (-120)
  • Over/Under (O/U): 48 (O: -110 | U: -110)

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LSU at South Carolina picks and predictions

Prediction

LSU 31, South Carolina 21

Moneyline

PASS: Look for the spread to provide more leverage on an LSU lean.

Against the spread

Dating back to last season, LSU has lost 3 in a row ATS, and that may have bettors being too cautious with the Tigers. USC is coming off an impressive win over UK, but the Gamecocks have some fluky analytics support numbers so far and they figure to be overrated.

South Carolina has been leaky in allowing chunk plays in the passing game. LSU should have a solid edge in preventing havoc plays and in converting deep drives into 7-point posts on the scoreboard.

Give the Tigers a talent edge and a slight overall edge as they look to cover on the LSU -7 (+100) action.

Over/Under

The total has gone Over in 17 of Louisiana State’s last 19 games, and that includes 5 straight on the road.

On a good-weather day, look for some big-play exchange and for LSU to be in some style-points mode late. TAKE THE OVER 48 (-110).

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