The Los Angeles Chargers (5-5) are on the road for the 3rd time in 4 weeks as they visit the Arizona Cardinals (4-7) Sunday. Kickoff is scheduled for 4:05 p.m. ET at State Farm Stadium in Glendale (CBS). Below, we look at Chargers vs. Cardinals odds from Tipico Sportsbook; check back for all our NFL picks and predictions.
The Chargers suffered a 30-27 defeat to the Kansas City Chiefs as 5.5-point home underdogs in Week 11. Chiefs QB Patrick Mahomes threw 3 TDs, including the game-winning 17-yarder to TE Travis Kelce with 31 seconds to go.
The Cardinals were blown out by the San Francisco 49ers 38-10 as 10-point underdogs in Mexico City Monday night. They allowed 159 rushing yards and 49ers QB Jimmy Garoppolo threw 4 TDs.
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Chargers at Cardinals odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 1:47 a.m. ET.
- Moneyline (ML): Chargers -200 (bet $200 to win $100) | Cardinals +170 (bet $100 to win $170)
- Against the spread (ATS): Chargers -3.5 (-107) | Cardinals +3.5 (-113)
- Over/Under (O/U): 47 (O: -114 | U: -106)
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2022 betting stats
- ML: Chargers 5-5 | Cardinals 4-7
- ATS: Chargers 7-3 | Cardinals 5-6
- O/U: Chargers 5-5 | Cardinals 6-5
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Chargers vs. Cardinals head-to-head
The Cardinals and Chargers rarely play each other in the regular season. They have only had 14 matchups dating back to 1971.
The Chargers are 10-4 against the Cardinals and have won 4 of the last 5 meetings.
They last met in 2018, a 45-10 Chargers win in Los Angeles.
Neither Cardinals QB Kyler Murray nor Chargers QB Justin Herbert have faced the other team in their careers.
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