LA Rams predictions spread over/under betting line

LA Rams at San Francisco 49ers odds, picks and predictions

Analyzing LA Rams at San Francisco 49ers odds and lines, with expert NFL picks and predictions.

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The LA Rams (7-6) and San Francisco 49ers (6-7) will meet for the second time this season on Thursday night for a pivotal Week 15 game at Levi’s Stadium in Santa Clara. Kickoff is set for 8:15 p.m. ET (Prime Video). Let’s analyze BetMGM Sportsbook’s NFL odds around the Rams vs. 49ers odds, and make our expert NFL picks and predictions.

The Rams beat the 49ers 27-24 in Week 3 as a 6-point road underdog as the Over 44.5 cashed.

The Rams crept above .500 for the first time this season when they beat the Buffalo Bills 44-42 as 3.5-point underdogs on Sunday. It was the highest-scoring game of the season, featuring 12 total TDs, 902 yards and 0 turnovers. Los Angeles has won 2 straight games and is second in the NFC West.

The 49ers also came away with a win in Week 14, steamrolling the Chicago Bears at home 38-13. The 49ers had 452 total yards of offense compared to only 162 for the Bears, a dominant victory from start to finish. The 49ers are still 2 games back of the Seahawks for the division lead, but a win will keep them in the mix for another division title.

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Rams at 49ers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Wednesday at 2:37 p.m. ET.

Moneyline (ML): Rams +130 (bet $100 to win $130) | 49ers -155 (bet $155 to win $100)
Against the spread (ATS): Rams +3 (-120) | 49ers -3 (+100)
Over/Under (O/U): 49.5 (O: -110 | U: -110)

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Rams at 49ers key injuries

Rams

CB Cobie Durant (chest) questionable
C Beaux Limmer (knee) questionable
WR Demarcus Robinson (shoulder) questionable

49ers

DE Nick Bosa (hip/oblique) questionable
RB Isaac Guerendo (foot) questionable
OT Trent Williams (ankle) questionable
LB Dre Greenlaw (Achilles) questionable

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Rams at 49ers picks and predictions

Prediction

Rams 27, 49ers 24

Moneyline

The Rams already beat the 49ers once this year and now they’re going for the season sweep of their rivals. Their win over the Bills on Sunday was far more impressive than San Francisco’s victory against the Bears, even if it was only by 2 points.

The offense is just about fully healthy, which will be a problem for the 49ers’ banged-up defense. And with San Francisco down to either its third- or fourth-string running back, a rushing attack that’s given the Rams fits over the years will be shorthanded.

With QB Matthew Stafford playing lights out in recent weeks, the Rams will take down their rival on the road Thursday. BET RAMS (+130) to win outright.

Against the spread

With the spread sitting at the key number of +3, it’s not a bad idea to sprinkle a bit on the Rams to cover just in case they lose a close one to the 49ers. However, I’d rather just play the ML and bet Los Angeles to win its third straight game.

LEAN RAMS +3 (-120).

Over/Under

The Rams nearly went over the total by themselves last week against the Bills, putting up 44 points on their own. Their defense has struggled to stop anyone in recent weeks, giving up 560 rushing yards in their last three games, so the 49ers should be able to score on the LA defense.

The Rams, meanwhile, seemingly found something on offense against Buffalo. And with WR Puka Nacua playing perhaps better than he ever has, the Rams’ passing attack will give the 49ers’ secondary trouble.

BET OVER 49.5 (-110).

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First look: Buffalo Bills at LA Rams odds and lines

Looking at Sunday’s Buffalo Bills at LA Rams Week 14 NFL odds, lines and trends. Here’s what you need to know.

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The Buffalo Bills (10-2) are on the road in Week 14 to face the LA Rams (6-6) at SoFi Stadium on Sunday afternoon. Kickoff is set for 4:25 p.m. ET from Inglewood, Calif. Below, we look at Bills vs. Rams odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Bills are coming off another big win on Sunday night, steamrolling the San Francisco 49ers at home 35-10 in a snow game. QB Josh Allen bolstered his MVP case with a rushing TD and 2 passing TDs – one of which went to himself thanks to an assist from WR Amari Cooper. With the win, the Bills clinched the AFC East for the fifth straight year.

The Rams also won in Week 13, taking down the New Orleans Saints 21-14 on the road. They came back from a 6-0 halftime deficit, scoring 21 points in the second half thanks to 2 TD passes by QB Matthew Stafford. The Rams are only 1 game back in the NFC West, so they’re right in the mix for a playoff spot.

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Bills at Rams odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 9:58 a.m. ET.

Moneyline (ML): Bills -200 (bet $200 to win $100) | Rams +165 (bet $100 to win $165)
Against the spread (ATS): Bills -4 (-110) | Rams +4 (-110)
Over/Under (O/U): 48.5 (O: -115 | U: -105)

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2024 betting stats

ML: Bills 10-2 | Rams 6-6
ATS: Bills 8-4 | Rams 5-7
O/U: Bills 7-4-1 | Rams 6-6

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Bills vs. Rams head-to-head

This is only the third game between the Rams and Bills since 2020, with each of their last 2 meetings being won by Buffalo. In fact, the Bills have won 3 in a row against the Rams since 2016 and have taken 4 of the last 5 meetings.

In their most recent matchup, the Bills beat the Rams 31-10 in the 2022 season opener after Los Angeles’ Super Bowl win the year prior. They easily covered the spread as 1-point favorites, though the total stayed under the line of 52 points.

The Rams’ last win against the Bills came in 2012 on the road, beating Buffalo 15-12 as 3.5-point underdogs.

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First look: LA Rams at New Orleans Saints odds and lines

Looking at Sunday’s LA Rams at New Orleans Saints Week 13 NFL odds, lines and trends. Here’s what you need to know.

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The LA Rams (5-6) will play the New Orleans Saints (4-7) in Week 13 on Sunday afternoon at the Caesers Superdome. Kickoff from New Orleans is set for 4:05 p.m. ET (FOX). Below, we look at Rams vs. Saints odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Rams clawed their way back to .500. after a 1-4 start, but have lost 2 of their last 3 games. They were embarrassed by the Philadelphia Eagles 37-20 at home on Sunday night, losing as 3-point underdogs. At 5-6, the Rams are still just 1 game out of first place in the NFC West, but their playoff chances are quickly slipping away with each loss.

The Saints had a bye in Week 12, getting a break after winning back-to-back games in the previous 2 weeks. They beat the Atlanta Falcons 20-17 in Week 10 and the Cleveland Browns 35-14 in Week 11, both after coach Dennis Allen was fired.

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Rams at Saints odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 11:24 a.m. ET.

Moneyline (ML): Rams -130 (bet $130 to win $100) | Saints (bet $100 to win $110)
Against the spread (ATS): Rams -2.5 (-110) | Saints +2.5 (-110)
Over/Under (O/U): 46.5 (O: -110 | U: -110)

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2024 betting stats

Note to writer: Use 2023 for 2024’s first game

ML: Rams 5-6 | Saints 4-7
ATS: Rams 4-7 | Saints 5-6
O/U: Rams 6-5 | Saints 7-4

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Rams vs. Saints head-to-head

Sunday’s game will be the 11th meeting between the Rams and Saints since 2010. The Rams have won 6 of their last 10 games against the Saints, including their most recent game in 2023 when they beat New Orleans, 30-22, as 4-point favorites.

The Rams are now 4-2 against the Saints since hiring Sean McVay in 2017, including a win in the NFC title game in 2018 to reach the Super Bowl.

In their 10 most recent game against the Saints dating back to 2010, the Rams are 6-4 ATS. It’s been an even split between the over and under in those games, with each hitting 5 times.

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Philadelphia Eagles at LA Rams odds, picks and predictions

Analyzing Sunday’s Philadelphia Eagles at LA Rams odds and lines, with expert NFL picks and predictions.

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The Philadelphia Eagles (8-2) will try to extend their winning streak to 7 games when they visit the LA Rams (5-5) on Sunday night in Week 12. Kickoff from SoFi Stadium in Inglewood, Calif., is set for 8:20 p.m. ET (NBC). Let’s analyze BetMGM Sportsbook’s NFL odds around the Eagles vs. Rams odds, and make our expert NFL picks and predictions.

The Eagles have won 6 in a row to grab hold of the NFC East lead over the Washington Commanders after beating them 26-18 in the Week 11 Thursday game. The Eagles rank fifth in yards per game (379.9) and first in yards allowed per game (273.1), scoring at least 26 points in each of their last five games after doing so just once in their first 5.

The Rams got back to .500 by beating the New England Patriots 28-22 in Week 11. They’ve won 4 of their last 5, with their only loss a 23-15 defeat against the Miami Dolphins in Week 10. The Rams are only 1 game back of the Arizona Cardinals for the NFC West lead.

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Eagles at Rams odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 1:43 a.m. ET.

Moneyline (ML): Eagles -155 (bet $155 to win $100) | Rams +130 (bet $100 to win $130)
Against the spread (ATS): Eagles -3 (-105) | Rams +3 (-115)
Over/Under (O/U): 49 (O: -110 | U: -110)

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Eagles at Rams key injuries

Eagles

LB Nakobe Dean (groin) probable
DE Bryce Huff (wrist) out
WR DeVonta Smith (hamstring) questionable

Rams

RG Kevin Dotson (illness) probable
CB Cobie Durant (thigh) probable
RT Rob Havenstein (ankle) questionable

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Eagles at Rams picks and predictions

Prediction

Eagles 27, Rams 20

Moneyline

PASS on the money line. Though the spread is at the key number of 3, it’s still not worth playing the Eagkes ML at -155.

Against the spread

The Eagles are 4-1 ATS in their last 5 games, and they have covered the spread in 6 of their last 7 games against the Rams. Los Angeles, meanwhile, is only 4-6 ATS, covering just twice as an underdog (vs. the San Francisco 49ers and vs. the Minnesota Vikings).

Philadelphia is hitting its stride at the right time and its run game could be a problem for the Rams’ defense. BET EAGLES -3 (-105) before it moves to -3.5.

Over/Under

The total has gone Under in 4 of the Rams’ last 6 games and despite the Eagles scoring at least 26 points in 5 straight games, the Under is still 3-2 in those contests.

The Rams offense is too inconsistent to trust right now, even after putting up 28 points against the Patriots. And with Philadelphia’s talented secondary, the Rams could struggle to throw it if they fall behind. BET UNDER 49 (-110).

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