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The LA Rams (0-1) are on the road for a divisional matchup in Week 2 facing the Arizona Cardinals (0-1). Kickoff from State Farm Stadium is at 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Rams vs. Cardinals odds, and make our expert NFL picks and predictions.
The Rams opened their season with a 26-20 OT loss at the Detroit Lions Sept. 8, failing to cover as 5.5-point underdogs. The Under (53.5) cashed.
The Cardinals lost 34-28 at the Buffalo Bills in Week 1, covering as 6.5-point underdogs. The Over (45) hit.
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Rams at Cardinals odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 2:05 p.m. ET.
- Moneyline (ML): Rams +100 (bet $100 to win $100) | Cardinals -120 (bet $120 to win $100)
- Against the spread (ATS): Rams +1 (-110) | Cardinals -1 (-110)
- Over/Under (O/U): 48 (O: -110 | U: -110)
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Rams at Cardinals key injuries
Rams
- G Steve Avila (knee) out
- TE Davis Allen (back) out
- OL Kevin Dotson (foot) questionable
- CB Cobie Durant (toe) questionable
- QB Jimmy Garoppolo (suspension) out
- TE Tyler Higbee (knee) out
- S Quentin Lake (hip) questionable
- WR Puka Nacua (knee) out
- OT Joe Noteboom (ankle) out
Cardinals
- WR Zay Jones (suspension) out
- WR Xavier Weaver (oblique) questionable
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Rams at Cardinals picks and predictions
Prediction
Cardinals 24, Rams 20
Moneyline
The Cardinals (-120) have not beaten the Rams at home in 10 years and only have 2 wins over them since 2017.
But Detroit was able to run the ball against the Rams in Week 1, and the Cardinals had a top-5 rushing offense last season, led by RB James Conner.
The Rams are down to a 3rd-string left tackle and a backup center, as Noteboom and Avila both landed on injured reserve this week along with Nacua.
It is Arizona’s home opener, which should give it a little extra juice.
The Cardinals will finally get the monkey off their back, but there are better odds with the spread.
PASS.
Against the spread
The Cardinals started the season 1-0 ATS. They built a 17-3 first-half lead last week over Buffalo, which then obliterated Miami on Thursday Night Football.
The Rams defense is not at the same level as Buffalo’s right now.
BET CARDINALS -1 (-110).
Over/Under
Between Conner and Rams RB Kyren Williams, this could be a run-heavy game, slowing down the pace.
Four of the last 5 meetings have not reached 48 total points.
BET UNDER 48 (-110).
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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