Dallas Cowboys at Los Angeles Chargers odds, picks and predictions

Analyzing Monday’s Dallas Cowboys at Los Angeles Chargers odds and lines, with expert NFL picks and predictions.

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The Los Angeles Chargers (2-2) welcome the Dallas Cowboys (3-2) to SoFi Stadium for Monday Night Football. Kickoff is set for 8:15 p.m. ET (ABC/ESPN). Below, we analyze BetMGM Sportsbook’s lines around the Cowboys vs. Chargers odds, and make our expert NFL picks and predictions.

The Chargers had a bye in Week 5. They beat the Las Vegas Raiders 24-17 in Week 4, pushing as a 7-point home favorite. They are 1-2-1 against the spread (ATS) this season and are 0-1-1 ATS at home while going 2-2 O/U. The Chargers defense has allowed 24 or more points in 3 of 4 games. QB Justin Herbert has 1,106 passing yards and 7 TDs in 4 games.

The Cowboys are coming off a discouraging 42-10 loss at the San Francisco 49ers last week. They failed to cover as a 3.5-point road underdog as the Over 45 hit. Dallas is 3-2 ATS this season and 1-2 ATS on the road. QB Dak Prescott has had his fair share of struggles so far, with 5 TDs and 4 INTs in 5 games.

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Cowboys at Chargers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 3:53 p.m. ET.

  • Moneyline (ML): Cowboys -125 (bet $125 to win $100) | Chargers +110 (bet $100 to win $110)
  • Against the spread (ATS): Cowboys -1.5 (-110) | Chargers +1.5 (-110)
  • Over/Under (O/U): 51 (O: -110 | U: -110)

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Cowboys at Chargers key injuries

Cowboys

  • LB Joey Bosa (toe)questionable
  • TE Donald Parham (wrist) questionable
  • DT Nick Williams (back) questionable

Chargers

  • CB C.J. Goodwin (pectoral) out
  • LB Leighton Vander Esch (neck/concussion) out
  • T Chuma Edoga (illness) questionable

Cowboys at Chargers picks and predictions

Prediction

Chargers 28, Cowboys 27

Moneyline

BET CHARGERS (+105).

The Chargers were 5-3 at home last season while the Cowboys were 5-5 on the road. LA is 1-1 at home, but lost 36-34 in a shootout in Week 1 against the Miami Dolphins. It has played well this season and will be taking on a defense that has given up 28 or more points in 2 of its last 3 games.

The Cowboys have struggled on defense and will be taking on a potent Herbert-led attack. The Cowboys haven’t played many quality QBs. They beat the New York Jets led by Zach Wilson, the New York Giants led by Daniel Jones, and the New England Patriots led by Mac Jones. None of that has been too impressive.

Expect the Cowboys’ defense to continue to struggle and back the CHARGERS (+105) to come out on top at home.

Against the spread

PASS.

The Cowboys haven’t beaten a team .500 or better and will struggle, so avoid the spread play on either side and back the Chargers on the ML. Dallas’ lone game against a team over .500 was a 42-10 loss against the 49ers.

Over/Under

BET OVER 51 (-110).

The Cowboys are 3-2 O/U this season and have gone north of the projected total in 3 of their last 4 games. The Chargers are 2-2 O/U and have scored at least 24 points in each battle.

Both teams have dynamic QBs and lacking defenses which should be a recipe for a fast-paced, high-scoring game. Take OVER 51 (-110).

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