Jacksonville Jaguars at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Jacksonville Jaguars at Indianapolis Colts odds and lines, with expert NFL picks and predictions.

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The Jacksonville Jaguars square off against the Indianapolis Colts Sunday in Week 1 NFL action. Kickoff from Lucas Oil Stadium is scheduled for 1 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook’s lines around the Jaguars vs. Colts odds, and make our expert NFL picks and predictions.

The Jaguars are looking to build off of a 9-8 campaign in 2022 that saw them advance to the AFC Divisional Round before losing to the Kansas City Chiefs. With the addition of WR Calvin Ridley this offseason, QB Trevor Lawrence is expected take another step forward in his 3rd season.

The Colts finished with a dismal 4-12-1 record in 2022, which led to them replacing former head coach Frank Reich with Shane Steichen from the Philadelphia Eagles. After cycling through veteran quarterbacks in recent years, Indianapolis will now give the keys to the offense to rookie 1st-round QB Anthony Richardson, who they selected 4th overall.

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Jaguars at Colts odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 9 a.m. ET.

  • Moneyline (ML): Jaguars -225 (bet $225 to win $100) | Colts +180 (bet $100 to win $180)
  • Against the spread (ATS): Jaguars  -4.5 (-110) | Colts +4.5 (-110)
  • Over/Under (O/U): 46 (O: -110 | U: -110)

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Jaguars at Colts key injuries

Jaguars

  • None

Colts

  • DT DeForest Buckner (forearm) questionable
  • LB Shaquille Leonard (concussion) questionable
  • RB Zack Moss (forearm) questionable

Jaguars at Colts picks and predictions

Prediction

Jaguars 30, Colts 20

Moneyline

The Jaguars (-225) are favored to win Sunday’s season opener, but I’ll AVOID their moneyline at the current odds and look for better value on the spread.

Against the spread

BET JAGUARS -4.5 (-110).

The Colts don’t seem to have much to look forward to this season outside the arrival of Richardson under center. Indianapolis will be without its star RB Jonathan Taylor after he was placed on the PUP list to start a season.

The Jaguars tallied a 7-2-1 record ATS in their final 10 games last season and should pick back from where they left off in Week 1.

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Over/Under

OVER 46 (-110) is how I’d wager on the total in this divisional bout as the Jaguars are poised to have an even better offense in 2023 upon adding Ridley to an already-talented receiver room.

The Colts are going to have a new-look defense that will be littered with inexperienced players, which will lead to more scoring opportunities for the Jaguars.

Meanwhile, Richardson’s rushing ability is enough to give Jacksonville’s defense a little trouble to begin the season.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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First look: Jacksonville Jaguars at Indianapolis Colts odds and lines

Looking at Sunday’s Jacksonville Jaguars at Indianapolis Colts Week 1 NFL odds, lines and trends. Here’s what you need to know.

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The Indianapolis Colts welcome the Jacksonville Jaguars to Lucas Oil Stadium Sunday in Week 1 NFL action. Kickoff between these AFC South rivals is set for 1 p.m. ET (FOX). Below, we look at Jaguars vs. Colts odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Jaguars look to build upon their 2022 playoff appearance, the franchise’s first postseason action since the 2017 season. The fanbase will have high expectations that QB Trevor Lawrence can get them back to consistently being in the postseason. Jacksonville finished 9-8 last season in head coach Doug Pederson’s first season with the organization and is a -155 favorite to capture the AFC South for a 2nd straight year.

The Colts drafted QB Anthony Richardson with the 4th-overall selection this offseason, but all eyes have been on the situation with RB Jonathan Taylor. The stud running back was involved in an offseason contract dispute and has been placed on the PUP to begin the season, missing at least 4 games before he’s able to return to action.

Richardson, from the University of Florida, has high expectations entering his rookie season, but the Colts as a franchise do not. RB Zack Moss — a prime candidate to see the bulk of the work with Taylor sidelined — has yet to return to practice following a broken arm in the summer which may leave work to RBs Deon Jackson and Evan Hull.  WR Michael Pittman Jr. returns the team’s main offensive weapon in the passing game.

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Jaguars vs. Colts odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 10:23 p.m. ET,

  • Moneyline (ML): Jaguars -225 (bet $225 to win $100) | Colts +180  (bet $100 to win $180)
  • Against the spread (ATS): Jaguars -4.5 (-110) | Colts +4.5 (-110)
  • Over/Under (O/U): 45 (O: -110 | U: -110)

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2022 betting stats

  • ML: Jaguars 10-9 | Colts 4-12-1
  • ATS: Jaguars 10-9 | Colts 6-11
  • O/U: Jaguars 9-10 | Colts 7-10

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Jaguars vs. Colts head-to-head

The Colts and Jaguars have a lengthy head-to-head history. Indianapolis leads the series 27-17; however, the Jaguars have won 9 of the last 15 meetings.

The two teams’ last matchup was in Week 6 last year, a 34-27 Colts victory. Former Colts QB Matt Ryan threw for 3 touchdowns and 389 yards as Indianapolis covered as a 1-point favorite while the Over (41.5) cashed.

The Jaguars haven’t gone to Indianapolis and come out with a win since 2017, so despite being favorites, Jacksonville has historically struggled at Lucas Oil Stadium.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Access more NFL coverage:

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