Indianapolis Colts vs. Jacksonville Jaguars odds predictions pick betting line spread

Alex’s best bet: Indianapolis Colts at Jacksonville Jaguars prediction

SportsbookWire.com’s Alex White likes a side in the Indianapolis Colts-Jacksonville Jaguars Week 5 NFL matchup.

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Alex White’s NFL Week 5 best bet involves the league’s lone winless team when the Jacksonville Jaguars (0-4) host the Indianapolis Colts (2-2) Sunday at 1 p.m. ET (CBS).

Surprisingly, Indy hasn’t won in Jacksonville since 2014, losing 8 in a row in Duval County.

The Colts are coming off back-to-back home wins and covers, recently beating the Pittsburgh Steelers 27-24 as 2.5-point underdogs. Unfortunately for Indianapolis, RB Jonathan Taylor and QB Anthony Richardson were injured during the victory.

Editor’s note: Alex made the below video before Taylor was ruled out for Sunday’s contest. Richardson is listed as doubtful. However, Alex is sticking with her best bet.

The Jaguars lost at the Houston Texans 24-20 in Week 4 though they did cover as 5.5-point underdogs. They are 2-2 against the spread this season.

For this Week 5 matchup, the Jaguars are favored by 3 (-115), per BetMGM Sportsbook’s NFL odds as of Saturday at 11:32 p.m. ET.

Listen below to why Alex is on this play.

🏈AFC South showdown🏈

Our @alexwhitee is dialed in on the Indianapolis @Colts at Jacksonville @Jaguars matchup in 💰Week 5 💰. Who do you like in this one? What is your best #NFL #bet of the week? pic.twitter.com/QNctFsw1zp

— SportsBookWire (@SportsBookWire) October 5, 2024

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Make sure to catch Alex on Sports By the Book Saturday 11 a.m.-noon ET, and Sunday through Wednesday noon-1 p.m. ET, and on Punch Lines every Monday and Wednesday 3 p.m.-4 p.m. ET — live from the South Point Sportsbook in Las Vegas. Follow @alexwhitee on Twitter/X.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow SportsbookWire on Twitter/X and like us on Facebook.

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Indianapolis Colts at Jacksonville Jaguars odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Jacksonville Jaguars odds and lines, with expert NFL picks and predictions.

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Indianapolis Colts (2-2) face the Jacksonville Jaguars (0-4) Sunday. Kickoff from EverBank Stadium is scheduled for 1 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Colts vs. Jaguars odds, and make our expert NFL picks and predictions.

Both teams enter Week 5 with big red flags. Colts QB Anthony Richardson is not living up to his preseason expectations while the entire Jags offense can say the same thing.

Jacksonville hasn’t scored more than 20 points this season and QB Trevor Lawrence hasn’t been so hot. In their matchup against the Houston Texans, he was 18for-33 for just 169 yards, and they converted 3rd down 4 times in 12 attempts. They led late in the 4th quarter and could not secure the win, falling 24-20 to drop to 0-4.

Indianapolis led the entire game against the Pittsburgh Steelers despite Richardson leaving early with a hip injury. QB Joe Flacco came in and played like he did last year, which won him the Comeback Player of the Year. WR Michael Pittman Jr. was the top receiver on the Colts with 6 catches for 113 yards, helping the Colts win 27-24.

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Colts at Jaguars odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 2:20 p.m. ET.

Moneyline (ML): Colts +140 (bet $100 to win $140) | Jaguars -165 (bet $165 to win $100)
Against the spread (ATS): Colts +3 (-105) | Jaguars -3 (-115)
Over/Under (O/U): 45.5 (O: -110 | U: -110)

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Colts at Jaguars key injuries

Colts

C Ryan Kelly (neck) questionable
CB Kenny Moore (hip) out
DE Kwity Paye (quad) out
QB Anthony Richardson (oblique) questionable
OT Braden Smith (knee) questionable
RB Jonathan Taylor (ankle) out

Jaguars

TE Evan Engram (hamstring) questionable
DE Josh Hines-Allen (concussion) questionable
LB Devin Lloyd (knee) questionable
S Darnell Savage Jr. (quad) questionable
S Daniel Thomas (hamstring) questionable

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Colts at Jaguars picks and predictions

Prediction

Colts 34, Jaguars 29

Moneyline

The Colts have started out slow, but I don’t think the Jaguars will pose much of a problem. Indianapolis posts the 6th-highest yards per pass (8 yards), while Jacksonville’s defense allows the 3rd worst (8 yards).

The Colt’s main liability is their run defense, which they rank worst in rush attempts a game (37.8). But the Jaguars don’t lean on their run game, rushing the 4th fewest times per game in the league (22).

I like the Colts at plus-money, but I will actually PASS here and opt for the spread.

Against the spread

Home favorites haven’t been as dominate this season against they spread, posting a 17-25-1 record. And with Jacksonville a favorite despite their winless record, I will take the Colts with the points, whether its Richardson or Flacco under center.

LEAN COLTS +3 (-105).

Over/Under

Both teams are under pressure to score in this game. And lucky for them, this is a perfect get-right game. The Colts lead the league in opponent yards per game (399.8) while the Jaguars are 3rd-worst (380).

On top of that their red zone defense is nearly as bad. Jacksonville allows a 75% touchdown rate in the red zone while Indianapolis is only slightly better with 69.2% red zone defense.

BET OVER 45.5 (-110).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Ethan Matthew on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

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Indianapolis Colts at Jacksonville Jaguars odds, picks and predictions

Analyzing Sunday’s Colts at Jaguars odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts (0-0-1) and Jacksonville Jaguars (0-1) continue their AFC South rivalry Sunday at TIAA Bank Field in Jacksonville, Fla. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Jaguars odds, and make our expert NFL picks and predictions.

The Colts tied the Houston Texans 20-20 in Week 1 after both squads failed to score in overtime. QB Matt Ryan had a solid day with 352 yards passing, 1 TD and 1 INT. He found WR Michael Pittman Jr. for 121 of those yards on 9 receptions. RB Jonathan Taylor continued to show why he’s the NFL’s top back, earning 161 yards and a TD on 31 carries.

The Jaguars lost on the road last week 28-22 to the Washington Commanders. Jacksonville led 22-14 in the 4th quarter, but allowed 14 unanswered points in the final 10 minutes. Second-year QB Trevor Lawrence passed for 275 yards and 1 TD and 1 INT. His favorite target was newly-acquired WR Christian Kirk, who had 6 receptions for 117 yards.

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Colts at Jaguars odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:26 a.m. ET.

Money line (ML): Colts -165 (bet $165 to win $100) | Jaguars +140 (bet $100 to win $140)
Against the spread (ATS): Colts -3.5 (+102) | Jaguars +3.5 (-125)
Over/Under (O/U): 44.5 (O: -112 | U: -108)

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Colts at Jaguars key injuries

Colts

WR Alec Pierce (concussion) out
WR Michael Pittman Jr. (quad) out
DT DeForest Buckner (hip) questionable
CB Kenny Moore II (hip) questionable

Jaguars

None

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Colts at Jaguars picks and predictions

Prediction

Jaguars 24, Colts 20

Money line

If you’re ever going to play Jacksonville as an underdog, right now may be the perfect time to do it. The Colts are already banged up just 2 weeks into the season, missing 2 of their top WRs in Pittman and Pierce. They’ll rely on the running game with Taylor, but that 1-dimensional offensive approach may not be enough to take out the Jags on the road.

I like the JAGUARS +140.

Against the spread

If you’re not quite sold on taking the Jags straight up, that’s okay. Play the JAGUARS +3.5 (-125). Both matchups from each squad last week suggest they’ll play teams close, plus this is a divisional matchup where each team will throw out its best. Recent history shows the Jags should cover as well — they’re 4-0 ATS vs. the Colts in their last 4 matchups.

Over/Under

I try to avoid over/unders on total points at the beginning of the season until teams and trends are more established. That said, if you’re dying to put something down on this, I’d lightly lean toward UNDER 44.5 (-108) for the sole fact that neither offense appears to be that good (yet). The Colts will run the ball more which means draining more clock, while the Jaguars have yet to do anything to show that their offense can consistently put up big points.

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Indianapolis Colts at Jacksonville Jaguars odds, picks and prediction

Analyzing Sunday’s Indianapolis Colts at Jacksonville Jaguars odds and lines, with expert NFL picks, predictions and best bets.

On Sunday, the Indianapolis Colts (9-7) travel to Florida to take on the Jacksonville Jaguars (2-14). Kickoff at EverBank Field is slated for 1 p.m. ET. Below, we look at the Colts vs. Jaguars odds and lines, and make our best NFL picks, predictions and bets.

The Colts are entering this game in a must-win scenario. If the Colts lose, they’re more than likely out (they could still get in with a Raiders/Chargers win and a Steelers/Ravens tie). Basically, they need to win.

Indy has been better than preseason expectations, covering 10 of its 16 games. The Jags, on the other hand, have had a fiasco of a season and have covered just 4 times this season.

Jacksonville’s star RB James Robinson has been out after sustaining a season-ending injury. With QB Trevor Lawrence set to start, the Jags have failed to cover 7 straight games including twice as double-digit underdogs.

Colts at Jaguars odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:30 a.m. ET.

Money line: Colts -1200 (bet $1200 to win $100) | Jaguars +700 (bet $100 to win $700)
Against the spread (ATS): Colts -14.5 (-108) | Jaguars +14.5 (-112)
Over/Under (O/U): 43.5 (O: -110 | U: -110)

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Colts at Jaguars key injuries

Colts

CB Xavier Rhodes (hamstring) out
DT DeForest Buckner (knee) questionable

Jaguars

TE James O’Shaughnessy (knee) out
TE Dan Arnold (knee) questionable

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Colts at Jaguars odds, lines, predictions and picks

Prediction

Colts 31, Jaguars 10

Money line

PASS on the money line. A -1200 in the NFL has no value. Similarly, the Colts are in a must-win scenario and are the far better team, giving the Jaguars +700 also little value.

Against the spread

BET on the COLTS -14.5 (-108).

While the Colts are a bona fide playoff contender, this is more a fade on the Jags. The two times in the past two months that they’ve been double-digit underdogs, they lost by 30 and 40.

With an atrocious run defense, the Colts, who have the league’s rushing yards leader in Jonathan Taylor, should be able to have their way. The Jags rank 25th in opponents’ rushing yards per game.

They also rank dead last in turnovers. Indy ranks 2nd in defensive turnovers, so it’ll more than be giving great field position a couple of times. With that in mind, I’d back the COLTS -14.5 (-108).

Over/Under

“LEAN” to the UNDER 43.5 (-110). The Jags haven’t been able to move the ball for the better part of the season, and they’ve covered the Over just 5 times.

Jacksonville ranks at the bottom of the league in points per game and will face a Colts defense that knows the stakes this game has.

With that in mind, I’d lean the Under as the Colts should heavily limit the Lawrence-led Jags.

Also see: All Week 18 odds and lines

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