NFL Wild Card: Indianapolis Colts at Buffalo Bills odds, picks and prediction

Previewing the Indianapolis Colts and Buffalo Bills NFL Wild Card betting odds and lines, with NFL betting picks, tips and predictions.

The Indianapolis Colts (11-5) and Buffalo Bills (13-3) lock horns in an AFC playoff game Saturday in NFL Wild Card Weekend at 1:05 p.m. ET at Bills Stadium. Below, we preview the Colts-Bills betting odds and lines and make our NFL picks and predictions.

Colts at Bills: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 4:04 a.m. ET.

  • Money line: Colts +230 (bet $100 to win $230) | Bills -275 (bet $275 to win $100)
  • Against the spread/ATS: Colts +6.5 (-105) | Bills -6.5 (-115)
  • Over/Under: 51.5 (O: -105 | U: -115)

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Colts at Bills: Game notes

  • The Colts enter this game having won four of their past five games outright, but they’re 0-3 ATS since their most recent cover in Week 14 in Las Vegas. Indianapolis has also scored at least 24 points in each of its past eight games.
  • Indianapolis has racked up 378.1 total yards of offense per game to rank 10th in the NFL, and they’re 11th in both passing yards (253.3) and rushing yards (124.8) per contest. The Colts rank ninth with 28.2 PPG.
  • Defensively the Colts have been stout, allowing just 332.1 total yards per game to rank eighth in the NFL, and they’re second in rushing defense with 90.5 yards per game allowed. If teams have success against their D, it’s through the air, as they have allowed 241.6 passing yards per game to check in just 20th.
  • Buffalo scored a season-high 56 points in their 30-point win over Miami in Week 17, winning for the sixth straight game, while covering for the eighth consecutive outing. They have also won five straight at home and covered four in a row in Western New York.
  • The Bills’ offense has been on point, going for 396.4 total yards per game to rank second in the NFL. They’re also second in points scored, 31.3 PPG while averaging 288.8 passing yards per game to rank third in the league. If they have an Achilles heel, it’s their run game, which generated just 107.7 rushing yards per contest.

Colts at Bills: Key injuries

Colts

  • DT DeForest Buckner (ankle) questionable
  • CB Rock Ya-Sin (concussion) out

Bills

  • WR Cole Beasley (knee) questionable
  • WR Stefon Diggs (oblique) questionable

Colts at Bills: Odds, betting lines, predictions and picks

Prediction

Bills 29, Colts 20

Money line (?)

Playing the Bills (-275) is not a good idea, risking nearly three times your potential return. Over the long haul, it’s a losing proposition to bet in that manner unless you plan to toss it into a multi-team parlay. Even then, it’s better to just bet against the spread. PASS.

Against the spread (?)

The BILLS -6.5 (-115) have been money at home, with their last non-cover coming in Week 8 against New England in a 24-21 win as four-point favorites, and their last outright loss coming in Week 10 against the Arizona Cardinals on the Hail Murray, 32-30.

Even without their throngs of fans at full throat, Bills Stadium has been a difficult place to play. They’ll have a limited amount of fans in the stands Saturday to help spur them on.

Over/Under (?)

These are a couple of high-flying offenses, and they should put on a show in the opening game of the 2020 NFL playoffs. However, the lean is to the UNDER 51.5 (-115).

In last season’s wild-card round the Under was a perfect 4-0, and the Under is hitting at a 75.8 percent clip (22-7-3) across the wild-card round in the past eight seasons. That’s good enough for me to keep banging Under plays.

Want action on this NFL game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

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Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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NFL Wild Card: Indianapolis Colts road underdogs at Buffalo Bills

The Indianapolis Colts are the betting underdogs in their NFL Wild Card game at the Buffalo Bills.

The first of six NFL Wild Card Weekend games pits the Indianapolis Colts (11-5) at the Buffalo Bills (13-3) Saturday in an AFC Wild Card matchup. Kickoff is at 1:05 p.m. ET at Bills Stadium in Orchard Park, N.Y. Below, we take a look at the early Colts-Bills betting odds and lines at BetMGM Sportsbook.

The Colts needed a win in Week 17 and a loss from either the Miami Dolphins, Baltimore Ravens, Tennessee Titans or Cleveland Browns to make the postseason. The Colts picked up a 28-14 win over the Jacksonville Jaguars and the Dolphins lost, so the Colts qualified as the AFC’s No. 7 seed. Rookie RB Jonathan Taylor was the star Sunday, rushing for 253 yards and two touchdowns vs. the Jaguars.

The Bills aided the Colts, defeating the Dolphins 56-26 for their 13th win of the season. QB Josh Allen threw three touchdown passes and the defense intercepted Miami QB Tua Tagovailoa three times.

Colts at Bills betting odds, spread and line

Odds via BetMGM; last updated Monday at 6:24 p.m. ET. 

  • Money line: Colts +250 (bet $100 to win $250) / Bills -300 (bet $300 to win $100) | Bet now
  • Against the spread: Colts +7, -110 (bet $110 to win $100) / Bills -7, -110 (bet $110 to win $100) | Bet now
  • Total: 51.5, Over -115 (bet $115 to win $100) / Under -105 (bet $106 to win $100) | Bet now

New to NFL betting?

The Colts, at +250 odds, have an implied 28.57% chance of winning, or 5/2 fractional odds. If Indy wins outright or loses by less than a touchdown, a Colts +7 (-110) bet wins. A 7-point loss is a push and you get your money back.

Place your legal, online NFL bets in CO, IA, IN, NJ, PA, TN and WV at BetMGM. Risk-free first bet! Terms and conditions apply. Bet now!

At -300 odds, the Bills have an implied 75% chance of beating the Colts or 1/3 fractional odds. Buffalo must win by 8 or more points for a Bills -7 (-110) ATS ticket to cash.

Also see:

Get some action on this NFL game or others by signing up and betting at BetMGM. If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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