First look: Philadelphia Eagles at Detroit Lions odds and lines

Looking at Sunday’s Philadelphia Eagles at Detroit Lions Week 1 NFL odds, lines and trends. Here’s what you need to know.

The Philadelphia Eagles and the Detroit Lions open their regular season in a Week 1 matchup Sunday at Ford Field in Detroit. Kickoff on Sept. 11 is scheduled for 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Eagles at Lions odds and lines; check back for our NFL picks and predictions.

The Eagles were annihilated in the preseason finale by the Miami Dolphins 48-10. And while a lot of stock cannot be put into preseason performances, the defense did allow 20 or more points in each of its 3 games, as the Over went a perfect 3-0.

The Lions had some hard knocks during the preseason, going 1-2 SU and 0-2-1 ATS while allowing 26 or more points in 2 of the 3 outings. The Over went 2-1 in the preseason for Detroit.

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Eagles at Lions odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Aug. 29 at 8:42 p.m. ET.

  • Money line (ML): Eagles -200 (bet $200 to win $100) | Lions +160 (bet $100 to win $160)
  • Against the spread (ATS): Eagles -3.5 (-112) | Lions +3.5 (-108)
  • Over/Under (O/U): 48.5 (O: -112 | U: -108)

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2021 betting stats:

  • ML: Eagles 9-8 | Lions 3-13-1
  • ATS: Eagles 8-8-1 | Lions 11-6
  • O/U: Eagles 10-7 | Lions 7-10

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Eagles at Lions head-to-head

Also see: All Week 1 odds and lines

These teams last met on Halloween 2021, with the Eagles blasting the Lions 44-6. Prior to that, Detroit had won 3 straight in the series, and the Lions are a healthy 5-2 ATS in the last 7 meetings. The Over has connected in an impressive 8 straight meetings.

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