March Madness: USC vs. Oregon odds, picks and prediction

Previewing Sunday’s USC vs. Oregon odds and lines, with March Madness Sweet 16 picks and predictions.

Two Pac-12 teams have made it to the Sweet 16 of the NCAA Tournament and will face off in the West Region. No. 6 seed USC Trojans (24-7) will face the No. 7 seed Oregon Ducks (21-6) Sunday night at 9:45 p.m. ET in Bankers Life Fieldhouse in Indianapolis. Below, we analyze the USC-Orgeon odds and lines, with March Madness NCAA Tournament picks and predictions.

The Trojans have cruised through the region so far, first taking down 11th-seeded Drake 72-56 and then absolutely dismantling third-seeded Kansas 85-51, holding the Jayhawks to only 29% shooting. USC held opponents to only 38.7% shooting all season, the fourth-lowest shooting percentage in the nation. They protect the basket with 5.3 blocks per game, which is the fifth-most in the nation. They are led by 7-foot freshman forward Evan Mobley‘s 16.5 points and 8.8 rebounds per game.

Oregon advanced to the Sweet 16 without having to play a first-round game. They moved on after VCU was disqualified with COVID-19 concerns on the team. But then the Ducks defeated No. 2 seed Iowa 95-80 in the second round. They shot 55.9% from the field and hit 11 three-pointers. They were the Pac-12’s best three-point shooting team this season at 39.4%. They are led by senior guard Chris Duarte‘s 17.0 points per game.

USC vs. Oregon: Odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Sunday at 1 p.m. ET.

  • Money line: USC -145 (bet $145 to win $100) | Oregon +120 (bet $100 to win $120)
  • Against the spread/ATS: USC -2.5 (-110) | Oregon +2.5 (-110)
  • Over/Under: 138.5 (O: -110 | U: -110)

March Madness betting promotions 

Current March Madness offers from BetMGM Sportsbook:

Bet $1 on any team’s money line, WIN $100 (in free bets) if ANY team hits a 3-pointer that day. Bet now!

RISK-FREE FIRST BET, up to $600! Bet now!

Offers available in CO, IA, IN, MI, NJ, PA, TN, VA and WV. New customer offers, terms and conditions apply.

USC vs. Oregon: Odds, lines, predictions and picks

Prediction

Oregon 85, USC 80

Money line (ML)

The last time the two teams matched up, USC picked up a 72-58 win, but since then the Ducks have won seven of eight games. They have split their last 10 matchups against one another, although USC holds a more recent 2-1 advantage. Oregon is scoring points in bunches and is on a roll. Their offense will overcome the Trojans’ defense. Take OREGON +120.

Play our new, free daily Pick’em Challenge and win! Play now!

Against the spread (ATS)

USC has performed better against the spread this season, going 18-13 ATS compared to Oregon’s 15-12 ATS record. However, the Ducks have covered the spread in six of their last seven games. And while the Trojans have won and covered in their two tournament games, they were 1-5 ATS in their previous six games before March Madness began. Take OREGON +2.5 (-110). 

Over/Under (O/U)

This will come down to whether Oregon’s offense or USC’s defense is stronger. The Ducks have scored 80 or more points in five of their last six games. USC has allowed under 60 in each of their first two tournament games. The Ducks’ last eight games have gone Over the total, while three of the last four for USC have gone Over as well. Take OVER 138.5 POINTS (-110). 

Want some action on this game or others? Place a bet at BetMGM now. For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

More college sports coverage from USA TODAY Sports Media Group:

Alabama / Auburn / Florida / Georgia / LSU / Michigan / Michigan State / Notre Dame / Ohio State / Oklahoma / Tennessee / Texas / USC / Wisconsin

Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1667]