UFC 281: Dominick Reyes vs. Ryan Spann odds, picks and predictions

Analyzing Saturday’s UFC 281 odds and lines between Dominick Reyes and Ryan Spann, with MMA picks, tips and predictions.

In a light heavyweight bout on the preliminary card, Dominick Reyes and Ryan Spann meet Saturday at UFC 281 at Madison Square Garden in New York. Let’s analyze Tipico Sportsbook‘s lines around the UFC 281: Reyes vs. Spann odds, and make our expert picks and predictions.

The early prelims begin at 6 p.m. ET on ESPN+, with the prelims on ESPNews/ESPN+ at 8 p.m. ET, and the main card starts at 10 p.m. ET on Pay-Per-View.

Reyes takes the walk looking to halt a 3-bout losing streak. He was knocked out in the 2nd round in the main event in May 2021 against Jiri Prochazka in his most recent appearance.

In that fight against Prochazka at UFC Vegas 25, Reyes suffered multiple injuries, including bilateral nasal bone fractures, a right displaced orbital medial wall fracture and a left displaced orbital zygomatic arch fracture.

Spann has alternated wins and losses in each of his past 5 fights, topping Ion Cutelaba last time out with a Round 1 submission. Each of his previous 4 outings has ended in the 1st round, with a win and loss by submission, and a win and loss via KO/TKO.

Spann hasn’t gone the distance since a split-decision win over “Smilin” Sam Alvey at UFC 249 on May 9, 2020. It’s his only fight in the past 7 bouts to need the judges.

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UFC 281: Reyes vs. Spann odds

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:05 a.m. ET.

  • Fight result (2-way line): Reyes -230 (bet $230 to win $100) | Spann +175 (bet $100 to win $175)
  • Over/Under: 1.5 rounds (Over -103 | Under -133)
  • Fight to go distance: Yes (+255) | No (-400)

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UFC 281: Reyes vs. Spann picks and predictions

Records: Reyes (12-3-0) | Spann (20-7-0)

Fight result (2-way line or moneyline)

The southpaw Reyes (-230) steps into the octagon with a 4.77-to-3.35 significant strikes landed per minute advantage, and he is more accurate at 51.64% to just 45.95% for Spann.

Risking more than 2 times your potential return on Reyes is a little on the expensive side. He will snap a 3-bout losing skid in this one, and he is a much better value playing REYES BY TKO/KO (+100) at even money for the method of victory.

Over/Under (O/U)

UNDER 1.5 ROUNDS (-133) is worth a look here, mainly due to the Spann factor. His past 4 fights haven’t even made it into Round 2, and 6 of his past 7 fights have cashed Under 1.5 Rounds.

Reyes will be looking to add to Spann’s misery, and he has the punching power to do so.

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