Arizona Diamondbacks at Houston Astros odds, picks and predictions

Analyzing Sunday’s Arizona Diamondbacks at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (79-64) close out their 3-game road series against the Houston Astros (77-65) Sunday night. First pitch from Minute Maid Park is at 7:10 p.m. ET (ESPN).  Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: Astros lead 2-0.

The Diamondbacks have lost 3 straight games and 7 of their last 10 overall. After getting shut out 8-0 in the series opener Friday, they lost 11-6 Saturday, the 6th time in their last 9 games they have allowed 7 or more runs.

The Astros have won 2 in a row and 7 of 10 and now have a 6-game winning streak at home.

Diamondbacks at Astros projected starters

RHP Ryne Nelson vs. RHP Justin Verlander

Nelson (10-6, 4.15 ERA) makes his 25th start and 27th appearance. He has a 1.26 WHIP, 2.0 BB/9 and 7.6 K/9 through 143 innings.

  • Last start: Win, 6 2/3 IP, 2 ER, 4 H, 2 BB, 9 K in 8-7 win at San Francisco Giants Monday
  • 5 straight starts allowing 2 or fewer ER
  • Pitched 1 inning of scoreless relief in his career vs. Houston (2023)

Verlander (3-5, 4.52 ERA) makes his 14th start. He has a 1.31 WHIP, 2.9 BB/9 and 7.9 K/9 through 71 2/3 innings.

  • Last start: Loss, 4 2/3 IP, 5 ER, 8 H, 4 BB, 3 K in 5-3 setback at Cincinnati Reds Monday
  • 0-3 with 6.75 ERA in 3 starts since returning from injured list
  • 5-1 with 1.77 ERA in 7 career starts vs. Arizona

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Astros odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:16 a.m. ET.

  • Moneyline (ML): Diamondbacks +125 (bet $100 to win $125) | Astros -155 (bet $155 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-165) | Astros -1.5 (+140)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Diamondbacks at Astros picks and predictions

Prediction

Diamondbacks 6, Astros 3

Moneyline

Verlander has struggled since his return from the injured list. The Diamondbacks are trying to not collapse at the end of the season.

They are 9-2 in Nelson’s last 11 starts. He has an ERA of 2.48 in last 5 starts.

The Diamondbacks take advantage and salvage one game of the series.

BET DIAMONDBACKS (+125).

Run line/Against the spread

The Diamondbacks are 33-15 ATS as road underdogs and 10 of their last 12 covers have been outright wins.

The Astros are 29-33 ATS as home favorites.

But the better value is the moneyline so go with that for Arizona.

PASS. 

Over/Under

Both games this series have had at least 8 total runs.

Eight of the Diamondbacks’ last 9 games have had 8 or more total runs.

Five of the last 6 for the Astros have had 8 or more total runs.

BET OVER 8 (-115).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Arizona Diamondbacks at Houston Astros odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (76-65) welcome the Arizona Diamondbacks (79-63) to Minute Maid Park Saturday. First pitch in the 2nd game of the 3-game series is set for 4:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Diamondbacks vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: Astros lead 1-0

The Diamondbacks lost 8-0 to the Astros Friday and have now dropped 2 in a row. They did win 2 of 3 games at the San Francisco Giants Tuesday through Thursday, though. Arizona is 3-6 in its last 9 despite a 40-32 road record this season. It is 74-68 against the spread (ATS).

The Astros avoided a 4-game skid with Friday’s win. They had been swept in 3 games by the Cincinnati Reds in their last series Monday through Thursday, but won 5 straight prior to the sweep. Houston is 40-29 at home this season and 72-69 ATS.

Diamondbacks at Astros projected starters

LHP Eduardo Rodriguez vs. LHP Yusei Kikuchi

Rodriguez (2-1, 5.33 ERA) makes his 6th start. He has a 1.38 WHIP, 2.5 BB/9 and 6.0 K/9 through 25 1/3 innings.

  • Last start: Loss, 4 IP, 3 ER, 7 H, 2 BB, 1 K in 11-6 home loss to LA Dodgers Monday
  • 2024 away stats: 2-0, 3.27 ERA (11 IP, 4 ER), 1.18 WHIP, 4.9 K/9 in 2 starts
  • Career vs. Astros: 1-6, 7.38 ERA (46 1/3 IP, 38 ER), 1.73 WHIP, 7.8 K/9 in 10 starts

Kikuchi (7-9, 4.24 ERA) makes his 29th start. He has a 1.25 WHIP, 2.4 BB/9 and 10.6 K/9 through 150 2/3 innings with the Astros and Toronto Blue Jays.

  • Last start: Win, 7 IP, 1 ER, 5 H, 0 BB, 12 K in 5-2 home win over Kansas City Royals Aug. 31
  • 2024 home stats: 3-7, 4.19 ERA (86 IP, 40 ER), 1.16 WHIP, 10.7 K/9 in 15 starts
  • Career vs. Diamondbacks: 0-1, 5.75 ERA (20 1/3  IP, 13 ER), 1.38 WHIP, 10.2 K/9 in 4 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Astros odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:50 a.m. ET.

  • Moneyline (ML): Diamondbacks +134 (bet $100 to win $134) | Astros -158 (bet $158 to win $100)
  • Run line (RL)/Against the spread: Diamondbacks +1.5 (-156) | Astros -1.5 (+130)
  • Over/Under (O/U): 8.5 (O: +100 | U: -122)

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Diamondbacks at Astros picks and predictions

Prediction

Astros 6, Diamondbacks 3

Moneyline

PASS.

While there is reasonable value here on both sides, the home favorite is the play; however, the odds are better played on the spread over the moneyline. Avoid this play.

Run line/Against the spread

BET ASTROS -1.5 (+130).

The Astros are 6-3 over their last 9 games, and 5 of the victories were by multiple runs. They have covered the run line in 4 of their last 5 home games. Since acquiring Kikuchi from Toronto, the Astros have won all 6 of his starts and 3 of his last 5 by multiple runs.

The Diamondbacks have lost back-to-back games overall, and Rodriguez has allowed a total of 8 runs in 9 1/3 innings over his last 2 starts. Arizona is 3-4 ATS in its last 7 games. Take ASTROS -1.5 (+130).

Over/Under

BET OVER 8.5 (+100).

Arizona has an electric offense and has gone Over in 7 of its last 8 games. The Diamondbacks have scored at least 6 runs in 6 of their last 8 games. They are 81-55-6 O/U on the season.

The Astros are the opposite at 56-80-5 O/U but have gone north of the total in 3 of their last 5 games. Considering those trends, take OVER 8.5 (+100).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Arizona Diamondbacks at Houston Astros odds, picks and predictions

Analyzing Friday’s Arizona Diamondbacks at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (75-65) welcome the Arizona Diamondbacks (79-62) to Minute Maid Park Friday to open a 3-game series. First pitch is set for 8:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Diamondbacks vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Houston won 3-0 last year

The Diamondbacks lost to the San Francisco Giants 3-2 Thursday, closing as +142 underdogs on the road. They won the series 2-1 and are 3-3 over their last 6 games. Arizona sits 3rd in the NL West and is 40-31 on the road this season. It is 4-6 over its last 10 games yet 10-6 over its last 16. The Diamondbacks are 74-67 against the spread (ATS).

The Astros were swept in 3 games at the Cincinnati Reds, wrapping up the series with a 1-0 loss Thursday. Houston, despite losing 3 straight, is 5-3 over its last 8 games and swept the Kansas City Royals in a 4-game set Aug. 29-Sept. 1. It is 39-29 at home this season and 71-69 ATS. The Astros sit atop the AL West.

Diamondbacks at Astros projected starters

RHP Brandon Pfaadt vs. LHP Frambler Valdez

Pfaadt (9-7, 4.32 ERA) makes his 28th start. He has a 1.19 WHIP, 1.9 BB/9 and 8.7 K/9 through 160 1/3 innings.

  • Last start: Win, 5 2/3 IP, 3 ER, 8 H, 2 BB, 10 K in 14-3 home victory over LA Dodgers Sunday
  • 2024 away stats: 3-4, 4.41 ERA (81 2/3 IP, 30 ER), 1.19 WHIP, 8.0 K/9 in 14 starts
  • Has never faced Astros

Valdez (13-6, 3.11 ERA) makes his 25th start. He has a 1.11 WHIP, 2.8 BB/9 and 8.7 K/9 through 150 1/3 innings.

  • Last start: No-decision, 7 IP, 0 ER, 0 H, 3 BB, 7 K in 3-2 home win over Royals Aug. 30
  • 2024 home stats: 7-2, 2.69 ERA (77 IP, 23 ER), 1.04 WHIP, 9.5 K/9 in 12 starts
  • Career vs. Diamondbacks: 0-0, 3.00 ERA (3 IP, 1 ER), 2 H, 5 BB, 3 K in 3-2 road loss in 10 innings April 13, 2022

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Astros odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:45 a.m. ET.

  • Moneyline (ML): Diamondbacks +144 (bet $100 to win $144) | Astros -172 (bet $172 to win $100)
  • Run line (RL)/Against the spread: Diamondbacks +1.5 (-150) | Astros -1.5 (+125)
  • Over/Under (O/U): 7.5 (O: -118 | U: -104)

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Diamondbacks at Astros picks and predictions

Prediction

Diamondbacks 4, Astros 3

Moneyline

BET DIAMONDBACKS (+144).

The Diamondbacks have played extremely well with Pfaadt on the mound over the last month. Arizona is 6-1 in his last 7 starts and has won 8 of its last 9 on the road overall.

Despite Valdez’s success, the Astros have scored 3 or more runs in just 3 of their last 6 games and tallied a total of 8 in their last series against the Reds.

Considering those trends and the lack of value elsewhere for a team-specific wager, take DIAMONDBACKS (+144).

Run line/Against the spread

PASS.

As road underdogs, the Diamondbacks are too expensive to take here, and the Astros are too risky as home favorites, especially considering how well Arizona plays with Pfaadt on the mound.

Over/Under

BET UNDER 7.5 (-104).

The Astros and Diamondbacks will both be starting one of their best pitchers Friday. Houston has gone Under in 4 of its last 6 games and is 55-80-5 O/U on the season. It has allowed 2 or fewer runs in 4 of its last 6 games as well.

The Diamondbacks have an electric offense but will be facing one of the best pitchers in the league. They scored just twice in their last game against the Giants. Similarly, the Astros’ cold offense could struggle to produce.

Take UNDER 7.5 (-104).

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @nathanbeighle_ on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

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