Detroit Lions at Chicago Bears odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Chicago Bears odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (12-2) visit the Chicago Bears (4-10) Sunday during NFL Week 16 action. Kickoff from Soldier Field is slated for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Lions vs. Bears odds, and make our expert NFL picks and predictions.

Detroit saw its 11-game win streak snapped Sunday when the Buffalo Bills won a 48-42 shootout. The Lions still hold the king’s spot in the NFC Playoffs picture, though.

Chicago is on its own ridiculous run, though unfortunately, it’s the other end of the spectrum with an 8-game losing streak. They most recently went into hibernation during a 30-12 loss in Week 15 to the Minnesota Vikings.

The Bears almost upset the Lions in Detroit on Thanksgiving Day but lost 23-20 on inexcusable clock mismanagement that led to the firing of then-coach Matt Eberflus.

All 4 of the Bears’ wins this year came at Soldier Field, but will they prove able to keep it close with their intradivision rivals again?

Early weather prognoses for this game typically call for temperatures below 30 degrees but cloudy, with no precipitation. Stay tuned for any changes and adjust your betting accordingly based on new information.

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Lions at Bears odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 4 p.m. ET.

  • Moneyline (ML): Lions -350 (bet $350 to win $100) | Bears +280 (bet $100 to win $280)
  • Against the spread (ATS): Lions -6.5 (-110) | Bears +6.5 (-110)
  • Over/Under (O/U): 48 (O: -110 | U: -110)

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Lions at Bears key injuries

Lions

  • Brian Branch (calf) questionable
  • RB David Montgomery (knee) out

Bears

  • Ryan Bates (concussion) out
  • Teven Jenkins (calf) questionable
  • CB Jaylon Johnson (illness) questionable

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Lions at Bears picks and predictions

Prediction

Lions 34, Bears 17

Moneyline

The price on Lions ML (-350) has gone up 50 cents since Monday in our first look.

The narrative of Lions QB Jared Goff struggling on the road (and more specifically in outdoor stadiums) hasn’t affected the market’s confidence in Detroit to win straight up.

The Lions have become so heavily favored on the ML that bettors should look elsewhere for more optimal value.

PASS.

Against the spread

On the other hand, the lack of movement on the spread works well for Lions bettors. The Bears are a deeply flawed team, and while division games often bring out odd results in favor of underdogs, the Lions are simply better built on both sides of the ball.

Take advantage of the early optimism that the Bears shouldn’t be getting more than 6.5 points, and bet the other side.

All things equal, I would recommend waiting to see if any action moves in Chicago’s direction, then pounce on any Detroit discount. However, if you must act, the TD-with-a-hook points are worth giving to the favorites.

BET LIONS -6.5 (-110).

Over/Under

Bears QB Caleb Williams doesn’t have to do much to carry Chicago’s likely end of this point total. Though Detroit’s injury-riddled defense looks ripe for the picking, Chicago’s own defense will struggle to keep up with the Lions’ high-octane offense.

With the weather not looking like an issue as of publish time, I would even look to squeeze more value out of this with an alternate line on FanDuel Sportsbook: Over 50.5 (+120).

BET OVER 48 (-110) at BetMGM or BET OVER 50.5 (+120) at FanDuel.

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Buffalo Bills at Detroit Lions odds, picks and predictions

Analyzing Sunday’s Buffalo Bills at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The Buffalo Bills (10-3) take on the Detroit Lions (12-1) Sunday in Week 15. Kickoff from Ford Field is set for 4:25 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Bills vs. Lions odds, and make our expert NFL picks and predictions.

The Bills were marched out of town by the LA Rams in a 44-42 defeat in Week 14. They made a late push, down 38-21 in the fourth quarter, but it wasn’t enough. QB Josh Allen had a huge game, going 22-for-37 for 342 yards, 3 TDs and 0 INTs while rushing 10 times for 82 yards and 3 more TDs.

The Lions won their 11th straight in a 34-31 win over the Green Bay Packers Dec. 5. QB Jared Goff was 32-for-41 for 283 yards, 3 TDs and 1 INT. He spread the ball around to 6 different receivers that had 5 grabs apiece. WR Tim Patrick introduced himself with a 6-43-2 evening.

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Bills at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 5:42 p.m. ET.

  • Moneyline (ML): Bills +120 (bet $100 to win $120) | Lions -145 (bet $145 to win $100)
  • Against the spread (ATS): Bills +2.5 (-110) | Lions -2.5 (-110)
  • Over/Under (O/U): 54.5 (O: -110 | U: -110)

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Bills at Lions key injuries

Bills

  • CB Rasul Douglas (knee) out
  • S Damar Hamlin (back, ribs) questionable
  • TE Dalton Kincaid (knee) questionable
  • S Taylor Rapp (neck, shoulder) questionable

Lions

  • LB Trevor Nowaske (concussion) out

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Bills at Lions picks and predictions

Prediction

Bills 24, Lions 20

Moneyline

I’m taking Buffalo here. They’re getting Kincaid back, despite his questionable tag, and WR Keon Coleman (wrist) returns as well. Allen is playing on another level right now as he seeks his first MVP award. The Lions have been off for 10 days and don’t really need to be as hungry at 12-1.

Take the BILLS +120.

Against the spread

I’d consider the Bills’ side of the spread if it swells to 3.5 by kickoff. There’s no point in taking it here, though. Instead, give me JOSH ALLEN ANYTIME TOUCHDOWN (+115). He has one in 4 straight games and 6 during that span.

Over/Under

I like the Under here in a defensive struggle. The Lions are 2-3-1 O/U in their last 6. Buffalo is 4-0-1 in its last 5, but that’s thanks to scoring 30+ points in 7 straight games. That’s not happening here.

Take the UNDER 54.5 (-110).

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Green Bay Packers at Detroit Lions odds, picks and predictions

Analyzing Thursday’s Green Bay Packers at Detroit Lions odds and lines, with expert NFL picks and predictions.

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A NFC North rivalry hits Thursday Night Football as the Detroit Lions (11-1) host the Green Bay Packers (9-3). Kickoff is scheduled at 8:15 p.m. ET (Prime Video) from Ford Field in Motown. Let’s analyze BetMGM Sportsbook’s NFL odds around the Packers vs. Lions odds, and make our expert NFL picks and predictions.

Two storied franchises in arguably the NFL’s most competitive division showcase their second matchup of the season. The Lions prevailed 24-14 in the first contest during rainy, wet conditions at Lambeau Field in Week 9, on the back of touchdowns by WR Amon-Ra St. Brown and RB Jahmyr Gibbs.

Since its only loss of the season, Week 2 to the Tampa Bay Buccaneers 20-16, Detroit has rattled off 10 straight wins, a streak punctuated by its 23-20 escape in which the Chicago Bears botched a chance to tie or win in Lions territory in the final minutes.

The Packers rolled over the Miami Dolphins 30-17 at chilly Lambeau Field on Thanksgiving night to notch their seventh win in eight games.

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Packers at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Wednesday at 12:26 p.m. ET.

  • Moneyline (ML): Packers +155 (bet $100 to win $155) | Lions -190 (bet $190 to win $100)
  • Against the spread (ATS): Packers +3.5 (-115) | Lions -3.5 (-105)
  • Over/Under (O/U): 51.5 (O: -110 | U: -110)

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Packers at Lions key injuries

Packers

  • CB Jaire Alexander (knee) questionable
  • WR Romeo Doubs (concussion) questionable
  • RB Josh Jacobs (calf) questionable

Lions

  • CB Carlton Davis III (knee) probable
  • DL DJ Reader (shoulder) questionable

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Packers at Lions picks and predictions

Prediction

Lions 27, Packers 23

Moneyline

The biggest difference will be whether Alexander can suit up for the Packers and help contain the passing game. The lockdown cornerback has not yet played a divisional opponent this season, and his presence could force Detroit to adjust.

However, the Lions rank 7th in EPA per rush (0.03), so they’re comfortable in adjusting by leaning on Gibbs and RB David Montgomery. Green Bay can, of course, hold its own with Jacobs, as long as he’s healthy.

Even with Green Bay’s offensive stock matching Detroit’s almost position-for-position, siding against the Lions on their home turf would be a mistake.

Detroit’s (-178) ML listed on FanDuel Sportsbook offers better value than BetMGM in this market.

BET LIONS (-178) at FanDuel Sportsbook.

Against the spread

Books and bettors have generally priced Detroit correctly this season; the Lions have compiled a 9-3 record ATS. Green Bay has split the difference at 6-6.

The Packers will naturally keep this close, but in a toss-up, take the lesser juice ATS.

BET LIONS -3.5 (-105).

Over/Under

These squads are an identical 5-6-1 on the O/U, which likely has transpired because of their excellent run games that can slow down the pace and, in turn, scoring totals.

Many will point to the full week of rest for these teams after each played on Thanksgiving to favor a higher-octane offensive performance, and the above prediction credits plenty of touchdowns. This game will also take place indoors instead of in weather elements, which impacted their first meeting this year.

However, especially if Alexander plays, these 2 teams likely will try to eat as much clock as possible on the ground.

BET UNDER 51.5 (-110).

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Chicago Bears at Detroit Lions odds, picks and predictions

Analyzing Thursday’s Chicago Bears at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The Chicago Bears (4-7) and Detroit Lions (10-1) meet on Thanksgiving Day. Kickoff Thursday from Ford Field is set for 12:30 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Bears vs. Lions odds, and make our expert NFL picks and predictions.

Chicago lost 30-27 in overtime to the Minnesota Vikings on Sunday as a 3-point underdog. Chicago allowed a whopping 452 yards to Minnesota in losing its fifth straight game.

Detroit is on a 9-game winning streak after beating the Indianapolis Colts 24-6 Sunday while covering as a 7-point favorite. After going scoreless in the first quarter, the Lions scored twice in the second quarter to take command. The Lions gained 390 yards while holding the Colts to just 268 yards and a pair of field goals.

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Bears at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Wednesday at 1:07 a.m. ET.

  • Moneyline (ML): Bears +400 (bet $100 to win $400) | Lions -550 (bet $550 to win $100)
  • Against the spread (ATS): Bears +10 (-105) | Lions -10 (-115)
  • Over/Under (O/U): 48.5 (O: -110 | U: -110)

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Bears at Lions key injuries

Bears

  • WR Keenan Allen (ankle) questionable
  • RB D’Andre Swift (groin) questionable

Lions

  • None

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Bears at Lions picks and predictions

Prediction

Lions 28, Bears 17

Moneyline

PASS.

The Lions (-550) should pick up the win here against their NFC North  opponent, but such a heavy favorite is never worth the risk of betting on. Bet on the spread and/or total instead.

Against the spread

BET LIONS -10 (-115).

Detroit has covered the spread in 2 straight games and is 8-2 ATS in its last 10 games. It has 6 double-digit wins in the last 8 games.  On the other hand, the Bears are only 1-3-1 ATS in their last 5 games. The Lions have also covered ATS in 3 of their last 5 games against the Bears.

Over/Under

LEAN UNDER 48.5 (-110).

The Under has hit in 4 of Chicago’s last 6 games and is 7-4 for the Bears this season. The Under has also hit in 2 of the last 3 Chicago-Detroit matchups.

Detroit’s defense has been locked in of late, allowing just 12 points in its last 2 games combined.

This is a lean because the Lions have a very explosive offense that make betting the Under for any game a risk.

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Detroit Lions at Indianapolis Colts odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Indianapolis Colts odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (9-1) travel to face the Indianapolis Colts (5-6) Sunday in Week 12. Kickoff from Lucas Oil Stadium is scheduled for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Lions vs. Colts odds, and make our expert NFL picks and predictions.

The offensive power on hand in this one alone makes this worth watching. The NFC-leading Lions, of course, have plenty of pass-catchers to help QB Jared Goff, and Indianapolis becomes more interesting with QB Anthony Richardson returning to his starting gig.

Detroit has rattled off 8 straight wins following a Week 2 loss to the Tampa Bay Buccaneers and, most recently, obliterated the Jacksonville Jaguars 52-6.

Richardson’s presence under center (272 passing yards, 1 pass TD, 2 rushing TDs) helped push Indy to a 28-27 win over the New York Jets in Week 12 and halt a 3-game losing streak.

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Lions at Colts odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 2:40 p.m. ET.

  • Moneyline (ML): Lions -400 (bet $400 to win $100) | Colts +310 (bet $100 to win $310)
  • Against the spread (ATS): Lions -7.5 (-105) | Colts +7.5 (-115)
  • Over/Under (O/U): 50.5 (O: -110 | U: -110)

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Lions at Colts key injuries

Lions

  • CB Terrion Arnold (groin) questionable

Colts

  • None

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Lions at Colts picks and predictions

Prediction

Lions 30, Colts 23

Moneyline

Bettors backing Detroit will not get value in a matchup like this. Find other ways to make bank off the Lions for this one.

PASS.

Against the spread

The Colts are among several teams tied for first at 4-1 ATS at home. Anyone looking to fade the Lions should prefer to take the points instead of banking on an outright win.

Richardson should do plenty through the air against Detroit, which gives up the sixth-most passing yards per game (232.7).

Perhaps I would try to wait for the juice to move in a better direction, but it probably isn’t worth it if you’re sacrificing this favorable number on Indianapolis’ side.

BET COLTS +7.5 (-115).

Over/Under

The total is justifiably high but carries the best bet for this matchup. Hammer those points!

Richardson taking over for QB Joe Flacco increases the Colts’ weekly scoring ceiling, and the Lions probably boast the best offense in the NFL.

These 2 teams playing indoors on turf should provide plenty of sparks.

BET OVER 50.5 (-110).

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Detroit Lions at Green Bay Packers odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Green Bay Packers odds and lines, with expert NFL picks and predictions.

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The Green Bay Packers (6-2) welcome the Detroit Lions (6-1) to Lambeau Field Sunday. Kickoff is set for 4:25 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Lions vs. Packers odds, and make our expert NFL picks and predictions.

The Lions beat the Tennessee Titans 52-14 at home in Week 8 action, covering as a 13-point favorite. Detroit sits atop the NFC North and has won 5 straight games and has covered in each as well. The Lions are 6-1 against the spread (ATS). They have been on fire offensively, scoring at least 31 points in 4 straight games and 42-plus points 3 of those 4.

The Packers are coming into this battle just as hot, having won 4 in a row. They beat the Jacksonville Jaguars on the road Sunday 30-27, closing as a 3.5-point favorite. Green Bay is 2-2 ATS at home and 4-4 ATS on the season. It also has a dynamic attack, having scored at least 24 points in all but 1 game. QB Jordan Love has thrown for 15 TDs in 6 games.

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Lions at Packers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 1:05 a.m. ET.

  • Moneyline (ML): Lions -140 (bet $140 to win $100) | Packers +120 (bet $100 to win $120)
  • Against the spread (ATS): Lions -2.5 (-115) | Packers +2.5 (-105)
  • Over/Under (O/U): 47.5 (O: -110 | U: -110)

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Lions at Packers key injuries

Lions

  • DT Brodric Martin (knee) out
  • DE Joshua Paschal (illness) out
  • LB Malcolm Rodriguez (ankle) out

Packers

  • CB Jaire Alexander (knee) questionable
  • RB Josh Jacobs (ankle) questionable
  • QB Jordan Love (groin) questionable
  • G Josh Myers (wrist) doubtful
  • S Evan Williams (hamstring) out

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Lions at Packers picks and predictions

Prediction

Lions 31, Packers 27

Moneyline

PASS.

The moneyline has value for both sides, but the preferred side to play the favorite is on the spread as the wager has more bang for your buck. In this case, pass on a moneyline play.

Against the spread

BET LIONS -2.5 (-115).

The Packers are just too banged up to take here. They have their starting RB, CB and QB listed as questionable. The Packers are also just 2-3 ATS in their last 5 games. Love has also been far too turnover-prone, having thrown 9 INTs in 6 starts.

The Lions have covered in 5 straight games, 3 on the road. They are 3-0 ATS as a favorite of 5 or fewer points. QB Jared Goff has a 74.1% completion rate and just 4 turnovers. He’s a more trustworthy option, and the Lions are the less injured side.

Back LIONS -2.5 (-115).

Over/Under

BET OVER 48.5 (-110).

The Lions have been on fire offensively and have scored 47 or more points in 2 of their last 3 games. They have gone Over in 4 straight and are 4-3 O/U on the season. They are 2-1 O/U on the road.

The Packers are 4-3-1 O/U on the season and have scored 30 or more points in 2 of their last 3 games. They have allowed at least 22 popints in 2 straight as well, so their defense has struggled more often than it did earlier in the season.

With that in mind, back OVER 48.5 (-110).

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Tennessee Titans at Detroit Lions odds, picks and predictions

Analyzing Sunday’s Tennessee Titans at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The Tennessee Titans (1-5) visit the Detroit Lions (5-1) Sunday afternoon. Kickoff from Ford Field is scheduled for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Titans vs. Lions odds, and make our expert NFL picks and predictions.

The Titans have lost back-to-back games after falling 34-10 against Buffalo last week and failing to cover as 10-point road underdogs. QB Mason Rudolph went 25-of-40 for 215 yards with a touchdown and an interception.

The Lions have won 4 games in a row after handing the Vikings their first loss of the season with a final result of 31-29 and covering as 1-point road underdogs. QB Jared Goff went 22-of-25 for 280 yards with 2 TDs while RB Jahmyr Gibbs carried the ball 15 times for 116 yards and 2 TDs.

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Titans at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 3 p.m. ET.

  • Moneyline (ML): Titans +475 (bet $100 to win $475) | Lions -650 (bet $650 to win $100)
  • Against the spread (ATS): Titans +11.5 (-110) | Lions -11.5 (-110)
  • Over/Under (O/U): 45 (O: -110 | U: -110)

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Titans at Lions key injuries

Titans

  • LB Jerome Baker (rest) questionable
  • LB Cedric Gray (shoulder) out
  • QB Will Levis (shoulder) questionable
  • CB L’Jarius Sneed (quadricep) out
  • RB Tyjae Spears (hamstring) questionable

Lions

  • Christian Mahogany (illness) out
  • DE Joshua Paschal (illness) out

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Titans at Lions picks and predictions

Prediction

Lions 31, Titans 17

Moneyline

PASS.

There is no value on the Lions (-650) to win on Sunday.

Against the spread

BET LIONS -11.5 (-110).

The Titans fell 34-10 last week against the Bills with their offense struggling to move the ball and their defense struggling to get stops. The Lions are fresh off a critical road win after knocking off the undefeated Vikings. Detroit has won 2 of its last 3 games by 13 or more points while scoring 42 or more points in each game.

Over/Under

BET OVER 45 (-110).

The Lions have hit the Over in each of their last 3 weeks while scoring 31 or more points in each game. They have also allowed 29 points in 2 of their last 3 weeks. The Titans have avoided the Under in 4 of their last 5 games while allowing 24 or more points in 4 of their last 6 games.

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Detroit Lions at Minnesota Vikings odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Minnesota Vikings odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (4-1) visit the Minnesota Vikings (5-0) Sunday in a key NFC North battle. Kickoff from U.S. Bank Stadium is set for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Lions vs. Vikings odds, and make our expert NFL picks and predictions.

Detroit blew out the Dallas Cowboys 47-9 Sunday while covering as a 3.5-point favorite. QB Jared Goff went 18-for-25 for 315 yards and 3 TDs and has thrown for 607 yards and 5 TDs without an INT in his last 2 games. The Lions have scored 40+ points in each of their last 2 games.

Minnesota, who was off last week, escaped with a 23-17 win over the New York Jets in its last outing on Oct. 6, covering a as a 2.5-point favorite. Minnesota’s offense did not play well in the win, totaling 253 total yards and scoring just 1 TD, but the Vikings’ defense forced 3 turnovers. Among those turnovers was a 63-yard Pick 6 by LB Andrew Van Ginkel.

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Lions at Vikings odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 8:49 p.m. ET.

  • Moneyline (ML): Lions +105 (bet $100 to win $105) | Vikings -125 (bet $125 to win $100)
  • Against the spread (ATS): Lions +1.5 (-110) | Vikings -1.5 (-110)
  • Over/Under (O/U): 50.5 (O: -110 | U: -110)

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Lions at Vikings key injuries

Lions

  • CB Carlton Davis (quad) questionable
  • Kevin Zeitler (groin) questionable

Vikings

  • LB Blake Cashman (toe) doubtful
  • CB Akayleb Evans (hip) questionable
  • TE T.J. Hockenson (knee) out
  • RB Aaron Jones (hamstring) questionable
  • DT Harrison Phillips (shoulder) questionable

FOOTBALL NEVER STOPS
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Lions at Vikings picks and predictions

Prediction

Lions 24, Vikings 21

Moneyline

BET LIONS (+105).

Minnesota’s offense did not play well in its last outing, and Detroit has looked like arguably the best team in the NFL over the last 2 weeks. I also am not yet sold on the Vikings and the resurgence of QB Sam Darnold, so look for the Lions to end Minnesota’s undefeated season.

I am not a huge fan of doubling down on a team’s ML and run line for the same game, but the odds here are too good for me to recommend passing up. If you prefer playing the spread, play it, but you can divvy up units between both bets.

Against the spread

BET LIONS +1.5 (-110).

Detroit is the better team to me, and the Lions have played better lately than the Vikings. I know the Vikings are hot, but I expect Detroit to ride the momentum from that blowout vs. Dallas into a win here. I trust Detroit’s offense more than any facet of Minnesota’s game, so that alone will help the Lions cover here.

Over/Under

LEAN UNDER 50.5 (-110). 

The Under has hit in 4 of Minnesota’s 5 games this season and is 3-2 for the Lions this year. Minnesota has a very good defense that allows just 15.2 points per game, and with this being a divisional game, I expect this to be more of a grind it out game.

This is a lean because Detroit’s offense has been phenomenal in its last 2 games, so there is always a risk when betting on the Under when such a good offense is playing.

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Detroit Lions at Dallas Cowboys odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Dallas Cowboys odds and lines, with expert NFL picks and predictions.

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The Dallas Cowboys (3-2) welcome the Detroit Lions (3-1) to AT&T Stadium Sunday for a clash of Super Bowl-caliber sides. Kickoff is set for 4:25 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Lions vs. Cowboys odds, and make our expert NFL picks and predictions.

The Cowboys beat the Pittsburgh Steelers 20-17 on Sunday night in Week 5, closing as a 2.5-point underdog. They have won 2 straight and are 2-1 against the spread (ATS) as an underdog. Dallas is led by QB Dak Prescott and has been consistent offensively, averaging 23.4 points per game (PPG). Defensively, it has allowed 17 points or less in 3 of its 5 games, but ranks 23rd with an average of 24.2 PPG allowed.

The Lions had a Week 5 bye. They are coming off a 42-29 win in Week 4 over the Seattle Seahawks. Detroit has won 2 straight, has been favored in every game and is 3-1 ATS. The Lions’ defense has been routinely among their strengths, and they rank 10th at 20.1 PPG allowed. Detriot, which is led by QB Jared Goff, ranks 7th in the league averaging 26.0 PPG.

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Lions at Cowboys odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated at 12:21 a.m. ET.

  • Moneyline (ML): Lions -165 (bet $165 to win $100) | Cowboys +140 (bet $100 to win $140)
  • Against the spread (ATS): Lions -3 (-115) | Cowboys +3 (-105)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

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Lions at Cowboys key injuries

Lions

  • OL Christian Mahogany (illness) out

Cowboys

  • CB DaRon Bland (foot) questionable
  • DB Caelen Carson (shoulder) questionable
  • LB Eric Kendricks (calf/shoulder) out
  • LB Nick Vigil (foot) questionable
  • LB Micah Parsons (ankle) out

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Lions at Cowboys picks and predictions

Prediction

Lions 30, Cowboys 24

Moneyline

PASS.

The Cowboys are America’s team and should be a popular pick on both the moneyline and spread as a home underdog. However, the Lions should be the only play here. But they are too expensive to play on the moneyline.

Against the spread

BET LIONS -3 (-115).

The Cowboys’ defensive strength is in the passing game, ranking 11th at 271 yards allowed per game. They also rank in the top 12 in opponents’ completion percentage, but the Lions don’t pass the ball much, sitting within the bottom 7 in pass percentage.

Detroit, with Parsons sidelined, should abuse the Cowboys on the ground. Dallas is 0-2 at home and 0-2 ATS at home. The Lions are 3-1 ATS this season and 1-0 ATS on the road. They are 3-0 ATS as a favorite of a touchdown or less.

Take LIONS -3 (-115).

Over/Under

BET OVER 52.5 (-110).

The Cowboys are going to need to score frequently to keep pace in this game. They have scored 20 points or more in 4 of 5 games and have gone Over in 3 of 5 games. Dallas has played well defensively, but will be short its best defensive player in this battle.

The Lions went Under in their 1st 3 games of the season, but scored 20 points in 2 of those 3. They scored 42 points on the Seahawks before their bye and are both healthy and rested coming into this game. Detroit has scored 31 PPG in its last 2.

There should be ample scoring in this one. Take OVER 52.5 (-110).

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Seattle Seahawks at Detroit Lions odds, picks and predictions

Analyzing Monday’s Seattle Seahawks at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The Seattle Seahawks (3-0) and Detroit Lions (2-1) meet Monday with Kickoff from Ford Field is scheduled for 8:15 p.m. ET (ABC/ESPN+). Let’s analyze BetMGM Sportsbook’s NFL odds around the Seahawks vs. Lions odds, and make our expert NFL picks and predictions..

The Seahawks stayed unbeaten with a 24-3 win over the Miami Dolphins in Week 3, covering the 4-point spread as the Under (42) hit. RB Zach Charbonnet stepped up with 91 rushing yards and 2 TDs, while WR DK Metcalf recorded his 2nd straight 100-yard game and had a TD.

The Lions secured a 20-13 road win in Week 3 against the Arizona Cardinals, covering as 3-point favorites and hitting the Under 51 total. RBs David Montgomery and Jahmyr Gibbs combined for 188 rushing yards and a TD, while WR Amon-Ra St. Brown had 75 receiving yards and caught his 1st TD of the season.

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Seahawks at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Sunday at 3:46 p.m. ET.

  • Moneyline (ML): Seahawks +165 (bet $100 to win $165) | Lions -200 (bet $200 to win $100)
  • Against the spread (ATS): Seahawks +4 (-110) | Lions -4 (-110)
  • Over/Under (O/U): 46.5 (O: -110 | U: -110)

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Seahawks at Lions key injuries

Seahawks

  • DT Byron Murphy II (hamstring) out
  • DE Leonard Williams (ribs) out
  • LB Boye Mafe (knee) out
  • LB Uchenna Nwosu (knee) out
  • LB Jerome Baker (hamstring) questionable

Lions

  • C Frank Ragnow (pectoral) out
  • CB Ennis Rakestraw Jr. (hamstring) questionable

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Seahawks at Lions picks and predictions

Prediction

Lions 24, Seahawks 21

Moneyline

PASS.

This will be a tight game that will likely come down to a late field goal to win it. It’ll come down to who gets the ball last which is why I’m going to avoid the moneyline and look to the spread.

Against the spread

BET SEAHAWKS +4 (-110).

Coach Mike Macdonald has Seattle playing like a complete team, ranking 2nd in total DVOA, with balanced top-10 rankings on offense and defense. Despite facing manageable opponents so far (the Denver Broncos, New England Patriots and Miami), they’ve looked more refined each week, and their undefeated start speaks volumes. Their passing game, led by dynamic receivers, poses a tough challenge for a Detroit secondary that has allowed a 67% completion rate to opposing QBs.

Detroit, on the other hand, hasn’t quite lived up to the early season hype. While they are still a formidable team, they’ve struggled with turnovers and finishing drives, and even top offensive coordinator Ben Johnson has yet to find his rhythm this season. Their inconsistent offense has kept games closer than expected, as seen in tight matchups with the LA Rams and Cardinals, and a loss to the Tampa Bay Buccaneers at home.

Seattle’s defense has shown resilience and promise, and their offense should be able to keep pace against a Lions squad that’s yet to put it all together. With Detroit’s issues and Seattle’s steady rise, taking the Seahawks to cover the spread makes sense in this matchup.

Over/Under

PASS.

There’s no strong edge here—recent trends are mixed. The Over has only hit in 5 of their last 9 meetings, while Seattle is 5-4-1 against the Over and Detroit is 5-5. Both teams combine for an average of 45 points per game, which is almost right on the line. With no clear trends or consistent offensive output pointing either way, it’s best to avoid this bet altogether.

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