The Colorado Buffaloes (1-8, 1-5 Pac-12) meet the No. 8 USC Trojans (8-1, 6-1) Friday at the Los Angeles Memorial Coliseum. Kickoff is scheduled for 9:30 p.m. ET (FS1). Below, we analyze Tipico Sportsbook‘s lines around the Colorado vs. USC odds, and make our expert college football picks and predictions.
The Buffaloes have dropped 3 straight games since their lone win over California on Oct. 15. Colorado has also covered just 2 of its 9 games overall, while going 0-4 SU and ATS on the road in 4 tries.
The Trojans have won 2 straight games, 41-15 against Cal last week and 45-37 over Arizona the week before. USC has scored 41 or more points in 3 in a row, and 7 of 9 games overall, cashing the Over at a 6-3 clip this season.
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Colorado at USC odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 7:36 a.m. ET.
- Moneyline (ML): Colorado +1500 (bet $100 to win $1,500) | USC -10000 (bet $10,000 to win $100)
- Against the spread: Colorado +33.5 (-108) | USC -33.5 (-112)
- Over/Under (O/U): 66.5 (O: -108 | U: -112)
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Colorado at USC picks and predictions
Prediction
USC 51, Colorado 20
Moneyline
USC (-10000) will cost you $100 for every $1 won. That’s a non-sensical bet, and would never be OK under any circumstances.
PASS.
Against the spread
Hold your nose and play COLORADO +33.5 (-108).
The Buffaloes have been horrendous this season, but even they should be able to move the ball at least a little bit against USC -33.5 (-112). The Trojans have rolled up 41.0 PPG, ranking 7th overall, but this is also a defense which has yielded 25.2 PPG, and it allowed Cal to hang 35 on them last week at the Coliseum. There are plenty of red flags with the USC defense, so Colorado should be able to keep it within 5 TDs.
Over/Under
OVER 66.5 (-108) is lean here, ever so slightly.
The Over has hit in 6 of the last 8 games overall for Colorado, while going 4-0 in the last 4 road games. The Over is also 9-2 in USC’s last 11 home games, while cashing in 4 of the last 5 inside the conference.
The Trojans will roll up plenty of points with the Buffs allowed 40.2 PPG, so the Buffs’ offense won’t have to do much to get an Over winner here. Even if CU is in the teens you should be OK.
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