First look: Colorado at Arizona odds and lines

Looking at Saturday’s Colorado at Arizona college football odds, lines and trends. Here’s what you need to know.

The Colorado Buffaloes (0-4, 0-1 Pac-12) take on the Arizona Wildcats (2-2, 0-1) in the second week of Pac-12 play Saturday. Kickoff from Arizona Stadium is at 9:30 p.m. ET (Pac-12 Network). Below, we look at Colorado vs. Arizona school odds from Tipico Sportsbook; check back for all our college football picks and predictions.

Colorado has lost its first 4 games of the season. The Buffaloes scored a season-high 17 points in a 45-17 loss to UCLA Saturday. They have lost every game by at least 25 points.

Arizona lost its Pac-12 opener with a 49-31 loss to California Saturday. The Wildcats have averaged 29.3 points per game so far this season. Junior transfer QB Jayden De Laura has 1,149 passing yards, 8 touchdowns and 6 interceptions.

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Colorado at Arizona odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at  3 p.m. ET.

  • Money line (ML): Colorado +570 (bet $100 to win $570) | Arizona -850 (bet $850 to win $100)
  • Against the spread (ATS): Colorado +17.5 (-110) | Arizona -17.5 (-110)
  • Over/Under (O/U): 55.5 (O: -112 | U: -108)

2022 betting stats

  • ML: Colorado 0-4 | Arizona 2-2
  • ATS: Colorado 0-4 | Arizona 2-2
  • O/U: Colorado 3-1 | Arizona 3-1

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Colorado vs. Arizona head-to-head

These teams have faced each other only 24 times but it will be the 12th year in a row since Colorado joined the conference and has been in the same division as Arizona.

The Buffaloes have a 16-8 advantage all-time and won the last 2 seasons when the two teams played, including a 24-13 win in 2020 the last time they met in Tuscon.

However, since Colorado joined the Pac-12, Arizona has won 7 of the 11 games.

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