Colorado at Arizona odds, picks and predictions

Analyzing Saturday’s Colorado Buffaloes at Arizona Wildcats odds and lines, with college football expert picks, predictions and best bets.

The Colorado Buffaloes (0-4, 0-1) and the Arizona Wildcats (2-2, 0-1) meet Saturday at Arizona Stadium in Tucson, Ariz. Kickoff is scheduled for 9:30 p.m. ET (PAC-12 Network). Below, we analyze Tipico Sportsbook‘s lines around the Colorado vs. Arizona odds, and make our expert college football picks and predictions.

The Buffaloes are off to a horrendous start, dropping all 4 games to date. To make matters worse, the Buffs have lost by 25 or more points, including last week’s 45-17 setback to UCLA in the Pac-12 opener. Colorado is 0-4 ATS, and it has cashed the Over in 3 in a row.

The Wildcats were outlasted in a crazy 49-31 game at California last week in the conference opener, and Arizona has alternated wins and losses, as well as covers and non-covers, through the first 4 outings. The Over is 3-1 to date.

Check out: AFCA Coaches Poll powered by USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Colorado at Arizona odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:10 a.m. ET.

  • Money line (ML): Colorado +600 (bet $100 to win $600) | Arizona -900 (bet $900 to win $100)
  • Against the spread (ATS): Colorado +17.5 (-115) | Arizona -17.5 (-107)
  • Over/Under (O/U): 57.5 (O: -110 | U: -110)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Colorado at Arizona picks and predictions

Prediction

Arizona 41, Colorado 17

Money line

Arizona (-900) should be able to get it done rather easily in this one, squaring its record inside the conference at 1-1. However, you can’t risk 9 times your potential return no matter how awful this Colorado (+600) team might be.

PASS.

Against the spread

ARIZONA -17.5 (-107) is the play there, and you can feel confident in laying the points since Colorado +17.5 (-115) has been blasted by 25 or more points in every game this season.

The Wildcats have struggled defensively this season, but Arizona’s pass attack is on point, posting 301.3 yards per game through the air to rank 22nd in the nation. It’s going to be another long night for Ralphie and the Buffs.

Over/Under

The OVER 57.5 (-110) is the LEAN, ever so slightly, but play this one lightly, or not at all.

The Over is 4-1 in the past 5 road games for Colorado, while going 5-1-1 in Arizona’s past 7 games overall, and 3-0-1 in the past 4 inside the Pac-12. The Over is also an impressive 8-3 in the previous 11 meetings in this series, although that’s due to some much better Colorado teams being able to move the ball. This offense is awful, but the good news is that both defenses are very giving.

Play our free daily Pick’em Challenge and win! Play now!

Want action on this game or any other NCAA football matchup? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Kevin J. Erickson on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1622]

First look: Colorado at Arizona odds and lines

Looking at Saturday’s Colorado at Arizona college football odds, lines and trends. Here’s what you need to know.

The Colorado Buffaloes (0-4, 0-1 Pac-12) take on the Arizona Wildcats (2-2, 0-1) in the second week of Pac-12 play Saturday. Kickoff from Arizona Stadium is at 9:30 p.m. ET (Pac-12 Network). Below, we look at Colorado vs. Arizona school odds from Tipico Sportsbook; check back for all our college football picks and predictions.

Colorado has lost its first 4 games of the season. The Buffaloes scored a season-high 17 points in a 45-17 loss to UCLA Saturday. They have lost every game by at least 25 points.

Arizona lost its Pac-12 opener with a 49-31 loss to California Saturday. The Wildcats have averaged 29.3 points per game so far this season. Junior transfer QB Jayden De Laura has 1,149 passing yards, 8 touchdowns and 6 interceptions.

Check out: AFCA Coaches Poll powered by USA TODAY sports

Stream select live college football games and full replays: Get ESPN+

Colorado at Arizona odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at  3 p.m. ET.

  • Money line (ML): Colorado +570 (bet $100 to win $570) | Arizona -850 (bet $850 to win $100)
  • Against the spread (ATS): Colorado +17.5 (-110) | Arizona -17.5 (-110)
  • Over/Under (O/U): 55.5 (O: -112 | U: -108)

2022 betting stats

  • ML: Colorado 0-4 | Arizona 2-2
  • ATS: Colorado 0-4 | Arizona 2-2
  • O/U: Colorado 3-1 | Arizona 3-1

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Colorado vs. Arizona head-to-head

These teams have faced each other only 24 times but it will be the 12th year in a row since Colorado joined the conference and has been in the same division as Arizona.

The Buffaloes have a 16-8 advantage all-time and won the last 2 seasons when the two teams played, including a 24-13 win in 2020 the last time they met in Tuscon.

However, since Colorado joined the Pac-12, Arizona has won 7 of the 11 games.

Play our free daily Pick’em Challenge and win! Play now!

Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1622]

[mm-video type=playlist id=01fb7dafw2b08817yr player_id=none image=https://sportsbookwire.usatoday.com/wp-content/plugins/mm-video/images/playlist-icon.png]