The Clemson Tigers (3-0, 1-0 ACC) and the Wake Forest Demon Deacons (3-0,0-0) meet Saturday at Truist Field in Winston-Salem, N.C. Kickoff is scheduled for noon ET (ABC). Below, we analyze Tipico Sportsbook‘s lines around the Clemson vs. Wake Forest school odds, and make our expert college football picks and predictions.
The Tigers enter Saturday undefeated but have failed to cover large spreads in their last 2 outings. Clemson has allowed just 42 points across its 3 games, as the Under is 2-1 to start the year.
Wake Forest also comes in undefeated and faces a stiff test as it opens ACC play. The Demon Deacons have been one of the more prolific teams in the national on the offensive side of the ball, scoring 42 points per game to rank 21st.
Clemson is No. 5 and Wake Forest is No. 16 in the AFCA Coaches Poll powered by USA TODAY Sports.
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Clemson at Wake Forest odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6 a.m. ET.
- Money line (ML): Clemson -300 (bet $300 to win $100) | Wake Forest +250 (bet $100 to win $250)
- Against the spread (ATS): Clemson -7.5 (-108) | Wake Forest +7.5 (-112)
- Over/Under (O/U): 55.5 (O: -110 | U: -110)
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Clemson at Wake Forest picks and predictions
Prediction
Clemson 27, Wake Forest 20
Money line
Clemson (-300) will cost you three times your potential return, and that’s risky business in a difficult road game at Wake Forest.
While Clemson has won each of its first 3 games by 23 or more points, this will easily be the most difficult opponent it has faced. The Tigers will have a chip on their shoulder after losing the Atlantic Division to the Deacs last season.
This is going to be a close game, and it’s not worth the risk for such a small return.
PASS.
Against the spread
WAKE FOREST +7.5 (-112) is the play here, especially because of the hook.
While Clemson is 4-0 ATS in its last 4 ACC games, including the Labor Day opener against Georgia Tech on a neutral field, the Tigers have just had a tough time with the Deacons for whatever reason.
Wake Forest is 7-3-1 ATS in the previous 11 meetings against Clemson in the Triad, and the Tigers are just 1-9 ATS in the past 10 appearances in September.
Over/Under
The UNDER 55.5 (-110) is worth a look here.
The Under is 5-1 in Clemson’s past 6 road games and is 22-7 in the past 29 games in September.
The Under has cashed in 7 of the last 10 home games for Wake Forest and is 9-3 in its last 12 games in September.
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