Clemson at South Carolina odds, picks and prediction

Analyzing Saturday’s Clemson at South Carolina odds and lines, with college football expert picks, predictions and best bets.

The Clemson Tigers (8-3, 6-2 ACC) head to Columba, S.C., to take on the South Carolina Gamecocks (6-5, 3-5 SEC) Saturday. Kickoff for the 118th edition of this rivalry game is 7:30 p.m. ET. Below, we look at the Clemson at South Carolina odds and lines, and make our expert college football picks, predictions and bets.

Clemson has recovered from a disastrous start to its season—the Tigers were 4-3, 0-7 ATS through their first seven games—to reel off four straight wins, three of which have covered the spread. The offense has picked things up, averaging 38.0 points per game over the last four contests, while the defense (319.7 yards per game; 15th nationally) has been excellent all year.

Rankings according to the AFCA Coaches Poll powered by USA TODAY Sports.

South Carolina is also finishing strong under first-year head coach Shane Beamer. The Gamecocks are coming off a 21-17 win vs. Auburn and also beat Florida 40-17 Nov. 6. The offense has been hampered by injuries at quarterback as it’s averaging just 332.2 yards per game (111th nationally) and 26.5 points per game (104th).

Clemson at South Carolina odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 7:45 a.m. ET.

  • Money line: Clemson -500 (bet $500 to win $100) | South Carolina +330 (bet $100 to win $330)
  • Against the spread (ATS): Clemson -10.5 (-115) | South Carolina +10.5 (-107)
  • Over/Under (O/U): 43.5 (O: -108 | U: -112)

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Clemson at South Carolina odds, lines, picks and predictions

Prediction

Clemson 30, South Carolina 17

Money line

We can’t really make a case for South Carolina winning this game, and the payout is too low for Clemson, so PASS on the money line.

Against the spread

It’s hard to see how South Carolina is going to put up many points with a fourth-string quarterback going up against a defense that has allowed 16.8 points per game this year. Further, Clemson’s running game is starting to wake up and should make hay against South Carolina’s 93rd-ranked rushing defense (171.4 yards per game).

The Tigers are on a six-game winning streak over South Carolina, and only one of those games has been close. Look for CLEMSON -10.5 (-115) to roll.

Over/Under

This is a low number and the Over has hit in three of these teams’ last four games. Look for Clemson to do most of the heavy lifting with its improved offense, while the defense will allow just enough points to take this OVER 43.5 (-108).

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