Clemson at Pitt odds, picks and predictions

Analyzing Saturday’s Clemson at Pitt odds and lines, with college football expert picks, predictions and best bets.

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The 16th-ranked Clemson Tigers (7-2, 6-1 ACC) and Pitt Panthers (7-2, 3-2) meet Saturday. Kickoff from Acrisure Stadium is scheduled for noon ET (ESPN / ESPN+). Let’s analyze FanDuel Sportsbook’s college football odds around the Clemson vs. Pitt odds, and make our expert college football picks and predictions.

These teams have the same overall record, but they’ve taken different ways to get here.

Clemson opened the season getting dusted by Georgia, 34-3, on a neutral field Aug. 31. It has won 7 of 8 games since, with only a 33-21 loss to Louisville Nov. 2. The Tigers are just 2-3 against the spread (ATS) in the past 5 outings. The Under has cashed in 5 of the past 6 contests, too.

Pitt opened the season with 7 straight wins, but it has dropped back-to-back games at SMU and home to Virginia. Last week’s loss to the Hoos was especially surprising, dropping a 24-19 game as a 7.5-point favorite as the Under (57) cashed. The Under is 4-1 in the past 5 outings.

RankingsUS LBM Coaches Poll: Conducted by the American Football Coaches Association and USA TODAY Sports

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Clemson at Pitt odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 8:37 a.m. ET.

  • Moneyline (ML): Clemson -450 (bet $450 to win $100) | Pitt +340 (bet $100 to win $340)
  • Against the spread: Clemson -11.5 (-110) | Pitt +11.5 (-110)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

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Clemson at Pitt picks and predictions

Prediction

Clemson 26, Pitt 20

Moneyline

Clemson (-450) will cost you nearly 5 times your potential return, and you can’t risk that much for a standalone bet or as part of a multi-leg parlay. Including the Tigers sucks all of the value out of your parlay ticket.

AVOID.

Against the spread

PITT +11.5 (-110) has seen the offense dry up in the past 2 losses, averaging just 22.0 PPG, while the defense has coughed up 36.0 PPG. The Panthers need to get back to basics to avoid a third consecutive setback.

Clemson -11.5 (-110) is tough, but it has had issues of its own on defense, allowing 31 or more points in 2 of the past 3 outings. The Tigers are just 2-3 ATS in the past 5 games, and Clemson is 1-3 ATS in the past 4 outings as a double-digit favorite. Back the Panthers.

Over/Under

UNDER 52.5 (-110) might be the best play on the board.

The total has gone low in 2 in a row, and 5 of the past 6 games, for Clemson. And, for Pitt, the Under has cashed in 4 of the previous 5 outings.

These teams have met each other 4 times since Nov. 12, 2016, with the Under cashing in each of the 2 meetings in Pittsburgh.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:
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First look: Clemson at Pitt odds and lines

Looking at Saturday’s Clemson at Pitt college football odds, lines and trends. Here’s what you need to know.

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The 16th-ranked Clemson Tigers (7-2, 6-1 ACC) and the Pitt Panthers (7-2, 3-2) meet Saturday at Acrisure Stadium in Pittsburgh. Kickoff is scheduled for noon ET (ESPN). Below, we look at Clemson vs. Pitt odds from FanDuel Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Tigers picked up a 24-14 win at Lane Stadium in Blacksburg against Virginia Tech, covering as 5.5-point favorites as the Under (54.5) cashed. The offense has taken a step back in the past 2 games, averaging just 22.5 points per game (PPG), but the defense has allowed 14 or fewer points in 4 of the past 6 outings. The Under is 5-1 in that 6-game span.

The Panthers opened the season with 7 straight wins, but they’ve dropped 2 in a row. Pitt was tripped up 48-25 at SMU on Nov. 2, and it lost Saturday 24-19 at home to Virginia despite being favored as a 7.5-point favorite. The Under (57) cashed and the Under is 4-1 across the previous 5 contests. Pitt was No. 23 but fell out of the rankings when the new poll was released Sunday afternoon.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Clemson at Pitt odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Sunday at 2:52 p.m. ET.

  • Moneyline (ML): Clemson -320 (bet $320 to win $100) | Pitt +255 (bet $100 to win $255)
  • Against the spread (ATS): Clemson -9.5 (-110) | Pitt +9.5 (-110)
  • Over/Under (O/U): 55.5 (O: -105 | U: -115)

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2024 betting stats

  • ML: Clemson 7-2 | Pitt 7-2
  • ATS: Clemson 5-4 | Pitt 6-3
  • O/U: Clemson 3-6 | Pitt 4-5

Clemson vs. Pitt head-to-head

Pitt leads the all-time series 3-2, while the teams have split 2-2 since becoming conference rivals in the ACC in 2016. The only previous meeting in Pittsburgh was the most recent battle on Oct. 23, 2001, a 27-17 win by the Panthers.

The teams also met in the ACC Championship on Dec. 1, 2018, which saw Clemson win 42-10 at Bank of America Stadium in Charlotte.

Prior to becoming conference rivals, these teams met just once before on Dec. 30, 1977, in the Gator Bowl in Jacksonville, Fla. The Panthers came away with a 34-3 victory in that outing.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:
Alabama / Arkansas / Auburn / Clemson / Colorado / DukeFlorida / Florida StateGeorgia / Iowa / KentuckyLSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / UCLA / USC / WashingtonWisconsin / Recruiting / Transfer portal / College Football Playoffs / College Sports Wire / High School

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