Cincinnati Reds at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Cincinnati Reds at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Cincinnati Reds (81-77) and Cleveland Guardians (74-84) meet Wednesday to conclude a 2-game series. First pitch from Progressive Field is set for 6:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Reds lead 2-1

SS Elly De La Cruz’s 1st career 2-homer game helped propel the Reds to an 11-7 victory over the Guardians as +109 road underdogs on Tuesday. The Reds are 1 1/2 games behind the Chicago Cubs for the final Wild Card berth.

With the loss, Cleveland fell into 3rd place in the AL Central, 1/2 game behind the Detroit Tigers. The Minnesota Twins have already clinched the division title.

Reds at Guardians projected starters

LHP Andrew Abbott vs. RHP Shane Bieber

Abbott (8-5, 3.70 ERA) makes his 21st start. He has a 1.27 WHIP, 3.7 BB/9 and 10 K/9 in 107 innings.

  • Last outing: No-decision, 4 1/3 IP, 2 ER, 4 H, 2 BB, 7 K in a 7-5 home loss Friday vs. the Pittsburgh Pirates
  • Career vs. Cleveland: 1-0, 3.60 ERA (5 IP, 2 ER), 6 H, 0 BB, 5 K in 1 start

Bieber (5-6, 3.91 ERA) makes his 21st start. He has a 1.25 WHIP, 2.5 BB/9 and 7.4 K/9 in 122 innings.

  • Last outing: No-decision, 5 IP, 4 ER, 6 H, 1 BB, 5 K in a 9-8 home win Friday vs. the Baltimore Orioles
  • Career vs. Cincinnati: 3-0, 3.51 ERA (33 1/3 IP, 13 ER), 24 H, 9 BB, 39 K in 5 starts

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Reds at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 11:08  p.m. ET.

  • Moneyline (ML): Reds +110 (bet $100 to win $110) | Guardians -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds +1.5 (-200) | Guardians -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Reds at Guardians picks and predictions

Prediction

Reds 3, Guardians 1

Moneyline

BET REDS (+110).

The Reds are the better team and have much more to play for and they are also  the hotter team, having won 2 straight while the Guardians have lost 3 in a row. Cincinnati is also better on the road (43-34) than Cleveland is at home (41-39).

Run line/Against the spread

PASS.

I feel confident in picking the Reds to cover here but at +1.5 (-200) the line is far too risky. Bet on the moneyline and/or total instead.

Over/Under

LEAN UNDER 7.5 (-105).

The Under is 3-1 in the last 4 Cincinnati-Cleveland matchups overall and is 4-2 in Cleveland’s last 6 overall. The Under has also hit in 3 of Abbott’s last 5 starts and hit in his only career start vs. Cleveland.

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Cincinnati Reds at Cleveland Guardians odds, picks and predictions

Analyzing Tuesday’s Cincinnati Reds at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Cincinnati Reds (80-77) and the Cleveland Guardians (74-83) kick off a 2-game interleague series Tuesday at Progressive Field. First pitch is scheduled for 6:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Reds vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The Reds snapped a 4-game losing streak Sunday, grabbing a much-needed win in 3-game set in Pittsburgh against the already eliminated Pirates. Cincinnati currently sits 2 1/2 games out of the final NL Wild Card spot with 5 games remaining. Analytics shows the Reds with a mere 8.2% chance of making the postseason.

The Guardians gave the Baltimore Orioles a hard time over the weekend, splitting a 4-game set. Cleveland’s offense dried up in the final 2 games, both losses, totaling just 2 runs. The Under has cashed in 4 of the past 5 games for the Guardians.

Reds at Guardians projected starters

RHP Hunter Greene vs. RHP Lucas Giolito

Greene (4-6, 4.24 ERA) makes his 21st start. He has a 1.35 WHIP, 4.0 BB/9 and 12.4 K/9 in 104 innings.

  • Last start: No-decision, 7 IP, 1 ER, 3 H, 1 BB, 14 K in 5-3 home loss vs. the Minnesota Twins last Wednesday
  • 2023 road splits: 3-2, 3.68 ERA (63 2/3 IP, 26 ER), 4 HR, .227 OBA in 12 starts

Giolito (8-14, 4.60 ERA) makes his 32nd start. He has a 1.26 WHIP, 3.3 BB/9 and 10.0 K/9 in 176 innings with the White Sox, Angels and Guardians.

  • Last start: Loss, 5 1/3 IP, 4 R (3 ER), 7 H, 3 BB, 6 K in 6-2 road loss vs. the Kansas City Royals last Wednesday
  • 2023 home splits: 5-4, 3.19 ERA (84 2/3 IP, 30 ER), 12 HR, .193 OBA in 14 starts

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Reds at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:58 a.m. ET.

  • Moneyline (ML): Reds -110 (bet $110 to win $100) | Guardians -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Reds -1.5 (+155) | Guardians +1.5 (-190)
  • Over/Under (O/U):  8 (O: -105 | U: -115)

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Reds at Guardians picks and predictions

Prediction

Reds 4, Guardians 2

Moneyline

The REDS (-110) are a solid play on the road against the Guardians (-110).

While Cincinnati hasn’t exactly played with a sense of urgency, dropping 4 of the past 5 games overall at an inopportune time, and just 11-11 in the month of September, it should take care of business in Cleveland.

Giolito has been very giving, serving up 37 HR in 176 IP overall, including 7 dingers in just 22 IP across 4 starts since landing in Cleveland, losing 3 of those outings.

Run line/Against the spread

The REDS -1.5 (+155) are a solid play on the run line, as I expect Cincinnati to power up against Giolito, and cover in a much-needed win against the Guardians +1.5 (-190).

While Cincinnati is just 4-11 in the past 15 games as a favorite, and 3-5 in the past 8 on the run line as a favorite, one of those covers was in the most recent meeting with Cleveland on Aug. 16.

Over/Under

The UNDER 8 (-115) might be the best play on the board.

While Giolito scares me due to his penchant for serving up homers, and a lot of them, the Guardians offense has managed a total of just 2 runs in the past 2 games, while the total has gone low in 4 of the past 5 games overall.

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Cincinnati Reds at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Cincinnati Reds at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Cincinnati Reds (10-26) and Cleveland Guardians (16-18) close out their 2-game Buckeye State series Wednesday with a 6:10 p.m. ET game at Progressive Field. Let’s analyze Tipico Sportsbook‘s lines around the Reds vs. Guardians odds with MLB picks and predictions.

Season series: Cleveland leads 2-1.

The Reds won Tuesday 5-4 and have won 6 of their last 9 games. They own a fine 3.83 ERA since May 8.

Cleveland has lost 4 of its last 5. The Guardians own a 4.88 ERA since April 22 and Cleveland starters own a 5.68 ERA since that date.

Reds at Guardians projected starters

RHP Tyler Mahle vs. RHP Cal Quantrill

Mahle (2-4, 5.89 ERA) has notched a 1.47 WHIP, 4.4 BB/9 and 9.8 K/9 across 36 2/3 IP in 8 starts.

  • Is coming off a sharp effort (2 R, 1 BB, 8 K in 6 IP) vs. the Pittsburgh Pirates.
  • Has been beaten up by a .324 batting average on balls in play and a 56.2% left-on-base rate.
  • Registered a 2.30 ERA, 1.04 WHIP on the road last season.

Quantrill (1-2, 3.93 ERA) has made 6 starts, logging a 1.28 WHIP, 3.9 BB/9 and 5.2 K/9 in 34 1/3 IP.

  • Has benefitted from a .257 BABIP and a low 5% rate of fly balls landing as home runs.

Reds at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:06 a.m. ET.

  • Money line: Reds +115 (bet $100 to win $115) | Guardians -140 (bet $140 to win $100)
  • Run line (RL): Reds +1.5 (-180) | Guardians -1.5 (+145)
  • Over/Under (O/U): 7.5 (O: -110 | U: -110)

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Reds at Guardians picks and predictions

Prediction

Reds 4, Guardians 3

Money line

Looking at the pitching for the price, CINCINNATI (+115) is the top play here. Mahle swings the value-meter to the visitors.

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Run line/Against the spread

The Under has had some push in early betting, and the Cincy money line would be worth investigating but its drowned out by a lot of juice. PASS.

Over/Under

Both sides have some surface batting stats and run-scoring numbers not fully supported by advanced analytics and batted-ball metrics. Cleveland’s offense hasn’t been terribly productive at home; the same applies for Cincinnati’s bats on the road.

BACK THE UNDER 7.5 (-110).

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Cincinnati Reds at Cleveland Guardians odds, picks and predictions

Analyzing Tuesday’s Cincinnati Reds at Cleveland Guardians odds and lines, with MLB expert picks and predictions.

The Cincinnati Reds (9-26) and Cleveland Guardians (16-17) meet in an abbreviated 2-game I-71 series which kicks Tuesday at 6:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Reds vs. Guardians odds with MLB picks and predictions.

Season series: Cleveland leads 2-0.

The Reds are coming off back-to-back losses at the Pittsburgh Pirates Saturday and Sunday, but they are still 5-3 in their last 8 games. The 5 wins are more than Cincinnati had in its first 27 games, when the Reds opened an anemic 4-23.

Cleveland dropped 2 of 3 at the Minnesota Twins last weekend, but the Guardians are back at home where they are 7-2 in their last 9 games. Over those 9 contests, Cleveland scored 50 runs.

Reds at Guardians projected starters

RHP Connor Overton vs. RHP Zach Plesac

Overton (1-0, 1.59 ERA) is tabbed for his 4th start. He has a 1.06 WHIP, 3.2 BB/9 and 4.2 K/9 in 17 IP.

  • Pitched 6 1/3 scoreless innings Thursday at Pittsburgh.
  • Has benefited from a .250 batting average on balls in play.

Plesac (1-3, 4.68 ERA) has made 6 starts. He owns a 1.35 WHIP, 2.8 BB/9 and 5.5 K/9 in 32 2/3 IP.

  • Has coughed up 17 runs over his last 15 IP.

Reds at Guardians odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:56 a.m. ET.

  • Money line: Reds +135 (bet $100 to win $135) | Guardians -170 (bet $170 to win $100)
  • Run line (RL): Reds +1.5 (-155) | Guardians -1.5 (+125)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Reds at Guardians picks and predictions

Prediction

Guardians 4, Reds 2

Money line

The Reds have been woeful on the road, going 4-17 in their first 21 games away from home. Cleveland is the lean in principle, but STEER CLEAR of any tag higher than -165.

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Run line/Against the spread

CLEVELAND -1.5 (+125) is the advisable play here. But the run line favorite on a likable low total can be a tricky proposition. Consider a partial-unit play.

Since 2020, Plesac owns a 4.50 ERA on the road and a 3.63 figure at home.

Over/Under

Both sides have some surface batting stats and run-scoring numbers not fully supported by advanced analytics and batted-ball metrics. Cleveland’s offense hasn’t been terribly productive at home; the same applies for Cincinnati’s bats on the road. Mix in fresh bullpen arms and a slight inward breeze in the  Cleveland weather forecast, and a lower-scoring game here gets the lean.

BACK THE UNDER 7.5 (+105).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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