Chicago Cubs at New York Yankees odds, picks and predictions

Analyzing Saturday’s Chicago Cubs at New York Yankees odds and lines, with MLB expert picks, predictions and best bets.

The Chicago Cubs (41-46) and New York Yankees (48-41) play game 2 of their 3-game series in the Bronx Saturday. First pitch at Yankee Stadium is slated for 1:05 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cubs vs. Yankees and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 1-0; Yankees swept 3-0 in 2022

The Cubs are 3-2 on their current 7-game road trip after shutting out the Yankees 3-0 Friday — behind RHP Jameson Taillon (W, 8 IP, 0 ER, 1 H). The Cubs are averaging 5 runs per game over their last 5. They are 14-14 during interleague play this season.

The Yankees are 2-3 on their current 7-game homestand, winning the first 2 before dropping 3 in a row with Friday’s loss. They have struggled to score, plating just 4 runs in the 3-game skid and producing 3.6 runs per game over their last 5. New York is 13-8 in interleague play.

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Cubs at Yankees projected starters

LHP Drew Smyly vs. RHP Gerrit Cole

Smyly (7-5, 4.10 ERA) will make his 18th start. He has a 1.31 WHIP, 3.0 BB/9 and 7.6 K/9 in 90 innings.

  • Last start: No-decision, 3 2/3 IP, 3 ER, 4 H, 3 BB, 5 K in 8-6 loss at Milwaukee Brewers Monday
  • Last regular-season start vs Yankees: No-decision, 6 IP, 1 ER, 4 H, 2 BB, 3 K in 5-3 home loss Sept. 20, 2016 as member of Tampa Bay Rays
  • 2023 away splits: 4-3, 3.08 ERA (49 2/3 IP, 17 ER), 1.37 WHIP, 6.7 K/9, .257 opponent batting average (OBA) in 9 starts

Cole (8-2, 2.79 ERA) will make his 19th start. He has a 1.14 WHIP, 2.7 BB/9 and 9.7 K/9 in 109 2/3 innings.

  • Last start: Loss, 6 IP, 2 ER, 6 H, 2 BB, 5 K in 5-1 loss at St. Louis Cardinals Sunday
  • Last start vs Cubs: Win, 6 IP, 2 ER, 3 H, 1 BB, 12 K in 6-5 home victory May 27, 2019 as member of Houston Astros
  • 2023 home splits: 5-1, 2.82 ERA (67 IP, 21 ER), 1.10 WHIP, 10.3 K/9, .214 OBA in 11 starts

Cubs at Yankees odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:24 a.m. ET.

  • Moneyline (ML): Cubs +168 (bet $100 to win $168) | Yankees -200 (bet $200 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs +1.5 (-125) | Yankees -1.5 (+104)
  • Over/Under (O/U): 8 (O: -122 | U: +100)

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Cubs at Yankees picks and predictions

Prediction

Yankees 4, Cubs 2

Moneyline

AVOID

The Yankees (-200) get back on track in this one with their ace Cole on the hill. There’s a reason the juice will cost 2 units to win 1 in this one. AVOID and look to the run line.

Run line/Against the spread

BET YANKEES -1.5 (+104).

While I wish the odds were a little better, I’ll still take the Yankees to cover this run line.

Cole has owned the Cubs in his career. In his last 5 starts against Chicago, he is 3-1 with a 1.03 ERA with 40 strikeouts in 35 innings. Plus, as mentioned, he has only 1 loss at home this season..

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Over/Under

AVOID, but I am leaning Under 8 (-105). I may put half a unit on this, but I’m not in love with it.

The reason for considering a small bet is because Cole has allowed more than 2 earned runs just once in his last 6 starts, and Smyly has a great history against the Yankees, having not allowed more than 2 earned runs in any of his last 5 starts against New York.

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