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The Chicago Bears and Buffalo Bills meet at Highmark Stadium Friday. Kickoff is scheduled for 1 p.m. ET (NFL Network/NFL+). Below, we analyze BetMGM Sportsbook’s lines around the Bears vs. Bills odds, and make our expert NFL picks and predictions.
The Bears opened their preseason slate last week in the Hall of Fame Game in Canton, Ohio. They beat the Texans 21-17 in a weather-shortened game as 2.5-point underdogs. However, most books voided full-time bets since 55 minutes were not played, as per the industry standard.
The Buffalo Bills begin their preseason play with a lot of questions after a ton of roster changeover this offseason, but one thing is certain, QB Josh Allen will be the starter. They finished last season 11-6, losing in the divisional round to the Kansas City Chiefs.
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Bears at Bills odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:55 a.m. ET.
- Moneyline (ML): Bears +125 (bet $100 to win $125) | Bills -150 (bet $150 to win $100)
- Against the spread (ATS): Bears +2.5 (-110) | Bills -2.5 (-110)
- Over/Under (O/U): 38.5 (O: -110 | U: -110)
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Bears at Bills picks and predictions
Prediction
Bears 24, Bills 20
Moneyline
We’ve seen the Bears play in the Hall of Fame Game and look competent on offense without their star No. 1 overall pick QB Caleb Williams suiting up. He will see his 1st action in this game in Orchard Park.
Allen and his offense will get around a quarter of action against a Bears defense which allowed Texans QB Davis Mills to put up 17 points in the 1st half. I like the Bills to get up early, but with the combination of Bears QBs Brett Rypien and Tyson Bagent to come back and win it in the 2nd half.
BET BEARS (+125).
Against the spread
I’m not touching a point spread in a preseason game; it’s just too volatile to get reasonable trends. You will continue to see vanilla offenses and defenses.
PASS.
Over/Under
Nine of the 16 games in preseason Week 1 last year had totals of Over 37. The Bears and Texans hit 38 points in a weather-shortened game.
As I mentioned above, Allen should get enough work to put up some points early. I love the fact that Rypien and Bagent are battling for the No. 2 spot on the depth chart, which means they’ll be out there looking to score every drive.
BET OVER 38.5 (-110).
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