Cleveland Cavaliers at New Orleans Pelicans odds, picks and predictions

Analyzing Wednesday’s Cleveland Cavaliers at New Orleans Pelicans odds and lines, with NBA expert picks, predictions and best bets.

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The Cleveland Cavaliers (8-0) and New Orleans Pelicans (3-5) meet Wednesday at Smoothie King Center. Tip-off is scheduled for 8 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Cavaliers vs. Pelicans odds and make our expert NBA picks and predictions for the best bets.

Season series: First meeting; tied 1-1 in 2023-24

The Cavaliers swept a home-and-home set with the Milwaukee Bucks, including a 116-114 victory Monday. It was Cleveland’s first non-cover after a 7-0 against the spread (ATS) start, while the Over has cashed in 3 of the past 4 outings.

The Pelicans suffered a 118-100 loss to the Portland Trail Blazers as a 1-point favorite Monday as the Under (218.5) cashed. New Orleans has lost 5 of the past 6 outings with the Over 4-2 in that span. The Over is 3-0 in 3 games against Eastern Conference teams, too, while going 2-1 SU/ATS in those outings.

Cavaliers at Pelicans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NBA odds. Lines last updated at 6:11 a.m. ET.

  • Moneyline (ML): Cavaliers -300 (bet $300 to win $100) | Pelicans +240 (bet $100 to win $240)
  • Against the spread (ATS): Cavaliers -7.5 (-110) | Pelicans +7.5 (-110)
  • Over/Under (O/U): 224.5 (O: -110 | U: -110)

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Cavaliers at Pelicans key injuries

Cavaliers

  • G Caris LeVert (knee) questionable
  • F Max Strus (ankle) out
  • G Jaylon Tyson (hip) questionable
  • D Dean Wade (illness) out

Pelicans

  • G Jordan Hawkins (back) questionable
  • F Herbert Jones (shoulder) out
  • G C.J. McCollum (adductor) out
  • F Trey Murphy (hamstring) out
  • G Dejounte Murray (hand) out
  • F Zion Williamson (hamstring) questionable

For most recent updates: Official NBA injury report.

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Cavaliers at Pelicans picks and predictions

Prediction

Cavaliers 117, Pelicans 109

Moneyline

You can’t back the Cavaliers (-300) at 3 times your potential return. That’s way too expensive at this price, whether as a straight-up bet or as a multi-leg parlay.

PASS, and look to the spread instead.

Against the spread

The CAVALIERS -7.5 (-110) are worth playing lightly on the road in the Big Easy.

Winning by 4 buckets or more is a tall order, especially away from home. But, the Pelicans +7.5 (-110) have dropped 5 of the past 6 games, while going just 1-6 ATS in the previous 7 outings. That includes back-to-back losses and non-covers against the visiting Atlanta Hawks and Trail Blazers.

Over/Under

OVER 224.5 (-110) is again worth a look, but go at it rather lightly.

The Over has connected in 4 of the past 6 games for the Pelicans, while going 3-0 against Eastern Conference teams.

The Cavs have cashed high in 3 of the past 4 outings, while going for 113 or more points in 7 of 8 games to date. Cleveland has faced just one Western Conference opponent, cashing the Over (226.5) on Oct. 30 in a 134-110 victory over the LA Lakers.

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