When could Cardinals OL Jonah Williams return from his knee injury?

Williams is rehabbing and hoping to come back as early as November. He might not come back at all this season.

The Arizona Cardinals have missed starting right tackle Jonah Williams. The veteran who signed a two-year, $30 million deal this offseason has played only one quarter of football. He injured his knee on the final play of the first quarter of the Cardinals’ season-opening loss to the Buffalo Bills.

Is he coming back this season?

It isn’t known. Head coach Jonathan Gannon said last week, “We’ll see,” which is never lends itself to something positive.

ESPN’s Jeremy Fowler reports his return is uncertain.

Williams is rehabbing the injury with the goal of returning later this season, but it is possible he is unable to return. It will depend on the response to the rehab.

Fowler says he is eyeing a potential return next month in November but that is “up in the air.”

In the meantime, Kelvin Beachum has started two games and missed one with a hamstring injury. They have no other backup tackle on the active roster. Charlie Heck is on the practice squad and rookie Christian Jones is on injured reserve but has had his practice window opened so he will be activated in the next three weeks.

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49ers favored in Week 9 with questions surrounding Cardinals health

Kyler Murray might not play for the Cardinals on Sunday, which is a big reason the #49ers are favored.

Neither the 49ers nor the Cardinals are the picture of health going into their Week 9 matchup, but San Francisco might wind up having the edge on the injury front and in the game.

While question marks hang over 49ers wide receiver Deebo Samuel and running back Elijah Mitchell, the Cardinals have quarterback Kyler Murray and wide receiver DeAndre Hopkins both listed as ‘questionable’ after missing practice all week. The result of the potential absences on both sides is the 49ers getting favored at home against the 7-1 Cardinals.

Tipico Sportsbook has San Francisco favored by 2.5 points.

This signals the book either expects Murray not to play, or anticipates him being a shell of himself because of an ankle injury he suffered last week against the Packers. Not to mention the state of Hopkins’ hamstring which could either keep him out or limit his effectiveness.

It’s worth noting too how well the 49ers played a healthier version of the Cardinals in Arizona. Defensive lineman JJ Watt for had a monster game for the Cardinals and he’s already been ruled out with a shoulder issue. Even a fully healthy Cardinals squad probably wouldn’t have been heavily favored in Santa Clara, and the injury questions combined with the performance the 49ers had against the Bears were enough to swing the line in favor of the home team Sunday.

This is a huge game for the 3-4 49ers. Getting back to .500 with a win over a division opponent would buoy their playoff hopes and give them a little bit of wiggle room in Week 10 when they host the Rams.

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