St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Wednesday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (70-69) and Milwaukee Brewers (81-58) play the finale of a 3-game series Wednesday at American Family Field at 7:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Brewers lead 8-4

The Cards outlasted the Brewers 7-4 in 12 innings Tuesday. They took the lead in the 11th but couldn’t close it out. OF Michael Siani nearly made a highlight-reel catch to end it, but he couldn’t hang on. He took matters into his hands at the dish, though, with a 2-run single in the 12th. The Cards remain 5½ out of the last Wild Card spot.

The Brew Crew can cruise, up 10 in the division with a magic number at 13 to clinch. SS Willy Adames ended his 5-game homer streak Tuesday, but he did have an RBI in the game. They are 19-11 in their last 30 games despite a litany of injuries.

Cardinals at Brewers projected starters

RHP Sonny Gray vs. RHP Colin Rea

Gray (12-9, 3.96 ERA) makes his 26th start. He has a 1.10 WHIP, 2.2 BB/9 and 10.9 K/9 in 147 2/3 IP.

  • Last start: Win, 6 IP, 1 ER, 3 H, 0 BB, 4 K in 4-1 home victory Thursday against San Diego Padres
  • Last 5 regular-season starts vs. Brewers: 1-4, 4.68 ERA, 1.24 WHIP, 35 K in 25 IP

Rea (12-4, 3.70 ERA) makes his 24th start (27th appearance). He has a 1.16 WHIP, 2.2 BB/9 and 7.3 K/9 in 146 IP.

  • Last start: No-decision, 4 IP, 3 ER, 6 H, 0 BB, 5 K in 5-4 victory in 10 innings Friday at Cincinnati Reds
  • Last 5 starts vs. Cardinals: 0-2, 4.22 ERA, 1.69 WHIP, 15 K in 21 1/3 IP

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cardinals at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:40 p.m. ET.

  • Moneyline (ML): Cardinals -105 (bet $105 to win $100) | Brewers -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+165) | Brewers +1.5 (-200)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Cardinals at Brewers picks and predictions

Prediction

Cardinals 4, Brewers 2

Moneyline

The Cards have gone 3-0-1 in their last 4 series — and all were against playoff teams. They’re fighting, and they’re going to need to get length out of Gray today. Their top 4 relievers all pitched Tuesday and combined for 5 1/3 IP.

Gray goes a solid 7, and the offense grinds its way.

Take the CARDINALS -105.

Run line/Against the spread

As mentioned, the team HAS to get length out of Gray. It’s a bit juice-laden, but I’m on board with SONNY GRAY OVER 17.5 OUTS (-165).

Over/Under

We have similar conditions to Tuesday, which would have gone Under if extra innings weren’t needed. It’s 76 degrees with a 9-mph breeze blowing in.

The Under has cashed in Gray’s last 5 starts, and I’ll take the UNDER 8 (-115).

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Tuesday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (69-69) and Milwaukee Brewers (81-57) play the 2nd game of a 3-game series Tuesday at American Family Field at 7:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Brewers lead 8-3

The Cards were pounded 9-3 by the Brewers Monday as they allowed 8 walks and 3 homers. C Pedro Pages did his part by hitting 2 homers, but the pitching staff was atrocious. The Cards are 5½ out of a Wild Card spot.

The Brewers have won 6 of 7, thanks in part. LF Jackson Chourio delivered the big blow Monday with a grand slam. They’ve won 20 of 30 to open a 10-game lead over the Chicago Cubs in the NL Central. They’ve also dominated the NL Central at 30-17.

Cardinals at Brewers projected starters

LHP Steven Matz vs. RHP Aaron Civale

Matz (1-2, 6.18 ERA) makes his 7th start. He has a 1.73 WHIP, 3.6 BB/9 and 5.5 K/9 in 27 2/3 IP. The 10-year veteran was activated off the 60-day IL after missing 4 months with back issues

  • Last start: No-decision, 3 1/3 IP, 4 ER, 7 H, 2 BB, 1 K in 11-6 loss at Detroit Tigers April 30
  • Career vs. Brewers: 5-2, 2.89 ERA (43 2/3 IP, 14 ER), 1.03 WHIP, 7.0 K/9 in 8 games (7 starts)
  • Last 5 regular-season starts vs. Brewers: 4-1, 2.43 ERA (29 2/3, 8 ER), 1.01 WHIP, 21 K

Civale (5-8, 4.59 ERA) makes his 27th start. He has a 1.34 WHIP, 3.1 BB/9 and 8.4 K/9 in 135 1/3 IP with Tampa Bay Rays and Brewers. Since his July 3 trade to Milwaukee, the Northeastern University product is 3-2 with a 3.72 ERA (48 1/3 IP, 20 ER), 1.28 WHIP, 3.5 BB/9, 8.0 K/9 in 9 starts.

  • Last start: Win, 7 IP, 0 ER, 2 H, 2 BB, 7 K in 6-0 home victory vs. San Francisco Giants Thursday
  • Career vs. Cardinals: 1 road start for Cleveland, loss, 6 IP, 5 ER, 8 H, 2 BB, 3 K in 7-2 setback Aug. 30, 2020

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cardinals at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:11 p.m. ET.

  • Moneyline (ML): Cardinals +125 (bet $100 to win $125) | Brewers -150 (bet $150 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-175) | Brewers -1.5 (+145)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Cardinals at Brewers picks and predictions

Prediction

Brewers 5, Cardinals 3

Moneyline

The Brewers have dominated the Cardinals the last 2 years, going 16-8 against them. Matz is making his first start since April, and the moderate favorites are the way to go here.

TAKE BREWERS (-150).

Run line/Against the spread

PASS since we’re backing the Brewers ML.

Meanwhile, 1B Rhys Hoskins hit his 23rd homer of the season Monday. He has 4 career hits against Matz in 23 at-bats, and 3 of them left the ballpark.

LET’S TAKE RHYS HOSKINS OVER 1.5 H+R+RBI (+115).

Over/Under

We’re slated to have a 72-degree evening with a 9-mph gust blowing in from right-center. I trust the Brewers to score 5, but I don’t trust the Cards to score more than 3 in order to cash an Over. They’ve scored more than 3 runs just twice in the last 9 meetings with Milwaukee.

LEAN UNDER 8.5 (-115).

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Monday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (69-68) and Milwaukee Brewers (80-57) begin a 3-game series Monday. First pitch from American Family Field is set for 2:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Brewers lead 7-3

The Cardinals won for the 4th time in 5 games with a 14-7 victory as +213 underdogs at the New York Yankees Sunday with the Over (9.5) hitting. RF Jordan Walker went 5-for-5 with a 2-run blast in the 5th inning for the Cardinals, who had 21 hits. St. Louis also got 2-run homers from DH Luken Baker and LF Lars Nootbaar. It is 33-36 away from Busch Stadium.

Milwaukee had its 5-game win streak snapped in a 4-3 loss in 11 innings at the Cincinnati Reds Sunday. The Brewers could only manage 6 hits on the afternoon, one being a solo shot from SS Willy Adames. 2B Brice Turang also notched his 40th stolen base of the season. They are 40-26 at home.

Cardinals at Brewers projected starters

RHP Andre Pallante vs. RHP Freddy Peralta

Pallante (6-6, 3.80 ERA) makes his 16th start and 25th appearance. He has a 1.32 WHIP, 3.4 BB/9 and 6.6 K/9 in 92 1/3 IP.

  • Last start: No-decision, 5 2/3 IP, 2 ER, 8 H, 2 BB, 3 K in 4-3 home victory against San Diego Padres Wednesday
  • 2024 away splits: 2-2, 2.86 ERA (44 IP, 14 ER), 1.18 WHIP, 6.5 K/9 in 12 appearances (7 starts)
  • Career vs. Brewers: 0-0, 4.08 ERA (17 2/3 IP, 8 ER), 1.64 WHIP, 4.6 K/9 in 12 relief appearances

Peralta (9-7, 3.70 ERA) makes his 28th start. He has a 1.19 WHIP, 3.4 BB/9 and 10.4 K/9 in 148 1/3 IP.

  • Last start: Win, 6 IP, 0 ER, 2 H, 3 BB, 8 K in 5-3 home victory against San Francisco Giants Wednesday
  • 2024 home splits: 5-4, 3.97 ERA (79 1/3 IP, 35 ER), 1.14 WHIP, 10.4 K/9 in 15 starts
  • 2024 vs Cardinals: 0-0, 1.59 ERA (17 IP, 3 ER), 1.18 WHIP, 9.0 K/9 in 3 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cardinals at Brewers odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:48 a.m. ET.

  • Moneyline (ML): Cardinals +140 (bet $100 to win $140) | Brewers -166 (bet $166 to win $100)
  • Run line (RL)/Against the spread: Cardinals +1.5 (-160) | Brewers -1.5 (+130)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Cardinals at Brewers picks and predictions

Prediction

Brewers 5, Cardinals 3

Moneyline

PASS.

The Brewers (-166) will take the opener of this series in Milwaukee, but I’d rather put my wager on the run line.

Run line/Against the spread

BET BREWERS -1.5 (+130).

Milwaukee is kicking off a 6-game homestand and has been pretty solid at American Family Field this season (40-25 straight up). Milwaukee’s been hot lately, winning 5 of its last 6 games. Plus, Peralta, has been lights out with a 2-0 record in his last 3 starts, giving up just 1 earned run over 17 innings. Even though the Cardinals are playing well, the Brewers have had the upper hand, going 7-3 against St. Louis this year. So, taking the Brewers -1.5 seems like a smart move!

Over/Under

PASS.

The market does not expect a lot of runs with this low total, and I agree, but I’m not confident enough to recommend this bet. I don’t like the trends in either direction.

These teams are 5-5 O/U in the last 10 meetings. The Cardinals are 5-5 O/U in their last 10 games, while the Brewers are 6-3-1 O/U in their last 10.

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Saturday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (15-23) and Milwaukee Brewers (23-15) play the 3rd game of a 4-game set at American Family Field Saturday. First pitch is scheduled for 7:15 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Brewers lead 5-0

The Cardinals have lost 6 straight and are coming off an 11-2 loss at the Brewers Friday with the Over (8.5) hitting. Cardinals 2B Nolan Gorman hit a solo shot in the 9th for St. Louis, which failed to cash as a +113 underdog.

The Brewers cashed as -123 favorites behind 6 shutout innings from LHP Robert Gasser in his MLB debut. SS Willy Adames hit 3 doubles for the Brewers, who have won 7 straight against the Cardinals.

Cardinals at Brewers projected starters

RHP Kyle Gibson vs. RHP Freddy Peralta

Gibson (2-2, 3.68 ERA) makes his 8th start. He has a 1.18 WHIP, 3.3 BB/9 and 6.8 K/9 in 44 innings.

  • Last start: No-decision, 6 IP, 2 ER (3 R), 7 H, 2 BB, 4 K in 4-3 home setback vs. New York Mets Monday
  • 2024 road stats: 1-1, 3.15 ERA (20 IP, 7 ER), 1.05 WHIP in 3 starts
  • 2023 vs. Brewers: 0-0, 3.60 ERA (5 IP, 2 ER), 5 H, 2 BB, 7 K in 1 start, a 4-3 road loss in 10 innings with Baltimore Orioles June 6
  • Career vs. Brewers: 1-2, 4.97 ERA (50 2/3 IP, 28 ER), 1.52 WHIP in 9 starts

Peralta (3-1, 3.49 ERA) makes his 8th start. He has a 0.98 WHIP, 3.5 BB/9 and 11.6 K/9 in 38 2/3 innings.

  • Last start: Loss, 5 IP, 3 ER, 3 H, 6 BB, 5 K in 5-0 defeat at Chicago Cubs Sunday
  • 2024 home stats: 1-0, 4.09 ERA (11 IP, 5 ER), 0.55 WHIP in 2 starts
  • 2023 vs. Cardinals: 1-2, 4.15 ERA (17 1/3 IP, 8 ER), 1.27 WHIP in 3 starts
  • Career vs. Cardinals: 3-6, 5.32 ERA (64 1/3 IP, 38 ER), 1.37 WHIP in 12 starts and 4 relief appearances

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Cardinals at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:55 a.m. ET.

  • Moneyline (ML): Cardinals +145 (bet $100 to win $145) | Brewers -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-145) | Brewers -1.5 (+120)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Cardinals at Brewers picks and predictions

Prediction

Brewers 3, Cardinals 2

Moneyline

Milwaukee (-175) has outscored the Cardinals 18-3 over the last 2 games and should hand them their 7th straight loss. However, with Gibson on the mound for St. Louis, -175 is a steep price to pay on the Brewers.

PASS. Bet the run line and/or total instead.

Run line/Against the spread

Gibson’s stats are skewed after giving up a total of 13 runs over his 1st 3 starts this season. He has allowed 2 or fewer earned runs in 4 straight starts, and the Cardinals have outscored opponents 13-6 over that span.

St. Louis is also a respectable 8-7 on the run line as a road underdog this season and should bounce back after 2 straight embarrassing losses.

BET CARDINALS +1.5 (-145).

Over/Under

Milwaukee is the best Over bet in the league this season at 23-14-1 (62.2%). However, the last 5 games Gibson has started have all ended with fewer than 7.5 total runs scored.

I’m personally only betting the run line, but if I were forced to play this total, I would take the Under and hope that Gibson bounces back after an average start last time out against the Mets.

LEAN UNDER 7.5 (-105).

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Thursday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (15-21) and Milwaukee Brewers (21-15) open a 4-game set Thursday. First pitch from American Family Field is scheduled for 7:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Brewers lead 3-0

St. Louis has lost 4 games in a row after falling 7-5 against the New York Mets Tuesday and failing to cash as a -120 home favorite. DH Alec Burleson led the way on offense with 2 RBIs, while 4 different Cardinals players had at least 1 RBI. RHP Miles Mikolas allowed 6 earned runs in 4 innings to pick up the loss.

Milwaukee fell 6-4 against the Kansas City Royals Wednesday while failing to cash as a +106 road underdog. C William Contreras led the offense with 2 RBIs, and 3 different Brewers players had at least 1 RBI, including 1B Gary Sanchez who hit a solo shot in the 7th. RHP Joe Ross allowed 3 earned runs in 5 innings and picked up the loss.

Cardinals at Brewers projected starters

RHP Sonny Gray vs. RHP Tobias Myers

Gray (4-1, 0.89 ERA) makes his 6th start. He has a 0.86 WHIP, 1.5 BB/9 and 11.3 K/9 in 30 1/3 innings.

  • Last start: Win, 7 IP, 0 ER, 3 H, 1 BB, 6 K in 3-0 home victory vs. Chicago White Sox Friday
  • Cardinals are 4-1 in his starts
  • Has allowed 2 ER or fewer in each start
  • Has allowed 3 ER (1 HR) this season while striking out 38 and walking 5

Myers (0-2, 6.23 ERA) makes his 4th start. He has a 1.31 WHIP, 3.5 BB/9 and 7.6 K/9 in 13 innings.

  • Last start: Loss, 3 IP, 4 ER, 3 H, 4 BB, 2 K in 6-5 loss at Chicago Cubs Saturday
  • Brewers are 0-3 in his starts
  • Has allowed 4 ER in back-to-back starts
  • Has allowed 9 ER (5 HR) while striking out 11 and walking 5

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Cardinals at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11 a.m. ET.

  • Moneyline (ML): Cardinals -135 (bet $135 to win $100) | Brewers +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+125) | Brewers +1.5 (-155)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Cardinals at Brewers picks and predictions

Prediction

Cardinals 4, Brewers 3

Moneyline

BET CARDINALS (-135).

St. Louis has struggled of late, but its ace Gray is the reason it is the favorite. Gray has allowed just 3 earned runs total this season and faces a Brewers squad that has lost 4 of its last 5 games. The Cardinals have scored 5 runs twice in their last 4 games, which is plenty of separation for Gray on the mound.

Run line/Against the spread

PASS.

The moneyline is the better option in this matchup.

Over/Under

BET UNDER 8 (-115).

With Gray’s previous track record and the Cardinals scoring 3 or fewer runs in 4 of their last 6 games, the Under is worth a wager. The Cardinals have hit the Under in 2 of their last 3 games and 6 of their last 9, while the Brewers have failed to the Over in 4 of their last 7.

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Saturday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (2-5) will take on the Milwaukee Brewers (6-1) in the 2nd game of a 3-game series on Saturday at American Family Field. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Brewers lead 1-0.

The Cardinals were shut out 4-0 by the Brewers Friday with RHP Jack Flaherty issuing 6 BB, giving him 13 BB in 2 starts this season. St. Louis has lost 4 consecutive games and has been outscored 21-7 in those games.

RHP Brandon Woodruff recorded 4 K, 2 BB, and 0 ER in 5 1/3 IP in Friday’s win. Milwaukee has strung together 6 straight wins after losing on Opening Day to the Chicago Cubs.

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Cardinals at Brewers projected starters

LHP Jordan Montgomery vs. LHP Eric Lauer

Montgomery (1-0, 5.40 ERA) makes his 2nd start. He has a 1.40 WHIP, 1.8 BB/9 and 5.4 K/9 through 5 IP.

  • Was credited with the win in his season debut despite allowing 6 H and 3 ER to the Toronto Blue Jays Apr. 2.
  • Has allowed 2 ER or more in 5 straight starts for the Cardinals dating back to last season.

Lauer (1-0, 3.38 ERA) makes his 2nd start. He has a 1.31 WHIP, 3.4 BB/9 and 10.1 K/9 through 5 1/3 IP.

  • Tallied 6 K, 5 H, 2 BB, and 2 ER in an 89-pitch outing against the Chicago Cubs on Apr. 2.
  • Has a 2-3 record with a 6.46 ERA, 1.63 WHIP, and only a 5.3 K/9 in 6 career starts against the Cardinals.

Cardinals at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:40 a.m. ET.

  • Moneyline (ML): Cardinals -145 (bet $145 to win $100) | Brewers +120 (bet $100 to win $120)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+110) | Brewers +1.5 (-135)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Cardinals at Brewers picks and predictions

Prediction

Cardinals 6, Brewers 4

Moneyline

With the success that St. Louis has had against Lauer in his career, I’ll back the CARDINALS (-145) on the road despite the recent struggles. I would bet the Cardinals’ money line up to -150 odds.

Run line/Against the spread

CARDINALS -1.5 (+110) has decent value with how well St. Louis performs against southpaws. The Cardinals slashed .263/.343/.465 against lefties in 2022 and have most of their lineup back this season.

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Over/Under

OVER 8.5 (-115) is the play in this game with both teams having average lefties on the mound. The Brewers haven’t excelled against southpaws in recent years, but they have a different lineup than last season.

There have been 9-plus runs scored in 3 of the 4 home games the Brewers have played this season.

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Friday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (2-4) and Milwaukee Brewers (5-1) renew their Central Division rivalry with the opener of a 3-game set Friday at American Family Field. First pitch is at 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: 1st meeting; St. Louis won 10-9 in 2022.

The Cardinals were overpowered by the visiting Atlanta Braves and outscored 17-7 in a 3-game sweep earlier in the week. The Cardinals have been Jekyll & Hyde out of the gate as they nearly swept the visiting Toronto Blue Jays to start the season if not for a season-opening bullpen meltdown.

The Brewers finished off a 3-game home sweep of the New York Mets with a 7-6 win Wednesday. The Brewers outscored the Mets 26-6 in the set, which included consecutive shutouts. 3B Brian Anderson, an offseason free-agent signing, has been dominant, hitting .500 with 3 homers and 10 RBIs in the first 6 games.

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Cardinals at Brewers projected starters

RHP Jack Flaherty vs. RHP Brandon Woodruff

Flaherty (1-0, 0.00 ERA) makes his 2nd start of 2023. He threw 5 hitless, shutout innings and struck out 4 but walked an astounding 7 batters in a 4-1 home victory vs. the Blue Jays Saturday.

  • Had similar shaky start against Milwaukee when he returned from injury last June, allowing 2 earned runs on 3 hits and 5 walks with 2 K’s in 3 innings of a no-decision, which Cards won 6-2
  • Brewers are hitting .290 with a .431 wOBA in 79 plate appearances against Flaherty

Woodruff (0-0, 1.50 ERA) makes his 2nd start. He allowed 1 earned run on 3 hits and a walk, while fanning 8 in 6 innings of a no-decision at the Chicago Cubs Sunday, which Milwaukee won 3-1.

  • Last 5 starts vs. Cards: 2-2, 1.80 ERA (25 IP, 5 ER), 0.96 WHIP, 29 K
  • Cardinals are batting just .190 with a .257 wOBA in 153 plate appearances against Woodruff

Cardinals at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:22 p.m. ET.

  • Moneyline (ML): Cardinals +130 (bet $100 to win $130) | Brewers -155 (bet $155 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-155) | Brewers -1.5 (+125)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Cardinals at Brewers picks and predictions

Prediction

Brewers 4, Cardinals 2

Moneyline

I really like the BREWERS (-155) in this one and am willing to lay the extra juice. Flaherty just hasn’t been the same pitcher since injuries began piling up in 2020 — I believe his opening start was a fluke — and Woodruff has been lights out against the Cards.

TAKE BREWERS (-155).

Run line/Against the spread

I’ll stay away from the RL here out of respect to the Cardinals offense, and I’ll double down on the BREWERS FIRST 5 INNINGS (-165) for the same price. Flaherty has a lot of control issues that he was able to slither away from in his 1st start. He won’t be so lucky Friday.

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Over/Under

I like UNDER 8.5 (-110), though Flaherty could give up 5 or more and make it interesting. As mentioned, Woodruff has allowed 5 runs to the Cards in 25 innings during his last 5 against them.

This O/U line could really be 7.5. The Under is 5-2 in the last 7 between the teams and 4-1-1 in the last 6 in Milwaukee. TAKE UNDER 8.5 (-110).

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Wednesday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks and predictions.

The St. Louis Cardinals (90-65) and Milwaukee Brewers (82-72) close out  a 2-game set Wednesday. First pitch is set for 7:40 p.m. ET at American Family Field. Let’s analyze Tipico Sportsbook‘s lines around the Cardinals vs. Brewers odds with MLB picks and predictions.

Season series: St. Louis leads 10-8

St. Louis won Tuesday’s game 6-2, but is just 3-5 in its last 8 games. The Redbirds own a .620 OPS over that stretch.

The Brewers are 4-2 in their last 6 games. Tuesday’s loss aside, Milwaukee’s offense has notched up a few clicks of late and the Brewers own a .760 OPS since Sept. 10.

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Cardinals at Brewers projected starters

LHP Jose Quintana vs. RHP Brandon Woodruff

Quintana (6-6, 3.03 ERA) is tabbed for his 31st start of the season. He has a 1.22 WHIP, 2.5 BB/9 and 7.4 K/9 in 157 2/3 IP.

  • Has a 1.91 ERA over his last 7 starts
  • Is up against a Milwaukee team that has had trouble against left-handers (.664 OPS)
  • Has logged 100-plus pitches in each of his last 2 starts
  • Owns a 4.13 ERA on the road and a 2.24 ERA at home

Woodruff (12-4, 3.18 ERA) has a 1.09 WHIP, 2.6 BB/9 and 11.0 K/9 through 141 1/3 IP across 25 starts.

  • Has allowed just 2 R in his last 14 IP and owns a 2.44 ERA over his last 7 starts
  • Has held current Cards batters to an aggregate .602 OPS
  • Owns a 1.35 ERA in his last 3 starts at home and a 2.16 home ERA for the season

Cardinals at Brewers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:42 p.m. ET.

  • Money line: Cardinals +133 (bet $100 to win $133) | Brewers -165 (bet $165 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-170) | Brewers -1.5 (+135)
  • Over/Under (O/U): 7.5 (O: +105 | U: -130)

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Cardinals at Brewers picks and predictions

Prediction

Brewers 5, Cardinals 4

Money line

Leaning into some possible Quintana fatigue in this spot. And backing Woodruff and his versus-batter and home-park splits.

Brewer bats have been more reliable of late.

TAKE MILWAUKEE (-165).

Run line/Against the spread

Skip the extra juice, and AVOID this play.

Over/Under

Mixed signals here, but a slight lean on the Over. Consider a partial-unit play on the OVER 7.5 (+105).

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Tuesday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks and predictions.

The St. Louis Cardinals (89-65) and Milwaukee Brewers (82-71) open a 2-game set Tuesday. First pitch is set for 7:40 p.m. ET at American Family Field. Let’s analyze Tipico Sportsbook‘s lines around the Cardinals vs. Brewers odds with MLB picks and predictions.

Season series: St. Louis leads 9-8

St. Louis is 2-4 on a road trip that started with the San Diego Padres and Los Angeles Dodgers. The Cardinals have struggled with the bats on the trip: they’ve logged a slash line of .204/.259/.363 (.623 OPS).

The Brewers are 4-1 in their last 5 games. Milwaukee’s offense has notched up a few clicks of late. The Brewers own a .772 OPS over their last 14 games.

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Cardinals at Brewers projected starters

RHP Miles Mikolas vs. RHP Adrian Houser

Mikolas (11-13, 3.35 ERA) has authored a 1.04 WHIP, 1.8 BB/9 and 6.7 K/9 through 193 1/3 IP across 31 starts.

  • Has held current Milwaukee batters to an aggregate .592 OPS
  • Owns a 4.29 ERA on the road for the season but a 6.06 ERA over his last 6 turns away from home
  • Has been aided by a .249 batting average on balls in play

Houser (6-9, 4.62 ERA) owns a 1.45 WHIP, 3.9 BB/9 and 6.0 K/9 through 99 1/3 IP across 21 games (20 starts).

  • Owns a tidy 2.12 ERA over his last 5 starts against St. Louis
  • Owns a 2.61 ERA over his last 5 starts overall

Cardinals at Brewers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:16 a.m. ET.

  • Money line: Cardinals -112 (bet $112 to win $100) | Brewers -108 (bet $108 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+145) | Brewers +1.5 (-180)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Cardinals at Brewers picks and predictions

Prediction

Cardinals 5, Brewers 4

Money line

Houser has displayed some fatigue signs over recent starts. Velocity is down, and missed bats have dried up.

This is a chance for the Redbirds to get right with the bats, and Mikolas has been solid of late.

TAKE ST. LOUIS (-112). Consider waiting out a better price for full-unit action.

Run line/Against the spread

Skip the extra juice, and AVOID this play.

Over/Under

The Cards were cranking out mid-700s OPS figures much of the first couple weeks of September. For the season, St. Louis has stealthily logged 4.75 runs per game — only 4 teams average more.

Just a sliver of a lean on the OVER 7.5 (-130) here: probably only actionable for more aggressive bettors.

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St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Monday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks and predictions.

The St. Louis Cardinals (38-30) head to American Family Field Monday to start a 4-game series against the Milwaukee Brewers (38-30) at 8:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cardinals vs. Brewers odds with MLB picks and predictions.

St. Louis lost the rubber match of their 3-game interleague series at the Boston Red Sox 6-4 Sunday, but the Cardinals are 6-4 straight up (SU) in their last 10 games.

Milwaukee swept the Reds in a 3-game series in Cincinnati last weekend, but the Brewers are just 5-5 SU in the last 10.

The season series between the NL Central rivals is tied 4-4, but St. Louis has a plus-3 run differential in those meetings.

Cardinals at Brewers projected starters

RHP Miles Mikolas vs. RHP Corbin Burnes 

Mikolas 5-4 with a 2.62 ERA, 0.97 WHIP, 1.7 BB/9 and 7.2 K/9 in 82 1/3 IP over 13 starts.

  • Last start: Won 9-1 at home June 14 vs. the Pittsburgh Pirates with 8 2/3 IP, 1 R (0 ER), 1 H, 1 BB and 6 K. He allowed his 1st hit with 2 outs in the bottom of the 9th inning.
  • 2022 vs. the Brewers: 1-1 with a 5.11 ERA (12 1/3 IP, 7 ER), 12 H, 7 ER, 2 HR, 2 BB and 13 K in 2 starts.

Burnes is 4-4 with a 2.52 ERA, 0.95 WHIP, 1.9 BB/9 and 11.4 K/9 in 78 2/3 IP over 13 starts.

  • Last start: Won 10-2 Wednesday at the New York Mets with 6 IP, 2 ER, 5 H, 1 HR, 0 BB and 8 K.
  • 2022 vs. the Cardinals: One start, an 8-0 win at St. Louis May 29  with 7 scoreless IP, 2 H, 1 BB and 11 K.

Cardinals at Brewers odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:24 a.m. ET.

  • Money line (ML): Cardinals +140 (bet $100 to win $140) | Brewers -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-155) | Brewers -1.5 (+125)
  • Over/Under (O/U): 7.5 (O: -112 | U: -108)

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Cardinals at Brewers picks and predictions

Prediction

Brewers 6, Cardinals 2

Money line

RISK 1 unit on the BREWERS (-175) because they have been steamed up by sharp action and a decisive edge in the pitching matchup.

Nearly 80% of the money is on the Brew Crew whereas 65% of the bets placed are on the Cardinals (+140), per Pregame.com. Typically, you want to follow the cash column of the betting splits since professional bettors are putting up bigger units than your average Joe. Also, Milwaukee’s ML has climbed from the -155 opening number.

Also, starters typically struggle in the game after throwing a no-hitter. While Mikolas technically didn’t complete a no-no, he went 26 outs without allowing a hit and will struggle against a Milwaukee lineup that’s roughed him up once this season.

On the other hand, Burnes’ numbers vs. St. Louis’s lineup are outrageous. Burnes has a 41.5% K% and 82.0 mph exit velocity with a .169/.209/.240 expected batting average, wOBA and slugging percentage slash line in 106 plate appearances vs. active Cardinals hitters, according to Statcast.

If your standard unit is $100 then “flat-BET” that on the BREWERS (-175) to earn a $57.14 profit instead of risking $175 to win $100 because Milwaukee’s ML is expensive.

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Run line/Against the spread

PASS.

Although I’m confident in betting Milwaukee’s ML, there isn’t a big enough gap between these two teams to “sprinkle” on the Brewers -1.5 (+125).

Also, the Cardinals +1.5 (-155) are 13-8 RL as road underdogs and the Brew Crew is 11-15 RL home favorites.

Over/Under

Slight LEAN to the OVER 7.5 (-112) because St. Louis’s lineup is far less productive vs. right-handed pitching and Burnes dominates the Cardinals.

But, St. Louis is 5-0 O/U in the last 5 games and 8-4-1 O/U in Mikolas’ 13 starts and Milwaukee is 4-0 O/U in Burnes’ last 4 starts as a favorite.

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