Buffalo Bills at Houston Texans odds, picks and predictions

Analyzing Sunday’s Buffalo Bills at Houston Texans odds and lines, with expert NFL picks and predictions.

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The Buffalo Bills (3-1) and Houston Texans (3-1) meet Sunday. Kickoff from NRG Stadium is set for 1 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Bills vs. Texans odds, and make our expert NFL picks and predictions.

Buffalo was dismantled 35-10 at the Baltimore Ravens on Sunday Night Football as a 2.5-point underdog. The Bills allowed a whopping 427 yards of total offense, including 199 rushing yards to Ravens RB Derrick Henry. The loss marked the 1st game without a passing TD for QB Josh Allen this year.

Houston escaped with a 24-20 win over the visiting Jacksonville Jaguars Sunday, but failed to cover as a 5.5-point favorite. QB C.J. Stroud completed 27 of his 40 passes for 345 yards with 2 TDs as the Texans amassed 435 yards of offense. WR Nico Collins hauled in 12 receptions for 151 yards and 1 TD.

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Bills at Texans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 3 p.m. ET.

  • Moneyline (ML): Bills +100 (bet $100 to win $100) | Texans -120 (bet $120 to win $100)
  • Against the spread (ATS): Bills +1 (-110) | Texans -1 (-110)
  • Over/Under (O/U): 47 (O: -110 | U: -110)

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Bills at Texans key injuries

Bills

  • LB Terrel Bernard (pectoral) questionable
  • CB Taron Johnson (forearm) questionable
  • DT Ed Oliver (hamstring) out
  • Taylor Rapp (concussion) out
  • WR Khalil Shakir (ankle) out

Texans

  • DE Derek Barnett (shoulder) out
  • RB Joe Mixon (ankle) out
  • RB Dameon Pierce (hamstring) questionable

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Bills at Texans picks and predictions

Prediction

Bills 24, Texans 21

Moneyline

LEAN BILLS (+100).

Houston has the more talented roster, especially offensively, but in close matchups like these, I tend to go with the better quarterback to win. I expect this Buffalo team to see some success in the trenches on both sides of the ball.

This is a lean because, as stated, this is a very tight matchup, and I find it very difficult to gauge either team at this time.

Against the spread

PASS.

I like the Bills to cover here, but I am backing them on the ML and am not a fan of doubling down on 1-point underdogs.

Over/Under

BET UNDER 47 (-110).

The Under has hit in each of Houston’s last 3 games and is 2-1 in Buffalo’s last 3. Both Buffalo and Houston have solid defenses, and I am not sold on Buffalo’s offense, which currently scores 30.5 points per game, as I expect that number to decrease as the Bills play more competition.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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