49ers injury update: WR Brandon Aiyuk carted off with apparent leg injury

Brandon Aiyuk went to the locker room on a cart.

The San Francisco 49ers injury situation at wide receiver is a mess.

With WR Deebo Samuel already in the locker room dealing with an illness, WR Brandon Aiyuk took a low hit on a catch late in the second quarter and had his right knee bend awkwardly. The 49ers quickly ruled Aiyuk out with a knee injury.

Aiyuk was tended to by trainers before limping off to the blue medical tent on the sideline. He was carted off the field at halftime according to reporters at Levi’s Stadium.

The Aiyuk injury leaves the 49ers woefully short on wide receivers. Rookies Ricky Pearsall and Jacob Cowing were on the field with veteran Chris Conley immediately following the Aiyuk injury. Ronnie Bell is the only other WR on the active roster.

It’s unclear what Samuel’s status is as he deals with an illness that limited him to only three snaps in the first half per the Fox broadcast.

Aiyuk had two catches for 23 yards on six targets before exiting Sunday’s game. He’s up to 25 receptions and 374 yards for the season.

The 49ers offense struggled even with Aiyuk on the field in the first half. They had just 131 yards and five first downs at the half. Kansas City took a 14-6 lead into the break.

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