Baltimore Orioles at Chicago Cubs odds, picks and predictions

Analyzing Friday’s Baltimore Orioles at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The Baltimore Orioles (43-25) and Chicago Cubs (31-37) open a 3-game set Friday at Wrigley Field. First pitch is scheduled for 2:20 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting of 2023; Orioles won last season’s series 3-1

The Orioles won 4-2 as -115 home favorites vs. the Toronto Blue Jays Thursday. Baltimore has won 6 of its last 7 games and is 5 games behind the Tampa Bay Rays for the lead in the AL East.

The Cubs won 7-2 as -142 home favorites vs. the Pittsburgh Pirates Thursday. Chicago is on a 3-game win streak and sits 4th in the NL Central, 3.5 games behind the division-leading Pirates.

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Orioles at Cubs projected starters

LHP Cole Irvin vs. RHP Kyle Hendricks

Irvin (1-2, 7.85 ERA) makes his 5th start and 6th appearance. He has a 1.75 WHIP, 3.9 BB/9 and 8.8 K/9 in 18 1/3 innings.

  • Last start: Win, 5 1/3 IP, 1 ER, 6 H, 0 BB, 5 K in a 6-1 win vs. Kansas City Royals Saturday
  • Only career start vs. Cubs: Loss, 4 2/3 IP, 7 ER, 7 H, 3 BB, 6 K in an 8-4 road loss May 5, 2022

Hendricks (1-2, 3.09 ERA) makes his 5th start. He has a 1.07 WHIP, 2.3 BB/9 and 5.8 K/9 in 23 1/3 innings.

  • Last start: Win, 8 IP, 0 ER, 1 H, 1 BB, 3 K in a 4-0 win at San Francisco Giants Saturday
  • Only career start vs. Orioles: No-decision, 2 IP, 2 ER, 5 H, 0 BB, 2 K in a 7-2 win at home Aug. 8, 2014

Orioles at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:05 a.m. ET.

  • Moneyline (ML): Orioles -110 (bet $110 to win $100) | Cubs -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Orioles -1.5 (+150) | Cubs +1.5 (-185)
  • Over/Under (O/U): 8.5 (O: -105 | U: -115)

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Orioles at Cubs picks and predictions

Prediction

Orioles 5, Cubs 4

Moneyline

The Orioles have won 6 of their last 7 games and are 4-1 in their last 5 interleague games vs. teams with a losing record. The Cubs have lost last their last 4 interleague games and are just 1-4 in their last 5 after allowing 2 or fewer runs.

BET ORIOLES (-110).

Run line/Against the spread

With Irvin on the mound for Baltimore, the Cubs should be able to score enough runs to keep it close. Chicago +1.5 (-185) should hit, but there’s no need to pay the higher price on the run line when Baltimore ML is the better play. Bet Orioles ML and/or the total instead.

PASS.

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Over/Under

The Over has hit in the Cubs’ last 4 games and 7 of their last 10 at home. The Orioles are averaging 6.75 runs over their last 4 games and that coupled with Irvin’s inconsistency as a starter should help the Over cash once again Friday.

BET OVER 8.5 (-105).

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Baltimore Orioles at Chicago Cubs odds, picks and predictions

Analyzing Wednesday’s Baltimore Orioles at Chicago Cubs odds and lines, with MLB expert picks and predictions.

The Baltimore Orioles (44-44) and Chicago Cubs (34-53) meet Wednesday to cap off a 2-game interleague set at Wrigley Field. First pitch is scheduled for 8:05 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Orioles vs. Cubs odds with MLB picks and predictions.

Season series: Baltimore leads 2-0. The teams will make up a rained-out game at Balitmore from June 8 on Aug. 18.

The Orioles arrived in Chicago with an 8-game win streak in tow. Baltimore won Tuesday’s game 4-2 and is now 20-11 over its last 31 games. The 9-game win streak is Baltimore’s longest since 1999.

The Cubs are an inverse 11-20 over their last 31. Albeit in close games — all by 1 or 2 runs — Chicago has lost 5 in a row.

Orioles at Cubs projected starters

RHP Spenser Watkins vs. LHP Justin Steele

Watkins (2-1, 4.15 ERA) has logged a 1.38 WHIP, 3.4 BB/9 and 4.9 K/9 through 47 2/3 IP in 12 starts.

  • Owns a 1.02 ERA, 0.85 WHIP since returning from a forearm injury June 25.
  • Is a fly-ball pitcher who has benefited from a low 7.7% rate of such hits leaving the yard.

Steele (3-5, 4.13 ERA) is tabbed for his 17th start. He has a 1.43 WHIP, 4.2 BB/9 and 9.0 K/9 in 76 1/3 IP.

  • Has yielded 2 runs or less in 5 of his last 6 starts. Owns a 2.72 ERA over that stretch (1.88 at Wrigley).
  • Being activated from the Paternity List for this start. Last pitched July 4 at Milwaukee (6 IP, 2 H, 1 R, 4 BB and 9 K).

Orioles at Cubs odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 12:27 p.m. ET.

  • Money line: Orioles +120 (bet $100 to win $120) | Cubs -145 (bet $145 to win $100)
  • Run line (RL): Orioles +1.5 (-180) | Cubs -1.5 (+145)
  • Over/Under (O/U): 8.5 (O: -102 | U: -122)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Orioles at Cubs picks and predictions

Prediction

Cubs 4, Orioles 3

Money line

Peg Baltimore as being a bit overrated right now and a Cubs relief corps being due for better days.

Watkins has been buoyed by a low .277 batting average on balls in play to go alongside his low rate of home runs. he’s a fly-ball pitcher and that plays into a Chicago strength.

Steele has had to negotiate the traffic of a .313 BABIP and a low 68% left-on-base rate. The Cubs own a .762 OPS in their last 13 games and an .889 mark in their last 6 at home.

TAKE CHICAGO (-145).

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Run line/Against the spread

With leans on the home side and the Under, PASS on getting Chicago by on the run line.

Over/Under

The Cubs bullpen zags against its surface numbers (4.45 ERA heading into the series) and puts a green check in the Under column.

Baltimore’s recent run production isn’t fully supported by a strong OPS. On a cooled-off evening with an inward breeze in the forecast, BACK THE UNDER 8.5 (-122).

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Baltimore Orioles at Chicago Cubs odds, picks and predictions

Analyzing Tuesday’s Baltimore Orioles at Chicago Cubs odds and lines, with MLB expert picks and predictions.

The Baltimore Orioles (43-44) and Chicago Cubs (34-52) meet Tuesday on Chicago’s North Side for the opening of a 2-game interleague set at Wrigley Field. First pitch is scheduled for 8:05 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Orioles vs. Cubs odds with MLB picks and predictions.

Season series: Baltimore leads 1-0.

The Orioles arrive in Chicago with an 8-game win streak in tow. Baltimore is 19-11 over its last 30 games.

The Cubs are an inverse 11-19 over their last 30. Albeit in close games — all by 1 or 2 runs — Chicago has lost 4 in a row.

Orioles at Cubs projected starters

RHP Jordan Lyles vs. RHP Adrian Sampson

Lyles (5-7, 4.50 ERA) is tabbed for his 18th start of the season. He has a 1.40 WHIP, 2.8 BB/9 and 7.4 K/9 through 98 IP.

  • Has fared much better at home than on the road. Owns a 2.72 ERA at Camden Yards and a 5.89 mark abroad.
  • Typically gets fairly deep into games. Has given the O’s 6 IP or more in 4 straight starts.

Sampson (0-0, 2.91 ERA) owns a 1.02 WHIP, 1.2 BB/9 and 7.9 K/9 through 21 2/3 IP across 3 starts and 2 relief appearances.

  • Coming off yielding 1 run in 5 2/3 IP at the Milwaukee Brewers Wednesday.
  • Has allowed 7 ER in 16 IP as a starter this season.
  • Has logged a 4.93 career ERA with starts accounting for half of his 56 games.

Orioles at Cubs odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 8:58 a.m. ET.

  • Money line: Orioles +100 (bet $100 to win $100) | Cubs -120 (bet $120 to win $100)
  • Run line (RL): Orioles +1.5 (-200) | Cubs -1.5 (+160)
  • Over/Under (O/U): 8.5 (O: -130 | U: +105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Orioles at Cubs picks and predictions

Prediction

Cubs 4, Orioles 3

Money line

Leaning into streaks of 3-plus games either way is sometimes best done in small doses, so consider a partial-unit play on Chicago.

Its a play angling into Baltimore being a bit overrated right now and a Cubs relief corps being due for better days.

TAKE CHICAGO (-120) but pass if this tag gets any heavier.

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Run line/Against the spread

Avoid the hefty juice toll: PASS.

Over/Under

Both clubs carry in some mixed signals when it comes to runs scored and allowed. The Cubs bullpen zags against its surface numbers (4.45 ERA) and puts a green check in the Under column.

Baltimore’s recent run production isn’t fully supported by a strong OPS. The Orioles are coming off an undefeated home stand that saw them bat .344 (with a .489 batting average on balls in play) with runners in scoring position.

BACK THE UNDER 8.5 (+105).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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