March Madness: Thursday’s best NCAA Tournament Sweet 16 underdog upset pick and prediction

Assessing Thursday’s NCAA Tournament Sweet 16 betting odds and lines, tabbing the best underdog upset pick and prediction.

The first crazy weekend of March Madness is sadly behind us. Now we’ll get a weekend with 12 high-stakes games starting on Thursday with No. 1 Gonzaga taking on No. 4 Arkansas. The Elite Eight will kick off on Saturday and go into Sunday.

After looking at NCAA Tournament odds and lines, here is Thursday’s best Sweet 16 upset pick among our expert college basketball picks, predictions and bets.

Fans will be treated to two of the three remaining No. 1 seeds taking the court. In addition to the Zags and Arizona, No. 2 Villanova and No. 3 Texas Tech will enter as favorites for Thursday’s games.

Two games (Texas Tech-Duke and Arizona-Houston) are a mere 1.5-point spread while Gonzaga at 9.5 is the largest spread. That said, let’s break down an underdog to back on Thursday.

See alsoFerris Mowers Coaches Poll powered by USA TODAY Sports

Thursday’s best Sweet 16 upset pick

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 7:27 p.m. ET.

Also see: Bet Slippin’ Podcast: March Madness Sweet 16 betting primer

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No. 5 Houston Cougars +1.5 (-107) vs. No. 1 Arizona Wildcats – 9:59 p.m. ET

The Houston Cougars beat the No. 12 UAB Blazers to kick off their run in the tournament. They then faced No. 4 Illinois, one of the best teams in the Big Ten with C Kofi Cockburn, who was second in the conference in points per game at 21.1.

The Cougars were undersized compared to Cockburn, but coach Kelvin Sampson’s game plan execution was perfect, holding the 7-foot center to 19 points and limiting the Fighting Illini’s other scoring options.

While their figures could be inflated due to a weak schedule in the AAC, Houston joins Gonzaga as the only team in the nation with both a top 10 offensive and defensive efficiency rating per Kenpom, which has the Cougars as the second-best team in the country.

Furthermore, the Cougars have the best offensive rebounding rate in the nation, per teamrankings. Considering that Arizona gave up 20 offensive boards to TCU, Houston’s dominance on the glass could be a major advantage.

Arizona is a solid side and has arguably the best scorer in the nation in G Bennedict Mathurin, who willed the Wildcats to victory with a last-possession three to force OT.

I wouldn’t bet on him doing that again. I’ll take the Cougars to continue their impressive tournament run.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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Sweet 16 first look: Houston vs. Arizona odds and lines

Looking at Thursday’s Houston vs. Arizona NCAA Tournament Sweet 16 odds, lines and trends. Here’s what you need to know.

The No. 5 seed Houston Cougars (31-5) and No. 1 seed Arizona Wildcats (33-3) will scratch and claw in a South Region Sweet 16 matchup Thursday. Tip-off from AT&T Center in San Antonio is scheduled for 9:59 p.m. ET. Below, we look at the Houston vs. Arizona odds and lines; check back for our college basketball picks, predictions and bets.

Houston made it through the opening week of the tourney with victories over UAB (82-68 Friday) and Illinois (68-53 Sunday). The No. 15 team in the nation plays a slow-down style. The Cougars are 11-1 over their last 12 games and have held foes fewer than 60 points in six of those wins.

Arizona advanced with wins over Wright State (87-70 Friday) and TCU (85-80 Sunday). The Wildcats needed overtime to get by TCU on Sunday. The nation’s No. 2-ranked team plays at an ultra-fast pace, and they use those extra possessions to their advantage. UA owns the NCAA-I’s ninth most effective field-goal mark (55.9%) on offense and the fourth-best mark on defense (44.1%).

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Houston vs. Arizona odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 10:10 a.m. ET.

  • Money line: Houston +110 (bet $100 to win $110) | Arizona -135 (bet $135 to win $100)
  • Against the spread (ATS): Houston +1.5 (-103) | Arizona -1.5 (-117)
  • Over/Under (O/U): 145.5 (O: -108 | U: -112)

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2021-22 betting stats (including postseason):

  • ML: Houston  31-5 | Arizona 33-3
  • ATS: Houston  24-12 | Arizona 20-15-1
  • O/U: Houston  15-19-2 | Arizona 21-15

Houston vs. Arizona head-to-head

Houston and Arizona have meet six times since 1994. The Wildcats won five of those meetings, including the last three which were in 2006, 2008, and 2009.

The Cougars are 9-4 in tournament play since 2000. They’ve made the region semifinals in each of the last two tournaments.

Arizona is looking to make its first region semifinal since 2017. UA is 32-17 in NCAA games this century.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / USC / Wisconsin / College Football News

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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First look: Arizona at Arizona State odds and lines

Previewing the Arizona Wildcats at Arizona State Sun Devils Week 13 matchup, with college football odds, trends and head-to-head records.

The Arizona Wildcats (1-10, 1-7 Pac-12) visit the rival Arizona State Sun Devils (7-4, 5-3) Saturday at Sun Devil Stadium in Tempe. Kickoff is scheduled for 4 p.m. ET. Below, we look at the Arizona vs. Arizona State odds and lines; check back for our college football picks and predictions.

The Wildcats followed up their 10-3 win over California Nov. 6 with a 38-29 cover against Utah as 24-point underdogs Nov. 13. However, on a short week, the Wildcats were manhandled at Washington State 44-18 last Friday. The Over is 3-1 ATS in their past four outings.

The Sun Devils are coming off a disappointing 24-10 loss at Oregon State. They’re 2-3 SU/1-4 ATS during their late-season swoon over the past five contests. The Under is 3-1 in the previous four tilts.

See alsoAFCA Coaches Poll powered by USA TODAY Sports.

Arizona at Arizona State odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Odds for a full list. Lines last updated Tuesday at 8:15 a.m. ET.

  • Money line: Arizona +700 (bet $100 to win $700) | Arizona State -1200 (bet $1,200 to win $100)
  • Against the spread (ATS): Arizona +20.5, -115 (bet $115 to win $100) | Arizona State -20.5, -105 (bet $105 to win $100)
  • Over/Under (O/U): 53.5, O: -108 (bet $108 to win $100) | U: -112 (bet $112 to win $100)

Also see: Betting 101

2021 betting stats:

  • ML: Arizona 1-10 | Arizona State 7-4
  • ATS: Arizona 6-5 | Arizona State 4-7
  • O/U: Arizona 5-6 | Arizona State 4-7

Arizona at Arizona State head-to-head

Arizona leads the all-time series 49-44-1, but Arizona State has won four straight in the series, including a 70-7 beatdown in Tempe last December.

The Sun Devils have won seven of the past nine straight up, too, while the home team is 6-2 ATS in the past eight meetings and the Over is 7-2 in the past nine in this series.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow Kevin J. Erickson on Twitter. SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Colorado / Florida / Georgia / LSU / Michigan / Michigan State / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / USC / Wisconsin / College Football News

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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