Arizona Cardinals at Minnesota Vikings odds, picks and predictions

Analyzing Sunday’s Arizona Cardinals at Minnesota Vikings odds and lines, with expert NFL picks, predictions and best bets.

The Arizona Cardinals (3-4) take their show on the road Sunday to face the Minnesota Vikings (5-1) in Week 8. Kickoff from U.S. Bank Stadium is set for 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Cardinals vs. Vikings odds, and make our expert NFL picks and predictions.

The Cardinals have yet to string together back-to-back wins and have struggled against teams with winning records, losing to the Kansas City Chiefs (44-21), Los Angeles Rams (20-12), Philadelphia Eagles (20-17) and Seattle Seahawks (19-9). Arizona has been its own worst enemy early in games, being outscored 48-6 in the 1st quarter and consistently trying to recover from early deficits.

The Vikings remain in control of the NFC North after their bye week, with wins over all 3 of their division opponents. Minnesota has been far from dominant but has found ways to win in the 4th quarter, where it has almost outscored opponents by a 2-to-1 mark (51-27).

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Cardinals at Vikings odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 9:36 a.m. ET.

  • Moneyline (ML): Cardinals +160 (bet $100 to win $160) | Vikings -190 (bet $190 to win $100)
  • Against the spread (ATS): Cardinals +3.5 (-108) | Vikings -3.5 (-112)
  • Over/Under (O/U): 49.5 (O: -108 | U: -112)

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Cardinals at Vikings key injuries

Cardinals

  • RB James Conner (ribs) out
  • OL Max Garcia (shoulder) out
  • LB Dennis Gardeck (ankle) out
  • C Rodney Hudson (knee) out
  • OL D.J. Humphries (back) questionable
  • CB Byron Murphy (back) questionable
  • PK Matt Prater (hip) questionable
  • RB Darrel Williams (knee) questionable

Vikings

  • DL Jonathan Bullard (illness) questionable

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Cardinals at Vikings picks and predictions

Prediction

Vikings 27, Cardinals 24

Moneyline

PASS.

The risk if you believe Minnesota (-190) is going to win is almost twice the return. You could consider a small wager on the Cardinals (+150) because I see this game coming down to the wire and the team who has the ball last will likely win, but the value isn’t terrific.

Against the spread

BET THE CARDINALS +3.5 (-108).

The Vikings have a very similar style to last season, with the exception of winning close games instead of losing them. Minnesota led the NFL with 14 1-score games last year, going 6-8. It’s flipped the script this season and is 4-0 in 1-score games.

However, the Vikings have consistently struggled against teams that have elite receivers and quarterbacks who can make big plays with their legs. The Cardinals have both. WR DeAndre Hopkins made his 2022 debut last week and caught 10 passes for 103 yards. He could approach those numbers again against a Vikings defense that plays too much off-man coverage.

Arizona QB Kyler Murray doesn’t run as much as he could, but the Vikings don’t have a speedy defense and he could easily break off a couple of big runs that continue drives and put the Cardinals in a scoring position.

With the RB injuries putting depth into question, the Cardinals may lean more on Murray’s running ability — and there will be chances for big plays.

Over/Under

TAKE THE OVER 49.5 (-108).

The Vikings have scored 28, 28, 29 and 24 points in their last 4 games, which gets you a long way to this the Over. I’m not convinced either defense will be capable of shutting down the other team’s offense.

The Cardinals are averaging just 22.3 points per game – the lowest average since coach Kliff Kingsbury arrived. With Hopkins back, the Cardinals have an elite weapon capable of making big plays and a supporting cast that can do likewise.

It may not hit the Over until well into the 4th quarter, but this game looks to have more touchdowns than field goals, which gets you to the Over quicker than a smashmouth run-first style of play that neither team employs very often.

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