Arizona Cardinals home favorites over San Francisco 49ers in Week 16

The San Francisco 49ers are underdogs in their Week 16 home matchup with the rival Arizona Cardinals.

The Arizona Cardinals (8-6) play their home finale in Week 16 against the San Francisco 49ers (5-9). The two teams will play in one of three Saturday games, kicking off at 4:30 p.m. at State Farm Stadium in Glendale, AZ. Below, we take a look at the early betting odds and lines at BetMGM Sportsbook.

The Cardinals are coming off their second straight win. QB Kyler Murray passed for a career-high 406 yards and had three touchdown passes and a rushing touchdown in a 33-26 victory over the Philadelphia Eagles.

The 49ers lost their third straight game on Sunday, and sixth in their last seven games, falling 41-33 to the Dallas Cowboys. 49ers QB Nick Mullens had two interceptions and lost a fumble, and the team turned the ball over four times in the loss.

49ers at Cardinals betting odds, spread and line

Odds via BetMGM; last updated Monday at 7:55 p.m. ET. 

  • Money line: 49ers +160 (bet $100 to win $160) / Cardinals -190 (bet $190 to win $100) | Bet now
  • Against the spread: 49ers +4, -110 (bet $110 to win $100) / Cardinals -4, -110 (bet $110 to win $100) | Bet now
  • Total: 48.5, Over -110 (bet $110 to win $100) / Under -110 (bet $110 to win $100) | Bet now

New to NFL betting?

The 49ers, at +160 odds, have an implied 38.46% chance of winning, or 8/5 fractional odds. If San Francisco wins outright or loses by fewer than 4 points, a 49ers +4 (-110) bet wins.

Place your legal, online NFL bets in CO, IN, NJ, PA, TN and WV at BetMGM. Risk-free first bet! Terms and conditions apply. Bet now!

At -190 odds, the Cardinals have an implied 65.52% chance of beating the 49ers or 10/19 fractional odds. Arizona must win by 5 or more points for a Cardinals -4 (-110) ATS ticket to cash. A 4-point Arizona win would result in a push.

Also see:

Get some action on this NFL game or others by signing up and betting at BetMGM. If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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Arizona Cardinals are home favorites over Philadelphia Eagles in Week 15

The Philadelphia Eagles are road underdogs in their Week 15 matchup against the Arizona Cardinals.

The Arizona Cardinals (7-6) will face the Philadelphia Eagles (4-8-1) in Week 15 and both teams battle for the postseason. The two teams kick off Sunday afternoon at 4:05 p.m. ET at State Farm Stadium in Glendale, AZ. Below, we take a look at the early betting odds and lines at BetMGM Sportsbook.

The Cardinals are coming off a 26-7 road win over the New York Giants. It ended Arizona’s three-game losing streak and New York’s four-game winning streak. The Cardinals had eight sacks, five by linebacker Haason Reddick, who set a single-game franchise record. QB Kyler Murray had a touchdown pass, RB Kenyan Drake rushed for a score and K Mike Nugent made all four field goals he attempted. Arizona moved back into the seventh seed with the win.

The Eagles gave rookie QB Jalen Hurts his first NFL start on Sunday at home against the New Orleans Saints. They snapped their four-game losing streak as Hurts had 167 passing yards with a touchdown pass and rushed for 106 yards.

Eagles at Cardinals betting odds, spread and line

Odds via BetMGM; last updated Monday at 1:20 p.m. ET. 

  • Money line: Eagles +200 (bet $100 to win $200) / Cardinals -250 (bet $250 to win $100) | Bet now
  • Against the spread: Eagles +5.5, -110 (bet $110 to win $100) / Cardinals -5.5, -110 (bet $110 to win $100) | Bet now
  • Total: 47.5, Over -115 (bet $115 to win $100) / Under -105 (bet $105 to win $100) | Bet now

New to NFL betting?

The Eagles, at +200 odds, have an implied 33.33% chance of winning, or 2/1 fractional odds. If Philadelphia wins outright or loses by five or fewer points, the Eagles +5.5 (-110) bet wins.

Place your legal, online NFL bets in CO, IN, NJ, TN and WV at BetMGM. Risk-free first bet! Terms and conditions apply. Bet now!

At -250 odds, the Cardinals have an implied 71.43% chance of beating the Eagles or 2/5 fractional odds. Arizona must win by at least six points for a Cardinals -5.5 (-110) ATS ticket to cash.

Also see:

Get some action on this NFL game or others by signing up and betting at BetMGM. If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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