Seattle Seahawks home favorites against San Francisco 49ers in Week 8

The San Francisco 49ers open as road underdogs in their Week 8 matchup against the NFC West rival Seattle Seahawks.

The San Francisco 49ers (4-3) head to CenturyLink Field in Week 8 to face the NFC West rival Seattle Seahawks (5-1) Sunday. Below, we look at the early betting odds and lines at BetMGM Sportsbook.

Seattle lost their first game of the year on Sunday Night Football in Week 7 to NFC West rival Arizona Cardinals. The 37-34 overtime Seahawks defeat was the worst game of the season for QB Russell Wilson, who did throw three touchdowns but also three interceptions, including a pick in the red zone and an interception in overtime that led to Arizona’s game-winning field goal.

The 49ers went into Foxborough, Mass., and pummeled the New England Patriots 33-6 in Week 7. The 49ers gained 467 total yards to New England’s 241 (7.4 yards per play compared to 4.9 YPP) and picked off Pats QB Cam Newton three times. San Francisco, again, sustained crucial injuries as RB Jeff Wilson Jr. and WR Deebo Samuel were injured Sunday. Before Wilson exited the game in the third quarter with a high-ankle sprain, he carried the ball 17 times with 112 rushing yards and three touchdowns.

49ers at Seahawks betting odds, spread and line

Odds via BetMGM; last updated Monday at 2:30 p.m. ET.

  • Money line: 49ers +145 (bet $100 to win $145) / Seahawks -176 (bet $176 to win $100) | Bet now
  • Against the spread: 49ers +3.5, -115 (bet $115 to win $100) / Seahawks -3.5, -106 (bet $106 to win $100) | Bet now
  • Total: 53.5, Over -115 (bet $115 to win $100) / Under -106 (bet $106 to win $100) | Bet now

New to NFL betting?

Seattle is a -176 favorite with a win probability of 63.77% or fractional odds of 25/44 (1.57 decimal odds) in Week 8. The Seahawks need to win by 4 or more points for a Seahawks -3.5 (-106) bet to win.

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The 49ers are road underdogs with an implied win probability of 40.82%. Those odds are expressed fractionally as 29/20 or 2.45 decimal odds. If San Francisco wins outright or loses by fewer than 4 points, a 49ers +3.5 (-115) ticket cashes.

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