The Stanford Cardinal (1-1) and Vanderbilt Commodores (1-1) meet for a non-conference matchup Saturday at Vanderbilt Stadium in Nashville, Tenn. Kickoff is set for 8 p.m. ET. Below, we look at the Stanford at Vanderbilt odds and lines, and make our expert college football picks, predictions and bets.
Stanford is coming off an impressive 42-28 win against rival USC last week. It might have found its man in doing so with QB Tanner McKee, who went 16-for-23 for 234 yards and 2 TD after splitting duties with Jack West in Week 1. The Cardinal rush defense has been porous (192.5 yards per game), but they’ve been pretty stout against the pass through two games.
Vanderbilt recovered from an embarrassing Week 1 loss to East Tennessee State by knocking off Colorado State 24-21 on the road in Week 2. It was the Commodores’ first win since the 2019 season. The run game has been a problem for Vanderbilt both offensively (94.5 yards per game; 114th nationally) and defensively (193.0 yards allowed per game; 103rd nationally).
Stanford at Vanderbilt odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 1:05 p.m. ET.
- Money line: Stanford -520 (bet $520 to win $100) | Vanderbilt +370 (bet $100 to win $370)
- Against the spread (ATS): Stanford -12.5 (-108) | Vanderbilt -12.5 (-112)
- Over/Under (O/U): 49.5 (O: -105 | U: -115)
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Stanford at Vanderbilt odds, lines, picks and predictions
Prediction
Stanford 34, Vanderbilt 20
Money line
It’s hard to see Vanderbilt winning this one straight up given how it’s looked in its first two games. PASS on the money line given the minuscule payout on Stanford.
Against the spread
Despite the win over Colorado State last week, Vanderbilt was outgained by over 100 yards and this will be its first game against a Power 5 opponent.
Stanford showed significant improvement from Week 1 to Week 2 and looked crisp on offense with McKee under center.
There’s some hangover risk on the road after the Cardinal’s big win over USC last week, but STANFORD -12.5 (-108) is the play.
Over/Under
Take the OVER 49.5 (-105) on what looks like a pretty low line. All but two of Stanford’s last eight games have gone over this number dating back to last season.
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