St. Louis Cardinals at Tampa Bay Rays odds, picks and predictions

Analyzing Wednesday’s St. Louis Cardinals at Tampa Bay Rays odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (49-65) and the Tampa Bay Rays (69-46) play the middle contest of a 3-game interleague series Wednesday at Tropicana Field. First pitch is scheduled for 6:40 p.m. ET (ESPN+). Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Rays odds and make our expert MLB picks and predictions for the best bets.

Season series: Rays lead 1-0 after Tuesday’s 4-2 series-opening win

The Cardinals have dropped 4 of the past 5 games overall and are 2-5 across the previous 7 outings on the road. St. Louis has dropped 3 of the past 4 interleague outings, too. The Under has hit in 3 straight for the Cards and has cashed 8 of their last 10 games.

The Rays have picked up 2 straight wins while going 6-2 in the previous 8 games overall. The Under is on a 3-1 run for Tampa Bay as the total has gone low in 5 of the past 7 outings overall. The Rays have picked up wins in 3 of the past 4 interleague games after a 7-game losing skid vs. the National League.

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Cardinals at Rays projected starters

RHP Dakota Hudson vs. LHP Jalen Beeks

Hudson (2-0, 4.10 ERA) makes his 3rd start and 9th appearance. He has a 1.37 WHIP, 3.4 BB/9 and 6.8 K/9 in 26 1/3 innings.

  • Last start: Win, 7 IP, 3 ER, 2 H, 3 BB, 7 K in 7-3 home win vs. Minnesota Twins last Wednesday
  • 2023 road splits: 0-0, 3.00 ERA (6 IP, 2 ER – 1 HR), .227 opponent batting average (OBA) in 3 relief appearances

Beeks (2-3, 6.27 ERA) makes his 8th start and 28th appearance. He has a 1.47 WHIP, 4.6 BB/9 and 9.6 K/9 in 37 1/3 innings.

  • Last start: No-decision, 1 2/3 IP, 0 ER, 2 H, 1 BB, 3 K in 2-1 road loss vs. Oakland Athletics June 13
  • 2023 home splits: 2-0, 5.12 ERA (19 1/3 IP, 11 ER – 3 HR), .213 OBA in 3 starts and 12 relief appearances

Cardinals at Rays odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:33 a.m. ET.

  • Moneyline (ML): Cardinals +130 (bet $100 to win $130) | Rays -155 (bet $155 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-150) | Rays -1.5 (+125)
  • Over/Under (O/U): 9.5 (O: -110 | U: -110)

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Cardinals at Rays picks and predictions

Prediction

Cardinals 5, Rays 4

Moneyline

The CARDINALS (+130) are worth playing as moderate underdogs in the middle game of this series.

Beeks has been shaky as an opener for the Rays and was banished to Triple-A Durham as a result. He returns for the first time since a relief appearance on July 4, and he makes his first start since June 13. Expect the Cardinals to come alive against him, getting off to an early start in a bullpen game for Tampa.

Run line/Against the spread

The CARDINALS +1.5 (-150) are not priced out of line if you’d like a little insurance and just can’t play St. Louis straight up.

St. Louis is 12-4 in the past 16 games as an underdog on the run line, winning straight up in 8 of those outings.

The Rays cashed on the run line as a favorite in the series opener Tuesday and are 5-1 in the past 6 on the run line as favorites so go lightly on the Cards. However, Beeks should get the Rays started off on the wrong foot.

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Over/Under

UNDER 9.5 (-110) is the lean, but go lightly.

The Under is 3-1 in the past 4 games for the Rays and has cashed in 18 of their past 26 contests overall.

The Under cashed in the series opener and is 5-1 across the Cards’ past 6 interleague outings. Overall, the Under has cashed in 3 straight for St. Louis and 8 of the previous 10 contests.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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