St. Louis Cardinals at Seattle Mariners odds, picks and predictions

Analyzing Friday’s St. Louis Cardinals at Seattle Mariners odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (8-11) and Seattle Mariners (8-11) meet Friday for the opening game of a 3-game series. First pitch from T-Mobile Park is set for 10:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Mariners odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since 2019 season when Cardinals won 2 of 3 games; St. Louis leads all-time series 11-7

St. Louis won 14-5 as -201 home favorites Wednesday vs. the Arizona Diamondbacks after dropping the 1st 2 games of the series. The Cardinals only went 3-4 during their 7-game homestand, but are a hot-hitting team. St. Louis ranks 4th in batting average (.274) and 3rd in hits (181).

Seattle is 3-3 on their current 9-game homestand. They lost 5-3 as -131 home favorites vs. the Milwaukee Brewers Wednesday. After sweeping Colorado at home they were swept by the Brewers.

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Cardinals at Mariners projected starters

LHP Steven Matz vs. RHP George Kirby

Matz (0-2, 6.48 ERA) makes his 4th start. He has a 1.80 WHIP, 4.3 BB/9 and 9.2 K/9 in 16 2/3 IP.

  •  Last start vs. Seattle was Aug. 15, 2021, as a member of the  Toronto Blue Jays; 5 IP, 3 H, 0 ER, 3 BB, 4 K and a win
  • In 9 road appearances (6 starts) last season: 26 IP, 23 H, 13 ER, 7 BB, 30 K

Kirby (1-1, 3.78 ERA) makes his 4th start. He has a 1.26 WHIP, 0.5 BB/9 and 6.5 K/9 in 16 2/3 IP.

  • First time pitching against St. Louis
  • Was 3-3 in 13 home starts last season; 71 1/3 IP, 77 H, 26 ER, 10 BB, 77 K

Cardinals at Mariners odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:38 a.m. ET.

  • Moneyline (ML): Cardinals +110 (bet $100 to win $110) | Mariners -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-185) | Mariners -1.5 (+150)
  • Over/Under (O/U): 8 (O: -110 | U: -110)

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Cardinals at Mariners picks and predictions

Prediction

Mariners 4, Cardinals 2

Moneyline

LEAN MARINERS (-135).

The Mariners are only 5-8 at home this season which is why I am more confident in the O/U bet than this one. The Cardinals are a very solid team  and have the potential to put up 8+ runs any given night. The Mariners are still the safer lean here because the Cardinals inconsistency on pitching and on defense is what is hurting them.

Run line/Against the spread

AVOID. 

The risk at Cardinals +1.5 (-185) is not worth the potential payout here. The Cardinals are a decent road team (3-3), but don’t often play in close games. They are 1-2 in 1-run games this year and while they very well could make this a close game, or even win, this bet is not a safe one.

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Over/Under

BET UNDER 8 (-110).

For St. Louis the Under is 3-0-1 in Matz’s last 4 starts on grass and for Seattle the Under is 4-0 in their last 4 interleague home games vs. a left-handed starter.

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