The St. Louis Cardinals (14-10) visit the San Francisco Giants (14-10) Thursday for the start of a 4-game series at Oracle Park. First pitch is scheduled for 9:45 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Cardinals vs. Giants odds with MLB picks and predictions.
St. Louis won 3 of its last 4 games, including a 2-1 series win in an interleague set against the Kansas City Royals Monday through Wednesday.
San Francisco has lost 5 of its last 6 games including 3 straight – 2 at the Los Angeles Dodgers (Tuesday and Wednesday) and 1 vs. the Washington Nationals (Sunday at Oracle).
The Cardinals beat the Giants 4-2 in last year’s season series despite being outscored 22-20.
Cardinals at Giants projected starters
RHP Miles Mikolas vs. RHP Logan Webb
Mikolas (1-1, 1.52 ERA) lost to the Arizona Diamondbacks 2-0 Saturday, hurling 7 1/3 IP with 2 ER on 4 H, 2 HR, 0 BB and 7 K.
- He has a 2.89 FIP, 0.84 WHIP and 7.6 K/9 in 29 2/3 IP over 5 starts.
Webb (3-1, 3.26 ERA) beat Washington 9-3 Saturday, throwing 6 IP, allowing 3 ER on 11 H and 1 BB with 3 K.
- Has a 2.80 FIP, 1.29 WHIP and 5.9 K/9 in 30 1/3 IP across 5 starts.
- Last season vs. the Cardinals: One start – a no-decision, 7-2 Giants road victory in mid-July – 4 IP, 1 ER, 5 H, 1 HR, 1 BB, 2 K.
Cardinals at Giants odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:57 p.m. ET.
- Money line (ML): Cardinals +110 (bet $100 to win $110) | Giants -135 (bet $135 to win $100)
- Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-200) | Giants -1.5 (+160)
- Over/Under (O/U): 6.5 (O: -135 | O: +110)
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Cardinals at Giants picks and predictions
Prediction
Giants 4, Cardinals 2
Money line
BET GIANTS (-135).
San Francisco is 16-0 in Webb’s home starts since the beginning of 2021. Plus, the Giants lineup hits much better vs. right-handed pitching than St. Louis’.
Giants hitters rank 10th in both wRC+ (109) and hard-hit rate (30.9%) and eighth in wOBA (.316), according to FanGraphs.
The Cardinals rank 22nd in wRC+ (90), 23rd in wOBA (.286) and 29th in hard-hit rate (23.5%).
BET 1 UNIT on the GIANTS (-135).
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Run line/Against the spread
PASS.
The Giants are just 2-8 ATS as home favorites, while the Cardinals are 5-2 ATS as road underdogs.
Over/Under
LEAN to the UNDER 6.5 (+110).
This line is accurately priced and there isn’t much value on either side of the total.
The reason for the Under lean:
- Both starters are “top-of-the-rotation” pitchers
- Webb’s numbers are far better at home than on the road
- Mikolas has pitched at Cy Young-caliber form to start the year
- St. Louis is 2-5 O/U as road underdogs
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