St. Louis Cardinals at New York Yankees odds, picks and predictions

Analyzing Sunday’s St. Louis Cardinals at New York Yankees odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (68-68) and New York Yankees (79-57) close out their weekend series in the Bronx with a Sunday matinee. The first pitch at Yankee Stadium is slated for 1:35 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Yankees odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The Cardinals bounced back with a 6-5 Saturday win after losing Friday’s series opener 6-3. On Saturday, St. Louis went 4-of-6 with runners in scoring position; for the series the Redbirds are 7-for-12.

The Yankees have lost 3 of their last 4 games. They have not been impressive at home. New York is just 13-16 over its last 29 games at Yankee Stadium.

Cardinals at Yankees projected starters

RHP Miles Mikolas vs. LHP Nestor Cortes

Mikolas (8-10, 5.23 ERA) is lined up for his 28th start. He has a 1.26 WHIP, 1.4 BB/9 and 6.1 K/9 in 149 2/3 IP.

  • Last outing: No-decision, 5 2/3 IP, 4 ER, 6 H, 1 BB, 3 K in 7-5 loss vs. San Diego Padres Tuesday
  • Career vs. Yankees: 1-0, 2.45 ERA (7 1/3 IP, 2 ER), 4 H, 2 BB, 3 K in 1 game
  • Making this start on 4 days’ rest and has struggled with that interval in 2024 (5.15 ERA in 9 starts)

Cortes (8-10, 3.89 ERA) is making his 28th start. He has a 1.14 WHIP, 1.8 BB/9 and 8.3 K/9 in 155 IP.

  • Last outing: Win, 6 2/3 IP, 1 ER, 4 H, 2 BB, 5 K in 5-2 win at Washington Nationals Monday
  • Career vs. Cardinals: 0-0, 3.38 ERA (5 1/3 IP, 2 ER), 1 H, 4 BB, 4 K in 1 game
  • Has allowed just 1 run over his last 20 2/23 IP; that surge comes on the heels of posting a 9.26 ERA from July 11-Aug. 8

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Cardinals at Yankees odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:12 a.m. ET.

  • Moneyline: Cardinals +170 (bet $100 to win $170) | Yankees -210 (bet $210 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-115) | Yankees -1.5 (-105)
  • Over/Under (O/U): 9 (O: -105 | U: -115)

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Cardinals at Yankees picks and predictions

Prediction

Yankees 6, Cardinals 5

Moneyline

The analytics make for some lean away from the season ERAs, toward Mikolas and away from Cortes. Given the odds on the table, PASS on the ML. Better value can be found in taking the Cards plus a cushion.

Run line/Against the spread

Cortes has benefited from a .176 batting average on balls in play over his last 3 starts. Mikolas has been undone by a .337 BABIP with runners in scoring position.

St. Louis has played a higher-than-league-average number of 1-run games and is 25-18 in those. With New York’s issues at home and with the Redbirds having a bullpen advantage, there is decent value in projecting a game flow that gets St. Louis within 1 or in the lead when this game plays out.

TAKE ST. LOUIS +1.5 (-115).

Over/Under

The weather forecast for the day game at Yankee Stadium includes an outward-blowing breeze. Cortes is a fly-ball pitcher who does fare well at home, but also figures to be recent-bias overrated without merit.

St. Louis does not hit lefties well (.656 OPS), but that’s alongside some shaky BABIP luck. The Cards’ contribution to this total is likely being overlooked.

New York’s troubles at home have largely been pitching-related, not hitting. Add in a couple or 3 bullpen arms being 2 days’ seen; advantage batters.

BACK THE OVER 9 (-105).

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