Seattle Mariners at Cleveland Guardians odds, picks and predictions

Analyzing Friday’s Seattle Mariners at Cleveland Guardians odds and lines, with expert MLB picks, predictions and best bets.

The Seattle Guardians (2-5) open a 3-game series against the Cleveland Guardians (5-2) Friday afternoon. First pitch for the Guardians’ home opener at Progressive Field is scheduled for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Mariners vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 3-1

The Guardians lost 3-0 at the Mariners Opening Day but rebounded by taking the final 3 games of that opening series, outscoring Seattle 17-9. Cleveland then went to Oakland and took 2 of 3, so it has won 5 of 6 since dropping the season opener.

The Mariners dropped 2 of 3 games to the visiting Los Angeles Angels after the Guardians left town. Seattle fell 4-3 (as a +145 underdog) to L.A. and SP Shohei Ohtani in Wednesday’s series finale. The Under 7.5 cashed by a hook, snapping a 3-0 Over run for the M’s.

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Mariners at Guardians projected starters

RHP Logan Gilbert vs. RHP Aaron Civale

Gilbert (0-1, 1.50 ERA) makes his 2nd start of the season, both against the Guardians. He allowed 1 ER — a solo HR by 1B Josh Naylor — on 4 hits and a walk with 7 K’s across 6 innings in a hard-luck, 2-0 loss Saturday to Cleveland.

  • Last season on the road: 8-1, 3.16 ERA (102 2/3 IP, 36 ER), 1.21 WHIP, 98 K, .233 opponent batting average (OBA) in 18 starts
  • Last season during the day: 5-3, 2.85 ERA (79 IP, 25 ER), 1.05 WHIP, 84 K, .214 OBA in 14 starts

Civale (1-0, 0.00 ERA) makes his 2nd start of the season. He was on the winning end of Saturday’s 2-0 contest vs. Cleveland, twirling 7 scoreless innings of 2-hit, 1-walk ball, while striking out 3.

  • Last season at home: 4-3 3.80 ERA (45 IP, 19 ER), 1.07 WHIP, 49 K in 9 starts
  • Last season during the day: 2-4, 5.50 ERA (37 2/3 IP, 23 ER), 1.33 WHIP, 44 K, .259 OBA in 8 starts

Mariners at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:53 a.m. ET.

  • Moneyline (ML): Mariners -105 (bet $105 to win $100) | Guardians -115 (bet $115  to win $100)
  • Run line (RL)/Against the spread (ATS): Mariners -1.5 (+165) | Guardians +1.5 (-200)
  • Over/Under (O/U): 7 (O: -115 | U: -105)

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Mariners at Guardians picks and predictions

Prediction

Mariners 4, Guardians 2

Moneyline

SEATTLE (-105) is worth a look on the road as the Mariners look to spoil the home opener for the Guardians (-115).

While Civale was amazing in the 1st matchup at T-Mobile Park, Gilbert was pretty good himself. The Mariners just didn’t give him any run support, but Gilbert showed last season he has a penchant for bouncing back after a loss. He lost back-to-back starts just once last season, and the Mariners were 6-1 in his last 7 starts of 2022.

Run line/Against the spread

SEATTLE -1.5 (+165) is worth a small play.

The thing about a home opener is that the home team players can’t be fully focused. They’re dealing with finally getting to their summer homes in Cleveland after a long spring training, and they might be dealing with getting tickets for family and friends. It can be a little overwhelming.

While the Mariners have lost 5 of the past 6, they should be all business.

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Over/Under

UNDER 7 (-105) is the lean.

The Over cashed in 2 of the final 3 meetings in Seattle, but that Under was the matchup between Civale and Gilbert.

While I expect a little more offense Friday afternoon than we saw in the 1st matchup between these pitchers, there will also be a breeze from 6-9 mph blowing directly from center field into the face of the batters, keeping the ball down.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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