San Francisco Giants at Los Angeles Dodgers odds, picks and predictions

Analyzing Wednesday’s San Francisco Giants at Los Angeles Dodgers odds and lines, with MLB expert picks and predictions.

The San Francisco Giants (14-9) meet their long-time rival Los Angeles Dodgers (15-7) Wednesday to conclude their 2-game miniseries. First pitch  at Dodger Stadium is set for 10:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Giants vs. Dodgers odds with MLB picks and predictions.

L.A. won the series opener 3-1 Tuesday with Dodgers SP Julio Urias outdueling Giants SP Carlos Rodon. Urias pitched 6 scoreless innings, allowing 4 hits with no walks and 4 Ks.

The Giants beat the Dodgers 10-9 in last year’s regular-season series, but L.A. had a plus-1 run differential in those meetings.

Giants at Dodgers projected starters

LHP Alex Wood vs. RHP Tony Gonsolin 

Wood (2-1, 4.19 ERA) lost his previous outing Friday vs. the Washington Nationals. He went 5 IP, allowing 5 ER on 8 H, 1 HR and 1 BB with 3 K in the 14-4 loss.

  • 2021 vs. the Dodgers: 0-2 with a 4.76 ERA (17 IP, 9 ER), 20 H, 5 HR, 3 BB and 22 K in 3 starts.

Gonsolin (1-0, 1.59 ERA) picked up a no decision in L.A.’s 5-3 loss at the Arizona Diamondbacks April 26. He threw 4 IP, surrendering 3 R (2 ER) on 3 H and 1 BB with 5 K.

  • 2021 vs. the Giants: 0-1 with an 8.10 ERA (3 1/3 IP, 3 ER), 5 H, 2 HR, 4 BB and 3 K.

Giants at Dodgers odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:44 p.m. ET.

  • Money line (ML): Giants +130 (bet $100 to win $130) | Dodgers -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-165) | Dodgers -1.5 (+133)
  • Over/Under (O/U): 7.5 (O: -112 | U: -107)

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Giants at Dodgers picks and predictions

Prediction

Dodgers 5, Giants 3

Money line

LEAN DODGERS (-160) only because there’s an argument to be made in favor of L.A.’s RL instead since the Dodgers have an edge in the 3 most important phases of the game: Starting pitching, relief pitching and hitting.

The Dodgers are 5-1 overall vs. left-handed starters and their lineup is better than San Franciso’s by WAR, wRC+ and BB/K rate, per FanGraphs.

Also, Gonsolin’s pitching peripherals are elite whereas Wood’s are below-average. According to Statcast, Gonsolin grades in the 88th percentile or better in hard-hit rate, expected slugging percentage (xSLG) and barrel rate while Wood is in the 52nd percentile in hard-hit rate, barrel rate and xSLG.

Finally, L.A.’s bullpen is 1st in xFIP, exit velocity, hard-hit rate and WHIP.

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Run line/Against the spread

LEAN DODGERS -1.5 (+133) only because L.A.’s ML is the safer bet. But, the Dodgers are an MLB-best 9-2 RL as home favorites whereas the Giants +1.5 (-175) are just 2-3 RL as road underdogs.

Over/Under

Slight LEAN to the UNDER 7.5 (-107) only because both starters are bottom-of-the-rotation guys and the Over appears to be the sharper play since it’s pricier.

However the Giants-Dodgers are 3-7 O/U in their last 10 meetings, L.A. has played more to the Over as home favorites (4-7 O/U) and San Francisco is 1-3-1 O/U as road underdogs.

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