San Francisco Giants at Houston Astros odds, picks and predictions

Analyzing Monday’s San Francisco Giants at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

The San Francisco Giants (11-16) begin a 3-game series against the Houston Astros (15-13) on Monday at Minute Maid Park. First pitch is scheduled for 8:10 p.m. ET (FS1). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since the 2021 season (Giants won 2-1)

The Giants lost 6-4 to the San Diego Padres on Sunday as they dropped both games in the Mexico City series. San Francisco is on a 3-game losing streak following a 5-game winning streak.

The Astros beat the Philadelphia Phillies 4-3 on Sunday to end a 2-game losing streak. Houston has won 7 of its last 10 games.

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Giants at Astros projected starters

RHP Ross Stripling vs. RHP Luis Garcia

Stripling (0-1, 6.89 ERA) makes his 3rd start. He has a 1.60 WHIP, 2.9 BB/9 and 8.0 K/9 in 15 2/3 IP.

  • Has given up 6 HR in 5 appearances (2 starts)
  • Has a 1-1 record with a 4.97 ERA, 1.82 WHIP, and 6.4 K/9 in 3 career starts against the Astros

Garcia (2-2, 4.00 ERA) makes his 6th start. He has a 1.26 WHIP, 3.3 BB/9 and 10.3 K/9 in 27 IP.

  • Allowed a combined 0 ER on 5 H with 3 BB and 16 K in his last 2 starts after giving up 12 ER on 19 H in his 1st 3 starts
  • Has 7-plus K’s in his last 3 starts and has won back-to-back starts

Giants at Astros odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:26 a.m. ET.

  • Moneyline (ML): Giants +155 (bet $100 to win $155) | Astros -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-125) | Astros-1.5 (+105)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Giants at Astros picks and predictions

Prediction

Astros 5, Giants 2

Moneyline

PASS.

While the Astros are favored to secure the win at home, taking them straight up at nearly -200 odds isn’t worth the risk. That being said, you can pair Garcia’s strikeouts and Houston’s moneyline for decent odds in this contest.

Run line/Against the spread

ASTROS -1.5 (+105) is the pick in this contest after the Giants travel to Houston after playing in high-altitude Mexico City the previous 2 days. On top of that, Stripling has struggled with a whopping 15.4% barrel percentage and a 117.8 mph max EV (exit velocity).

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Over/Under

UNDER 8.5 (-110) is the ideal bet with Garcia taking the mound for the Astros. Garcia has shut out the Toronto Blue Jays and the Tampa Bay Rays in his last 2 starts.

The Astros are 4-0 to the Under in their last 4 interleague games and 5-0 in their last 5 games overall.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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