San Francisco 49ers at Cincinnati Bengals odds, picks and prediction

Analyzing Sunday’s San Francisco 49ers at Cincinnati Bengals Week 14 odds and lines, with expert NFL picks, predictions and best bets.

The San Francisco 49ers (6-6) will face the Cincinnati Bengals (7-5) Sunday afternoon in Week 14. Kickoff is 4:25 p.m. ET at Paul Brown Stadium. Below, we look at the 49ers vs. Bengals odds and lines, and make our best NFL picks, predictions and bets.

The 49ers, after winning three games in a row and four out of five, fell 30-23 to the Seattle Seahawks last week.

QB Jimmy Garoppolo was intercepted twice and sacked once for a safety, and the defense allowed the Seahawks to rush for 146 yards and two touchdowns. San Francisco maintains the No. 7 seed in the NFC.

The Bengals are currently the No. 6 seed in the AFC. They lost at home last week 41-22 to the Los Angeles Chargers. Bengals QB Joe Burrow was picked off twice and Chargers QB Justin Herbert threw three touchdown passes.

49ers at Bengals odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 2:12 p.m. ET.

  • Money line: 49ers -125 (bet $125 to win $100) | Bengals +102 (bet $100 to win $102)
  • Against the spread (ATS): 49ers -1.5 (-115) | Bengals +1.5 (-105)
  • Over/Under (O/U): 49.5 (O: -108 | U: -112)

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49ers at Bengals key injuries

49ers

  • RB Trenton Cannon (concussion) questionable
  • WR Deebo Samuel (groin) questionable
  • LB Dre Greenlaw (groin) out
  • RB Elijah Mitchell (knee) out
  • DL Maurice Hurst (calf) out

Bengals

  • RB Joe Mixon (illness) questionable
  • WR Tee Higgins (ankle) questionable
  • LB Logan Wilson (shoulder) out
  • CB Chidobe Awuzie (foot) questionable

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49ers at Bengals odds, lines, predictions and picks

Prediction

49ers 33. Bengals 30

Money line

The 49ers are 4-2 on the road this season and have scored 30 or more points in four of their last six games.

The Bengals are inconsistent defensively this season. They have allowed over 30 points three times and 13 or fewer points four times.

The 49ers are the same. They have given up 30 or more five times and 17 or fewer four times.

This is a true toss-up game but the 49ers’ only two losses in their last six games were against division opponents.

Take the 49ERS (-125).

Against the spread

With the spread so small, it doesn’t make sense to look at one team on the money line and another ATS.

The 49ers are 5-7 ATS this season compared to the Bengals’ 6-6 ATS record. San Francisco has covered the spread in four of its last six games, while the Bengals have in four of their last seven.

Take the 49ERS -1.5 (-115).

Over/Under

This should be a shootout. The Bengals have had five of their last six games hit the Over. The 49ers have had five of their last seven do the same.

Both teams are capable of scoring and allowing more than 30 points.

Take OVER 49.5 (-108).

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