San Diego Padres at Houston Astros odds, picks and prediction

Analyzing Sunday’s San Diego Padres at Houston Astros odds and lines, with MLB picks and predictions.

The San Diego Padres (34-19) try for the sweep Sunday against the Houston Astros (27-24) in Minute Maid Park at 2:10 p.m. ET. Let’s analyze BetMGM Sportsbook‘s lines around the Padres vs. Astros odds with MLB picks and predictions.

San Diego rallied from a 5-run deficit Saturday in the eighth and ninth innings before beating Houston in a second straight extra-innings game, 11-8.

Padres SS Fernando Tatis Jr. blasted a 3-run shot in the top of the ninth to tie it at 6-all. Tatis also hit a tying solo home run in the top of the eighth in San Diego’s 10-3 extra-innings win Friday over Houston.

Season series: Padres 2-0.

LHP Blake Snell makes his 11th start for the Padres. Snell is 1-1 with a 4.50 ERA (44 IP, 22 ER), 1.52 WHIP, 5.7 BB/9 and 13.7 K/9 this season.

  • Last outing: Loss, 5-3, in 3 2/3 IP with 5 ER, 5 H, 3 BB and 7 K Monday at the Milwaukee Brewers.
  • Career vs. Astros: 2-2 with a 4.73 ERA (32 1/3 IP, 17 ER), 1.49 WHIP and 8.6 K/9 over six regular-season starts.
    • Snell was 1-1 in his two starts against the Astros in the 2020 American League Championship Series (Games 1 and 6) with 9 IP, 3 ER, 9 H, 6 BB and 6 K.
    • vs. Astros on the current roster (including postseason): 107 at-bats with a .308/.393/.561 slash line, 21/15 K/BB, 7 HR and 12 RBIs.

RHP Zack Greinke is the projected starter for the Astros. Greinke is 4-2 with a 3.97 ERA (65 2/3 IP, 29 ER), 1.16 WHIP, 1.9 BB/9 and 7.3 K/9 through 11 starts.

  • Last outing: Loss, 9-2, in 6 IP with 4 ER, 3 H, 3 BB and 5 K Tuesday vs. Los Angeles Dodgers.
  • Career vs. Padres: 13-3 with a 2.44 ERA (169 1/3 IP, 46 ER), 0.92 WHIP and 8.8 K/9 across 26 starts.
    • vs. Padres on the current roster: 129 at-bats with a .178/.243/.271 slash line, 40/11 K/BB, 3 HR and 11 RBIs.

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Padres at Astros odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 4:52 a.m. ET.

  • Money line: Padres -110 (bet $110 to win $100) | Astros -110 (bet $110 to win $100)
  • Against the spread/ATS: Padres -1.5 (+150) | Astros +1.5 (-185)
  • Over/Under: 8 (O: -120 | U: +100)

Prediction

Astros 6, Padres 4

Money line (ML)

BET the ASTROS (-105) FIRST 5 INNINGS for 1 unit because of their edge in the starting pitching department and it avoids a Houston bullpen that has blown two games already this series and has struggled on the year.

Houston’s lineup is ranked in the top 5 vs. left-handed pitching in several advanced hitting metrics such as wRC+, wOBA, BB/K rate and hard-hit rate.

Furthermore, Snell has a 7.23 FIP, .393 wOBA and 15.6% strikeout rate vs. Astros on the current roster (109 plate appearances) while Greinke has a 3.14 FIP, .230 wOBA and 27.8% strikeout rate vs. current Padres (133 plate appearances).

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Run line/Against the spread (ATS)

Slight “LEAN” to the ASTROS -0.5 (+155) FIRST 3 INNINGS alternate run line because the top of Houston’s order hits well against Snell, who has been behind after three innings in six of his 10 starts this season.

Over/Under (O/U)

PASS since the Over has cashed in the first two games of this series with late- or extra-inning rallies because Houston’s bullpen cannot hold a lead.

Also, the Astros hitters have done alright in the batter’s box against Snell so that, and the price-point rules out the Under 4.5 (-125) First 5 Innings.

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