San Diego Padres at Arizona Diamondbacks odds, picks and predictions

Analyzing Thursday’s San Diego Padres at Arizona Diamondbacks odds and lines, with MLB expert picks and predictions.

The San Diego Padres (78-65) continue their road trip Thursday, kicking off a 4-game series against the Arizona Diamondbacks (67-75) for their final series against them this season. First pitch is 9:40 p.m. ET at Chase Field. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Diamondbacks odds with MLB picks and predictions.

Season series: Padres lead 11-4

The Padres are coming off a 2-game series they split on the road against the Seattle Mariners. They have lost 3 of the last 4 games and 6 of their last 10. They hold a 2-game lead for the final AL wild-card spot.

The Diamondbacks salvaged 1 game in a 3-game series at home against the Los Angeles Dodgers, getting a 5-3 walk-off win in 10 innings Wednesday night. They have just 2 wins in their last 8 games.

Play our free daily Pick’em Challenge and win! Play now!

Padres at Diamondbacks projected starters

LHP Sean Manaea vs. RHP Drey Jameson

Manaea  (7-8, 5.23 ERA) makes his 26th start in 27 appearances. He has a 1.36 WHIP, 3.0 BB/9 and 9.2 K/9 in 139 1/3 IP.

  • Made a 1-inning appearance in relief 5 days ago, but in 2 previous starts has allowed 14 runs in 8 1/3 innings
  • Is 2-0 with 2.88 ERA in 4 starts against Arizona

Jameson is making his major league debut. He was the Diamondbacks’ 1st-round selection in the 2019 draft.

Playing in both Double-A and Triple-A, he was 7-13 with a 6.31 ERA, 1.49 WHIP, 3.1 BB/9, 9.0 K/9 in 132 2/3 IP.

Padres at Diamondbacks odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:39 a.m. ET.

  • Money line (ML): Padres -170 (bet $170 to win $100) | Diamondbacks +135 (bet $100 to win $135)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (-105) | Diamondbacks +1.5 (-120)
  • Over/Under (O/U): 8.5 (O: -135 | U: +110)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Padres at Diamondbacks picks and predictions

Prediction

Padres 5, Diamondbacks 3

Money line

The Diamondbacks simply struggle against the Padres and Los Angeles Dodgers. They have not won more than 1 game in any series against the Padres. Now they go up Manaea, who has pitched well against them in 4 outings. The Padres are 3-1 against Arizona when Manaea is on the mound.

It will be Jameson’s MLB debut, so there is no way to know what to expect from the young pitching prospect.

Take the PADRES (-170).

Run line/Against the spread

The Padres are 39-35 ATS on the road this season. Of their 11 wins over the Diamondbacks, 8 have been by at least 2 runs.

Eleven of the Diamondbacks’ last 12 losses have been by 2 or more runs.

Take the PADRES -1.5 (-105).

Over/Under

Thus far, 10 of the 15 games between the 2 teams have had 8 or fewer runs.

Four of the last 5 games and 8 of the last 13 for the Diamondbacks have had totals of 8 or fewer runs.

Take UNDER 8.5 (+110).

Want action on this game or any other MLB contests? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup[lawrence-newsletter]

[lawrence-auto-related count=3 category=1372]